Results 21 to 30 of about 113,461 (351)

Increased expression of sialic acid in cervical biopsies with squamous intraepithelial lesions

Diagnostic Pathology, 2010
Background Altered sialylation has been observed during oncogenic transformation. Sialylated oligosaccharides of glycoproteins and glycolipids have been implicated in tumor progression and metastases.
Vallejo-Ruiz Verónica, Zenteno Edgar, Santos-López Gerardo, Reyes-Leyva Julio, López-Morales Dolores   +4 more
doaj   +1 more source

Membrane-enclosed multienzyme (MEME) synthesis of 2,7-anhydro-sialic acid derivatives [PDF]

, 2017
Naturally occurring 2,7-anhydro-alpha-N-acetylneuraminic acid (2,7-anhydro-Neu5Ac) is a transglycosylation product of bacterial intramolecular trans-sialidases (IT-sialidases).
Andrew Bell, Angata, Bednarski, Chen, Chokhawala, Chokhawala, Crost, Crost, Dimitrios Latousakis, Etzold, Furuhata, Gerardy-Schahn, Gwenaelle Le Gall, Hai Yu, Ian J. Colquhoun, Juge, Juge, Lee, Lewis, Li, Li, Lifely, Louise E. Tailford, Luo, Luo, Marie Monestier, Martin Rejzek, Nathalie Juge, Ouwerkerk, Robert A. Field, Rohrer, Sandra Tribolo, Savage, Schauer, Schroder, Simone Dedola, Suzuki, Tailford, Tailford, Varki, Xi Chen, Yu   +41 more
core   +2 more sources

Sialic acid and crystal binding [PDF]

Kidney International, 2000
We studied the role of cell surface sialic acid in the adherence of calcium oxalate monohydrate (COM) crystals to Madin-Darby canine kidney (MDCK) cells.Studies were performed with undifferentiated (crystal-binding) cells in subconfluent cultures and maturated (noncrystal-binding) cells in confluent cultures.
Burt G. van der Boom, Carl F. Verkoelen, Dirk J. Kok, Johannes C. Romijn   +3 more
openaire   +4 more sources

Sialic acid as a biomarker of oral potentially malignant disorders and oral cancer

Indian Journal of Dental Research, 2017
Background: Carcinogenesis is a multistep process where a healthy cell has initially a precancerous stage and finally an early cancerous stage. The process of carcinogenesis can be divided into three stages of initiation, promotion, and progression.
Sonika Achalli, Medhini Madi, Subhas G Babu, Shishir Ram Shetty, Suchetha Kumari, Supriya Bhat   +5 more
doaj   +1 more source

A single residue substitution in the receptor-binding domain of H5N1 hemagglutinin is critical for packaging into pseudotyped lentiviral particles [PDF]

, 2012
© 2012 Tang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited ...
AM Kilpatrick, AN Abdel-Ghafar, B Labrosse, Béatrice Nal, C Tsai, Chi-Hong Lam, DA Senne, DA Steinhauer, Dong-Jiang Tang, DP Nayak, G Kayali, GM Air, H Chen, H Imai, HD Klenk, I Nefkens, J Szecsi, J. S. Malik Peiris, JJ Skehel, JM Garcia, JM Garcia, JM Moore, JS Peiris, L Houzet, M Lakadamyali, M Matrosovich, M Naughtin, MR Sandbulte, P Auewarakul, P Benaroch, Philippe Buchy, RG Webster, Roberto Bruzzone, RP de Vries, S Barman, S Yamada, Shui-Ling Chu, SL Deutscher, Stefan Pöhlmann, SY Wang, T Dung Nuyen, T Horimoto, T McKay, T Rowe, V Bosch, VC Chu, Y Suzuki, Yu-Lam Siu, Yuen-Man Lam, Z Ao   +49 more
core   +8 more sources

Sialic Acid Metabolism: A Key Player in Breast Cancer Metastasis Revealed by Metabolomics

Frontiers in Oncology, 2018
Metastatic breast cancer is currently incurable. It has recently emerged that different metabolic pathways support metastatic breast cancer. To further uncover metabolic pathways enabling breast cancer metastasis, we investigated metabolic differences in
Shao Thing Teoh, Martin P. Ogrodzinski, Martin P. Ogrodzinski, Christina Ross, Kent W. Hunter, Sophia Y. Lunt, Sophia Y. Lunt   +6 more
doaj   +1 more source

Diversity in the sialic acids [PDF]

Glycobiology, 1992
Historical background It is now more than 50 years since N-acetyl-neuraminic acid was first discovered and subsequently characterized by several groups (reviewed in Roseman, 1970; Gottschalk, 1972; Rosenberg and Schengrund, 1976; Schauer, 1982; Faillard, 1989).
openaire   +4 more sources

Sialic acid transporter NanT participates in Tannerella forsythia biofilm formation and survival on epithelial cells [PDF]

, 2016
Tannerella forsythia is a periodontal pathogen implicated in periodontitis. This gram-negative pathogen depends on exogenous peptidoglycan amino sugar N-acetylmuramic acid (NAM) for growth.
Frey, A.M., Honma, K., Ruscitto, A., Sharma, A., Stafford, G.P.   +4 more
core   +1 more source

Sialic acids and viruses

, 2021
Let us study viruses and the role of sialic acids in their first step of reproduction, the attachment to cells. We begin our study with the help of the "Earth's virology course", created by Vincent Racaniello, with David Tuller and Gertrud U. Rey. The first virus that we will study is that of influenza A. Actually, "Earth's virology course" is a proper
openaire   +1 more source

Relationship between inflammatory markers, metabolic and anthropometric variables in the Caribbean type 2 diabetic patients with and without microvascular complications

Journal of Inflammation, 2006
Background Serum sialic acid and C reactive protein are the markers for inflammation. The main objective of this study was to determine the sialic acid level in Caribbean type 2 diabetic patients with and without microvascular complications and its ...
Roberts Lesley, Nayak B Shivananda
doaj   +1 more source