Results 31 to 40 of about 2,579,458 (259)

The Potential Use of Sialic Acid From Edible Bird’s Nest to Attenuate Mitochondrial Dysfunction by In Vitro Study

Frontiers in Pharmacology, 2021
Edible bird’s nest (EBN) is one of the expensive functional foods in herbal medicine. One of the major glyconutrients in EBN is sialic acid, which has a beneficial effect on neurological and intellectual capability in mammals.
Aswir Abd Rashed, Hafandi Ahmad, Siti Khadijah Abdul Khalid, Devi-Nair Gunasegavan Rathi   +3 more
doaj   +1 more source

Structural characterization of the carbohydrate-binding module of NanA sialidase, a pneumococcal virulence factor [PDF]

, 2015
This research was supported by the University of St Andrews and grants provided by the Medical Research Council.Background: Streptococcus pneumoniae Neuraminidase A (NanA) is a multi-domain protein anchored to the bacterial surface.
Helen Connaris, Yang, Lei, Garry L. Taylor, Taylor, Garry Lindsay, Lei Yang, Potter, Jane Alexandra, Connaris, Helen, Jane A. Potter   +7 more
core   +1 more source

The Sodium Sialic Acid Symporter From Staphylococcus aureus Has Altered Substrate Specificity

Frontiers in Chemistry, 2018
Mammalian cell surfaces are decorated with complex glycoconjugates that terminate with negatively charged sialic acids. Commensal and pathogenic bacteria can use host-derived sialic acids for a competitive advantage, but require a functional sialic acid ...
Rachel A. North, Rachel A. North, Rachel A. North, Weixiao Y. Wahlgren, Weixiao Y. Wahlgren, Daniela M. Remus, Daniela M. Remus, Mariafrancesca Scalise, Sarah A. Kessans, Sarah A. Kessans, Elin Dunevall, Elin Claesson, Tatiana P. Soares da Costa, Matthew A. Perugini, S. Ramaswamy, Jane R. Allison, Jane R. Allison, Jane R. Allison, Cesare Indiveri, Rosmarie Friemann, Rosmarie Friemann, Renwick C. J. Dobson, Renwick C. J. Dobson   +22 more
doaj   +1 more source

Cell surface α2,3-linked sialic acid facilitates Zika virus internalization

Emerging Microbes and Infections, 2019
The emergence of neurotropic Zika virus (ZIKV) raised a public health emergency of global concern. ZIKV can cross the placental barrier and infect foetal brains, resulting in microcephaly, but the pathogenesis of ZIKV is poorly understood.
Chee Wah Tan, Catherine Hong Huan Hor, Swee Sen Kwek, Han Kang Tee, I-Ching Sam, Eyleen L. K. Goh, Eng Eong Ooi, Yoke Fun Chan, Lin-Fa Wang   +8 more
doaj   +1 more source

ANALYSIS OF SIALIC ACIDS IN BOVINE INTESTINAL MUCINS [PDF]

, 1984
Molecular species of sialic acids released by mild acid hydrolysis from mucins of bovine small and large intestine were characterized by two dimensional thin layer chromatography and gas chromatography-mass spectrometry.
Masayo, NISHIURA
core   +1 more source

How bacteria utilize sialic acid during interactions with the host: snip, snatch, dispatch, match and attach

, 2022
N -glycolylneuraminic acid (Neu5Gc), and its precursor N-acetylneuraminic acid (Neu5Ac), commonly referred to as sialic acids, are two of the most common glycans found in mammals.
Atack, John M., Day, Christopher J., Jennings, Michael P, Atack, John M, Jennings, Michael P., Day, Christopher J   +5 more
core   +1 more source

Sialic acid content of low density lipoprotein and its relation to lipid concentrations and metabolism of low density lipoprotein and cholesterol

Journal of Lipid Research, 2000
A low sialic acid content in low density lipoprotein (LDL) has been associated with atherogenicity and coronary artery disease (CAD) in many but not all studies. We investigated associations of the sialic acid-to-apolipoprotein B (apoB) ratio of LDL with
Nina Lindbohm, Helena Gylling, Tatu A. Miettinen   +2 more
doaj   +1 more source

Complement receptor 1 is a sialic acid-independent erythrocyte receptor of Plasmodium falciparum. [PDF]

PLoS Pathogens, 2010
Plasmodium falciparum is a highly lethal malaria parasite of humans. A major portion of its life cycle is dedicated to invading and multiplying inside erythrocytes. The molecular mechanisms of erythrocyte invasion are incompletely understood.
Carmenza Spadafora, Gordon A Awandare, Karen M Kopydlowski, Jozsef Czege, J Kathleen Moch, Robert W Finberg, George C Tsokos, José A Stoute   +7 more
doaj   +1 more source

Unraveling the impact of sialic acids on the immune landscape and immunotherapy efficacy in pancreatic cancer

Journal for ImmunoTherapy of Cancer, 2023
Background Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers. Despite the successful application of immune checkpoint blockade in a range of human cancers, immunotherapy in PDAC remains unsuccessful.
Manfred Wuhrer, Louis Boon, Di Wang, Yvette van Kooyk, Ernesto Rodriguez, Joke M M Den Haan, Nadine van Montfoort, Sandra J van Vliet, Kelly Boelaars, Laura Goossens-Kruijssen, Charlotte M de Winde, Dimitri Lindijer, Babet Springer, Irene van der Haar Àvila, Aram de Haas, Laetitia Wehry, Reina E Mebius   +16 more
doaj   +1 more source

Comparison of serum and bronchoalveolar lavage fluid sialic acid levels between malignant and benign lung diseases

BMC Pulmonary Medicine, 2001
Background It is known that tissue and serum sialic acid levels may be altered by malignant transformation. In this study, sialic acid levels were determined in bronchoalveolar lavage fluid (BAL) and serum in two groups of patients with lung cancer and ...
Aydilek Recep, Budak Yasemin, Isitmangil Gulbu, Isitmangil Turgut, Celenk Mehmet   +4 more
doaj   +1 more source