Results 11 to 20 of about 5,135,061 (391)
Sialic acid glycoengineering using N-acetylmannosamine and sialic acid analogs.
Glycobiology, 2019 Sialic acids cap the glycans of cell surface glycoproteins and glycolipids. They are involved in a multitude of biological processes and aberrant sialic acid expression is associated with several pathologies. Sialic acids modulate the characteristics and
S. Moons +4 more
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The Biosynthesis of Sialic Acids
Journal of Biological Chemistry, 1962 Leonard Warren, Herbert Felsenfeld
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Journal of Biological Chemistry, 1966 Sialic acid 9-phosphate synthetase, an enzyme that condenses phosphoenolpyruvate with N-acyl- d -mannosamine 6-phosphate to yield sialic acid 9-phosphate and inorganic phosphate, was purified approximately 800-fold from extracts of hog submaxillary gland. The enzyme was specific for the indicated substrates, and the available data suggest that a single
W. Kündig, Sudhamoy Ghosh, Saul Roseman
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Exploration of the Sialic Acid World
Advances in Carbohydrate Chemistry and Biochemistry, 2018 Sialic acids are cytoprotectors, mainly localized on the surface of cell membranes with multiple and outstanding cell biological functions. The history of their structural analysis, occurrence, and functions is fascinating and described in this review.
R. Schauer, J. Kamerling
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Sialic Acid Mimetics to Target the Sialic Acid-Siglec Axis.
Trends in Biochemical Sciences, 2016 Sialic acid sugars are vital regulators of the immune system through binding to immunosuppressive sialic acid-binding immunoglobulin-like lectin (Siglec) receptors on immune cells. Aberrant sialic acid-Siglec interactions are associated with an increasing number of pathologies including infection, autoimmunity, and cancer.
C. Büll, T. Heise, G. Adema, T. Boltje
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Sialic Acids as Receptors for Pathogens [PDF]
Biomolecules, 2021 Carbohydrates have long been known to mediate intracellular interactions, whether within one organism or between different organisms. Sialic acids (Sias) are carbohydrates that usually occupy the terminal positions in longer carbohydrate chains, which makes them common recognition targets mediating these interactions.
Patrycja Burzyńska +4 more
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Relationship between plasma sialic acid and fibinogen concentration and incident micro-and macrovascular complications in type 1 diabetes [PDF]
, 2008 AIMS/HYPOTHESIS: Type 1 diabetes is associated with an increased risk of vascular complications. This increased risk could be explained by sialic acid and/or fibrinogen.
CHATURVEDI N +5 more
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Sialic acids in gastropods [PDF]
FEBS Letters, 2001 The occurrence of N‐acetylneuraminic acid and N‐glycolylneuraminic acid residues in preparations of the slug Arion lusitanicus (Gastropoda) was determined by sodium dodecyl sulphate electrophoresis of the proteins followed by lectin blots stained with the sialic acid specific lectin from Maackia amurensis, by the sensitivity of this binding to ...
Sabine Bürgmayr +2 more
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Usefulness of sialic acid for diagnosis of sepsis in critically ill patients: a retrospective study
BMC Anesthesiology, 2020 Background Early diagnosis of sepsis is very important. It is necessary to find effective and adequate biomarkers in order to diagnose sepsis. In this study, we compared the value of sialic acid and procalcitonin for diagnosing sepsis.
Bo Yao +4 more
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Intramolecular Lactones of Sialic Acids [PDF]
International Journal of Molecular Sciences, 2020 The so-called “sialo-chemical-biology” has become an attractive research area, as an increasing number of natural products containing a sialic acid moiety have been shown to play important roles in biological, pathological, and immunological processes.
P. Rota +4 more
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