Results 31 to 40 of about 5,135,061 (391)

A single residue substitution in the receptor-binding domain of H5N1 hemagglutinin is critical for packaging into pseudotyped lentiviral particles [PDF]

, 2012
© 2012 Tang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited ...
AM Kilpatrick, AN Abdel-Ghafar, B Labrosse, Béatrice Nal, C Tsai, Chi-Hong Lam, DA Senne, DA Steinhauer, Dong-Jiang Tang, DP Nayak, G Kayali, GM Air, H Chen, H Imai, HD Klenk, I Nefkens, J Szecsi, J. S. Malik Peiris, JJ Skehel, JM Garcia, JM Garcia, JM Moore, JS Peiris, L Houzet, M Lakadamyali, M Matrosovich, M Naughtin, MR Sandbulte, P Auewarakul, P Benaroch, Philippe Buchy, RG Webster, Roberto Bruzzone, RP de Vries, S Barman, S Yamada, Shui-Ling Chu, SL Deutscher, Stefan Pöhlmann, SY Wang, T Dung Nuyen, T Horimoto, T McKay, T Rowe, V Bosch, VC Chu, Y Suzuki, Yu-Lam Siu, Yuen-Man Lam, Z Ao   +49 more
core   +8 more sources

Sialic acid as a biomarker of oral potentially malignant disorders and oral cancer

Indian Journal of Dental Research, 2017
Background: Carcinogenesis is a multistep process where a healthy cell has initially a precancerous stage and finally an early cancerous stage. The process of carcinogenesis can be divided into three stages of initiation, promotion, and progression.
Sonika Achalli, Medhini Madi, Subhas G Babu, Shishir Ram Shetty, Suchetha Kumari, Supriya Bhat   +5 more
doaj   +1 more source

The Sialic Acids

Journal of Biological Chemistry, 1973
Abstract A soluble sialyltransferase was partially purified from colostrum (goat, bovine, and human). This enzyme catalyzed the transfer of sialic acid from cytidine monophospho-sialic acid to β-d-galactopyranosides. When N-acetyllactosamine was the acceptor, the products formed by the colostrum transferase contained sialic acid linked only to C-6 of ...
Don M. Carlson, George W. Jourdian, Saul Roseman   +2 more
openalex   +4 more sources

Diversity in the sialic acids [PDF]

Glycobiology, 1992
Historical background It is now more than 50 years since N-acetyl-neuraminic acid was first discovered and subsequently characterized by several groups (reviewed in Roseman, 1970; Gottschalk, 1972; Rosenberg and Schengrund, 1976; Schauer, 1982; Faillard, 1989).
openaire   +4 more sources

Sialic acid transporter NanT participates in Tannerella forsythia biofilm formation and survival on epithelial cells [PDF]

, 2016
Tannerella forsythia is a periodontal pathogen implicated in periodontitis. This gram-negative pathogen depends on exogenous peptidoglycan amino sugar N-acetylmuramic acid (NAM) for growth.
Frey, A.M., Honma, K., Ruscitto, A., Sharma, A., Stafford, G.P.   +4 more
core   +1 more source

Sialic acids and viruses

, 2021
Let us study viruses and the role of sialic acids in their first step of reproduction, the attachment to cells. We begin our study with the help of the "Earth's virology course", created by Vincent Racaniello, with David Tuller and Gertrud U. Rey. The first virus that we will study is that of influenza A. Actually, "Earth's virology course" is a proper
openaire   +5 more sources

Relationship between inflammatory markers, metabolic and anthropometric variables in the Caribbean type 2 diabetic patients with and without microvascular complications

Journal of Inflammation, 2006
Background Serum sialic acid and C reactive protein are the markers for inflammation. The main objective of this study was to determine the sialic acid level in Caribbean type 2 diabetic patients with and without microvascular complications and its ...
Roberts Lesley, Nayak B Shivananda
doaj   +1 more source

A novel sialic acid-binding adhesin present in multiple species contributes to the pathogenesis of Infective endocarditis.

PLoS Pathogens, 2021
Bacterial binding to platelets is a key step in the development of infective endocarditis (IE). Sialic acid, a common terminal carbohydrate on host glycans, is the major receptor for streptococci on platelets.
Meztlli O Gaytán, Anirudh K Singh, Shireen A Woodiga, Surina A Patel, Seon-Sook An, Arturo Vera-Ponce de León, Sean McGrath, Anthony R Miller, Jocelyn M Bush, Mark van der Linden, Vincent Magrini, Richard K Wilson, Todd Kitten, Samantha J King   +13 more
doaj   +1 more source

Structural characterization of the carbohydrate-binding module of NanA sialidase, a pneumococcal virulence factor [PDF]

, 2015
This research was supported by the University of St Andrews and grants provided by the Medical Research Council.Background: Streptococcus pneumoniae Neuraminidase A (NanA) is a multi-domain protein anchored to the bacterial surface.
Connaris, Helen, Potter, Jane Alexandra, Taylor, Garry Lindsay, Yang, Lei   +3 more
core   +1 more source

Elucidation of a unique sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut

Nature Microbiology, 2019
Sialic acid (N-acetylneuraminic acid (Neu5Ac)) is commonly found in the terminal location of colonic mucin glycans where it is a much-coveted nutrient for gut bacteria, including Ruminococcus gnavus. R.
Andrew Bell, Jason Brunt, Jason Brunt, E. Crost, Laura C. Vaux, R. Nepravishta, C. Owen, D. Latousakis, An Xiao, Wanqing Li, Xi Chen, M. Walsh, J. Claesen, J. Angulo, G. Thomas, N. Juge   +15 more
semanticscholar   +1 more source