Results 41 to 50 of about 6,019,441 (302)
Membrane-enclosed multienzyme (MEME) synthesis of 2,7-anhydro-sialic acid derivatives [PDF]
, 2017 Naturally occurring 2,7-anhydro-alpha-N-acetylneuraminic acid (2,7-anhydro-Neu5Ac) is a transglycosylation product of bacterial intramolecular trans-sialidases (IT-sialidases).
Andrew Bell +41 more
core +2 more sources
The Effect of Sialic Acid on MiR-320a and Let-7e Expression in Human Glial Cell Line
Basic and Clinical Neuroscience, 2022 Introduction: Sialic acid is pivotal in various critical physiological events at molecular and cellular levels and pathological processes. Changes in sialic acid concentration are observed in many pathological processes; for example, some available data ...
Negar Noorbakhsh +2 more
doaj
Cell surface α2,3-linked sialic acid facilitates Zika virus internalization
Emerging Microbes and Infections, 2019 The emergence of neurotropic Zika virus (ZIKV) raised a public health emergency of global concern. ZIKV can cross the placental barrier and infect foetal brains, resulting in microcephaly, but the pathogenesis of ZIKV is poorly understood.
Chee Wah Tan +8 more
doaj +1 more source
Constrained sialic acid donors enable selective synthesis of α-glycosides
Science, 2019 Sweet spot for making oligosaccharides Sugars pose a challenge for chemists: how to string together functional group–rich building blocks that can adopt multiple conformations.
N. Komura +8 more
semanticscholar +1 more source
Journal of Lipid Research, 2000 A low sialic acid content in low density lipoprotein (LDL) has been associated with atherogenicity and coronary artery disease (CAD) in many but not all studies. We investigated associations of the sialic acid-to-apolipoprotein B (apoB) ratio of LDL with
Nina Lindbohm +2 more
doaj +1 more source
Biological function of sialic acid and sialylation in human health and disease
Cell Death DiscoverySialic acids are predominantly found at the terminal ends of glycoproteins and glycolipids and play key roles in cellular communication and function. The process of sialylation, a form of post-translational modification, involves the covalent attachment ...
Wengen Zhu +3 more
semanticscholar +1 more source
Sialic acid derivatization for glycan analysis by mass spectrometry
Proceedings of the Japan Academy. Series B, Physical and biological sciences, 2019 Mass spectrometry (MS) is a well-accepted means for analyzing glycans. Before glycan analysis by MS, several chemical derivatizations are generally carried out.
Takashi Nishikaze
semanticscholar +1 more source
Sialic acids in gastropods [PDF]
FEBS Letters, 2001 The occurrence of N‐acetylneuraminic acid and N‐glycolylneuraminic acid residues in preparations of the slug Arion lusitanicus (Gastropoda) was determined by sodium dodecyl sulphate electrophoresis of the proteins followed by lectin blots stained with the sialic acid specific lectin from Maackia amurensis, by the sensitivity of this binding to ...
Bürgmayr, Sabine +2 more
openaire +2 more sources
Synthesis of N-Glycolylneuraminic Acid (Neu5Gc) and Its Glycosides. [PDF]
, 2019 Sialic acids constitute a family of negatively charged structurally diverse monosaccharides that are commonly presented on the termini of glycans in higher animals and some microorganisms.
Chen, Xi +2 more
core +2 more sources
Frontiers in Molecular Biosciences, 2021 All cells are decorated with a highly dense and complex structure of glycan chains, which are mostly attached to proteins and lipids. In this context, sialic acids are a family of nine-carbon acidic monosaccharides typically found at the terminal ...
Cátia Oliveira Soares +9 more
doaj +1 more source