Results 31 to 40 of about 116,138 (312)

Sialic acid as a biomarker of oral potentially malignant disorders and oral cancer

Indian Journal of Dental Research, 2017
Background: Carcinogenesis is a multistep process where a healthy cell has initially a precancerous stage and finally an early cancerous stage. The process of carcinogenesis can be divided into three stages of initiation, promotion, and progression.
Sonika Achalli, Medhini Madi, Subhas G Babu, Shishir Ram Shetty, Suchetha Kumari, Supriya Bhat   +5 more
doaj   +1 more source

Structural characterization of the carbohydrate-binding module of NanA sialidase, a pneumococcal virulence factor [PDF]

, 2015
This research was supported by the University of St Andrews and grants provided by the Medical Research Council.Background: Streptococcus pneumoniae Neuraminidase A (NanA) is a multi-domain protein anchored to the bacterial surface.
Connaris, Helen, Potter, Jane Alexandra, Taylor, Garry Lindsay, Yang, Lei   +3 more
core   +1 more source

Sialic Acid Metabolism: A Key Player in Breast Cancer Metastasis Revealed by Metabolomics

Frontiers in Oncology, 2018
Metastatic breast cancer is currently incurable. It has recently emerged that different metabolic pathways support metastatic breast cancer. To further uncover metabolic pathways enabling breast cancer metastasis, we investigated metabolic differences in
Shao Thing Teoh, Martin P. Ogrodzinski, Martin P. Ogrodzinski, Christina Ross, Kent W. Hunter, Sophia Y. Lunt, Sophia Y. Lunt   +6 more
doaj   +1 more source

Relationship between inflammatory markers, metabolic and anthropometric variables in the Caribbean type 2 diabetic patients with and without microvascular complications

Journal of Inflammation, 2006
Background Serum sialic acid and C reactive protein are the markers for inflammation. The main objective of this study was to determine the sialic acid level in Caribbean type 2 diabetic patients with and without microvascular complications and its ...
Roberts Lesley, Nayak B Shivananda
doaj   +1 more source

A single residue substitution in the receptor-binding domain of H5N1 hemagglutinin is critical for packaging into pseudotyped lentiviral particles [PDF]

, 2012
© 2012 Tang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited ...
AM Kilpatrick, AN Abdel-Ghafar, B Labrosse, Béatrice Nal, C Tsai, Chi-Hong Lam, DA Senne, DA Steinhauer, Dong-Jiang Tang, DP Nayak, G Kayali, GM Air, H Chen, H Imai, HD Klenk, I Nefkens, J Szecsi, J. S. Malik Peiris, JJ Skehel, JM Garcia, JM Garcia, JM Moore, JS Peiris, L Houzet, M Lakadamyali, M Matrosovich, M Naughtin, MR Sandbulte, P Auewarakul, P Benaroch, Philippe Buchy, RG Webster, Roberto Bruzzone, RP de Vries, S Barman, S Yamada, Shui-Ling Chu, SL Deutscher, Stefan Pöhlmann, SY Wang, T Dung Nuyen, T Horimoto, T McKay, T Rowe, V Bosch, VC Chu, Y Suzuki, Yu-Lam Siu, Yuen-Man Lam, Z Ao   +49 more
core   +9 more sources

The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents [PDF]

, 2005
Strong thrombocytopenia is observed during acute infection with Trypanosoma cruzi, the parasitic protozoan agent of American trypanosomiasis or Chagas' disease.
Campetella, O., Leguizamon, M.S., Mucci, J., Rooijen, N. van, Tribulatti, M.V.   +4 more
core   +2 more sources

Evaluation of serum concentration of sialic acid in foals affected by Rhodococcosis [PDF]

Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2015
This study was conducted for evaluation of sialic acid concentration in serum of 19 foals with Rhodococcosis and compared with 18 normal foals in horse stables in Tabriz area in Iran.
ali hassanpour, alireza monadi
doaj  

Sialic acid content of low density lipoprotein and its relation to lipid concentrations and metabolism of low density lipoprotein and cholesterol

Journal of Lipid Research, 2000
A low sialic acid content in low density lipoprotein (LDL) has been associated with atherogenicity and coronary artery disease (CAD) in many but not all studies. We investigated associations of the sialic acid-to-apolipoprotein B (apoB) ratio of LDL with
Nina Lindbohm, Helena Gylling, Tatu A. Miettinen   +2 more
doaj   +1 more source

A novel sialic acid-binding adhesin present in multiple species contributes to the pathogenesis of Infective endocarditis.

PLoS Pathogens, 2021
Bacterial binding to platelets is a key step in the development of infective endocarditis (IE). Sialic acid, a common terminal carbohydrate on host glycans, is the major receptor for streptococci on platelets.
Meztlli O Gaytán, Anirudh K Singh, Shireen A Woodiga, Surina A Patel, Seon-Sook An, Arturo Vera-Ponce de León, Sean McGrath, Anthony R Miller, Jocelyn M Bush, Mark van der Linden, Vincent Magrini, Richard K Wilson, Todd Kitten, Samantha J King   +13 more
doaj   +1 more source

Cell surface α2,3-linked sialic acid facilitates Zika virus internalization

Emerging Microbes and Infections, 2019
The emergence of neurotropic Zika virus (ZIKV) raised a public health emergency of global concern. ZIKV can cross the placental barrier and infect foetal brains, resulting in microcephaly, but the pathogenesis of ZIKV is poorly understood.
Chee Wah Tan, Catherine Hong Huan Hor, Swee Sen Kwek, Han Kang Tee, I-Ching Sam, Eyleen L. K. Goh, Eng Eong Ooi, Yoke Fun Chan, Lin-Fa Wang   +8 more
doaj   +1 more source