Sialic acid as a biomarker of oral potentially malignant disorders and oral cancer
Indian Journal of Dental Research, 2017 Background: Carcinogenesis is a multistep process where a healthy cell has initially a precancerous stage and finally an early cancerous stage. The process of carcinogenesis can be divided into three stages of initiation, promotion, and progression.
Sonika Achalli +5 more
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Structural basis for human coronavirus attachment to sialic acid receptors
Nature Structural & Molecular Biology, 2019 Coronaviruses cause respiratory tract infections in humans and outbreaks of deadly pneumonia worldwide. Infections are initiated by the transmembrane spike (S) glycoprotein, which binds to host receptors and fuses the viral and cellular membranes.
M. A. Tortorici +10 more
semanticscholar +1 more source
Synthesis of partially O-acetylated N-acetylneuraminic acid using regioselective silyl exchange technology. [PDF]
, 2014 Postglycosylation acetylation of sialic acid imparts unique roles to sialoglycoconjugates in mammalian immune response making structural and functional understanding of these analogues important.
Gervay-Hague, Jacquelyn, Park, Simon S
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Sialic acid utilization by Cronobacter sakazakii [PDF]
, 2013 Background: The Cronobacter genus is composed of seven species, and can cause infections in all age groups. Of particular concern is C. sakazakii, as this species is strongly associated with severe and often fatal cases of necrotizing enterocolitis and ...
Forsythe, S +3 more
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Journal of Inflammation, 2006 Background Serum sialic acid and C reactive protein are the markers for inflammation. The main objective of this study was to determine the sialic acid level in Caribbean type 2 diabetic patients with and without microvascular complications and its ...
Roberts Lesley, Nayak B Shivananda
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Systematic Chemoenzymatic Synthesis of O-Sulfated Sialyl Lewis x Antigens. [PDF]
, 2015 O-Sulfated sialyl Lewis x antigens play important roles in nature. However, due to their structural complexity, they are not readily accessible by either chemical or enzymatic synthetic processes.
Chen, Xi +8 more
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A single residue substitution in the receptor-binding domain of H5N1 hemagglutinin is critical for packaging into pseudotyped lentiviral particles [PDF]
, 2012 © 2012 Tang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited ...
AM Kilpatrick +49 more
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PLoS Pathogens, 2021 Bacterial binding to platelets is a key step in the development of infective endocarditis (IE). Sialic acid, a common terminal carbohydrate on host glycans, is the major receptor for streptococci on platelets.
Meztlli O Gaytán +13 more
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Intramolecular Lactones of Sialic Acids [PDF]
International Journal of Molecular Sciences, 2020 The so-called “sialo-chemical-biology” has become an attractive research area, as an increasing number of natural products containing a sialic acid moiety have been shown to play important roles in biological, pathological, and immunological processes.
P. Rota +4 more
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Conservation of structure and mechanism in primary and secondary transporters exemplified by SiaP, a sialic acid binding virulence factor from Haemophilus influenzae [PDF]
, 2006 Extracytoplasmic solute receptors (ESRs) are important components of solute uptake systems in bacteria, having been studied extensively as parts of ATP binding cassette transporters.
Kelly, D.J. +7 more
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