Results 91 to 100 of about 863,961 (270)
Animal Research and One Health, EarlyView.Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu +8 more
wiley +1 more source
Role of macrophage sialoadhesin in host defense against the sialylated pathogen group B Streptococcus [PDF]
, 2014 Several bacterial pathogens decorate their surfaces with sialic acid (Sia) residues within cell wall components or capsular exopolysaccharides. Sialic acid expression can promote bacterial virulence by blocking complement activation or by engagement of ...
Joshua Olson +11 more
core +1 more source
Modulation of Animal Gut Health by Milk Oligosaccharide
Animal Research and One Health, EarlyView.This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen +7 more
wiley +1 more source
Histoenzymological detection of sialic acids in the rodent salivary glands [PDF]
, 1996 Sections from the major salivary glands of rats and mice were used to locate, characterize and compare sialoglycoconjugates by means of lectin histochemistry, sialidase digestion, periodate oxidation and potassium hydroxide deacetylation.
GABRIELLI, Maria Gabriella +3 more
core +1 more source
Possible Influences of Endogenous and Exogenous Ligands on the Evolution of Human Siglecs
Frontiers in Immunology, 2018 Sialic acids, a group of acidic sugars abundantly expressed in the tissues of deuterostome animals but rarely found in microbes, serve as a “signature of self” for these animals. Cognate sensors for sialic acids include Siglecs, a family of transmembrane
Takashi Angata
doaj +1 more source
From Interferon Signature to the Clinical Landscape: Type I Interferonopathies
Arthritis &Rheumatology, EarlyView.Objective TypeI interferonopathies are heterogeneous diseases driven by dysregulated type I interferon (IFN‐I) signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. The aim of this study was to characterize the clinical, immunologic, genetic, molecular profiles of patients with suspected ...
Ismail Yaz +13 more
wiley +1 more source
Sialic Acids Sweeten a Tumor's Life
, 2014 Item does not contain fulltextOver four decades ago, specific tumor characteristics were ascribed to the increased expression of sialic acid sugars on the surface of cancer cells, and this led to the definition of sialic acids as potential therapeutic ...
Adema, G.J. +3 more
core +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Modern biopharmaceutical manufacturing requires purification platforms capable of processing structurally and functionally diverse products while addressing the challenge of removing persistent and high‐risk host cell proteins (HCPs).
Wenning Chu +23 more
wiley +1 more source
Histochemical properties of sialic acids and antimicrobial substances in canine anal glands
European Journal of Histochemistry, 2011 The functional properties of sialic acids appear to be manifold. Additionally, antimicrobial substances serve as a non-specific defense against microorganisms. In this study, therefore, the localization of sialic acids and antimicrobial substances in the
T. Nara +4 more
doaj +1 more source
RP-UPLC analysis of sialic acids.
, 2022 (A-F) Polysaccharides were acid hydrolyzed and liberated sialic acids were derivatized with DMB for fluorescence detection following separation by RP-UPLC. (G) RP-UPLC of sialic acid monosaccharide standards (5 pmole).
Leandra G. Kingsley (12322872) +5 more
core +1 more source