Results 11 to 20 of about 113,461 (351)
Journal of Biological Chemistry, 1966 Sialic acid 9-phosphate synthetase, an enzyme that condenses phosphoenolpyruvate with N-acyl- d -mannosamine 6-phosphate to yield sialic acid 9-phosphate and inorganic phosphate, was purified approximately 800-fold from extracts of hog submaxillary gland. The enzyme was specific for the indicated substrates, and the available data suggest that a single
George W. Jourdian +2 more
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Journal of Biological Chemistry, 1973 Abstract A soluble sialyltransferase was partially purified from colostrum (goat, bovine, and human). This enzyme catalyzed the transfer of sialic acid from cytidine monophospho-sialic acid to β-d-galactopyranosides. When N-acetyllactosamine was the acceptor, the products formed by the colostrum transferase contained sialic acid linked only to C-6 of ...
Bruce A. Bartholomew +2 more
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The Biosynthesis of Sialic Acids
Journal of Biological Chemistry, 1962 Herbert Felsenfeld, Leonard Warren
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Sialic acids in gastropods [PDF]
FEBS Letters, 2001 The occurrence of N‐acetylneuraminic acid and N‐glycolylneuraminic acid residues in preparations of the slug Arion lusitanicus (Gastropoda) was determined by sodium dodecyl sulphate electrophoresis of the proteins followed by lectin blots stained with the sialic acid specific lectin from Maackia amurensis, by the sensitivity of this binding to ...
Sabine Bürgmayr +2 more
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Sialic Acids as Receptors for Pathogens [PDF]
Biomolecules, 2021 Carbohydrates have long been known to mediate intracellular interactions, whether within one organism or between different organisms. Sialic acids (Sias) are carbohydrates that usually occupy the terminal positions in longer carbohydrate chains, which makes them common recognition targets mediating these interactions.
Patrycja Burzyńska +4 more
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Advances in Nutrition, 2012 Early postnatal development encounters milk as a key environmental variable and yet the sole nutrient source. One evolutionary conserved constituent of milk is sialic acid, which is generally displayed on glycoconjugates and free glycans. During early postnatal development, high sialic acid need was proposed to be unmet by the endogenous sialic acid ...
Norbert Sprenger, Peter I. Duncan
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Intramolecular Lactones of Sialic Acids [PDF]
International Journal of Molecular Sciences, 2020 The so-called “sialo-chemical-biology” has become an attractive research area, as an increasing number of natural products containing a sialic acid moiety have been shown to play important roles in biological, pathological, and immunological processes.
P. Rota +4 more
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Synthesis of Sialic Acids and Sialic Acid Derivatives [PDF]
, 1982 Sialic acids as such, sialic acid derivatives, analogues, glycosides and sialooligosaccharides have been subject of many synthetic investigations. These studies were aimed at a further exploration of the properties of sialic acids, the preparation of substrates and inhibitors for sialidases, sialyltransferases or for sialic acid converting enzymes, and
Vliegenthart, J.F.G., Kamerling, J.P.
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Synthesis of partially O-acetylated N-acetylneuraminic acid using regioselective silyl exchange technology. [PDF]
, 2014 Postglycosylation acetylation of sialic acid imparts unique roles to sialoglycoconjugates in mammalian immune response making structural and functional understanding of these analogues important.
Gervay-Hague, Jacquelyn, Park, Simon S
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Systematic Chemoenzymatic Synthesis of O-Sulfated Sialyl Lewis x Antigens. [PDF]
, 2015 O-Sulfated sialyl Lewis x antigens play important roles in nature. However, due to their structural complexity, they are not readily accessible by either chemical or enzymatic synthetic processes.
Chen, Xi +8 more
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