Results 101 to 110 of about 69,641 (328)
Frontiers in Microbiology, 2016 Viral infections affect millions around the world, sometimes leading to severe consequences or even epidemics. Understanding the molecular dynamics during viral infections would provide crucial information for preventing or stopping the progress of ...
Jaebum Cho +4 more
doaj +1 more source
An Open Receptor-Binding Cavity of Hemagglutinin-Esterase-Fusion Glycoprotein from Newly-Identified Influenza D Virus: Basis for Its Broad Cell Tropism. [PDF]
, 2016 Influenza viruses cause seasonal flu each year and pandemics or epidemic sporadically, posing a major threat to public health. Recently, a new influenza D virus (IDV) was isolated from pigs and cattle. Here, we reveal that the IDV utilizes 9-O-acetylated
Chen, Xi +8 more
core +3 more sources
Advanced Science, EarlyView.ST6GAL1 plays a critical role in tumor progression and immune regulation in colorectal cancer (CRC). Its depletion significantly suppresses the malignant phenotype of CRC cells and enhances the efficacy of anti‐PD‐L1 therapy. High ST6GAL1 expression promotes an immune‐activated tumor microenvironment (TME), characterized by increased infiltration of ...
Ximo Xu +15 more
wiley +1 more source
, 2019 In this review, we summarize the current knowledge concerning the eukaryotic protozoan parasite Leishmania tarentolae, with a main focus on its potential for biotechnological applications.
Klatt, S. +3 more
core +1 more source
The role of cellular adhesion molecules in virus attachment and entry [PDF]
, 2015 As obligate intracellular parasites, viruses must traverse the host-cell plasma membrane to initiate infection. This presents a formidable barrier, which they have evolved diverse strategies to overcome.
Bhella, David
core +1 more source
Identification of TPRA1 as a Novel Receptor and Predictive Biomarker for Oncolytic Virus M1
Advanced Science, EarlyView.This study identifies transmembrane protein adipocyte‐associated 1 (TPRA1) as a novel receptor for oncolytic virus M1 (OVM). TPRA1's ectodomain binds OVM particles, while its intracellular domain facilitates virus internalization, promoting efficient viral entry.
Linyi Hu +20 more
wiley +1 more source
Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+ site [PDF]
, 2018 Many pathogenic bacteria utilise sialic acids as an energy source or use them as an external coating to evade immune detection. As such, bacteria that colonise sialylated environments deploy specific transporters to mediate import of scavenged sialic ...
Abramson, J +20 more
core +3 more sources
Sialic acid on avian erythrocytes
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2019 Understanding variation in physiological traits across taxa is a central question in evolutionary biology that has wide-ranging implications in biomedicine, disease ecology, and environmental protection. Sialic acid (Sia), and in particular, 5-N-acetylneuraminic acid (Neu5Ac), is chemically bound to galactose and the underlying glycan via α2-3 or α2-6 ...
Mark D. Jankowski +5 more
openaire +2 more sources
DePerio: Deep Learning‐Based Oral Inflammatory Load Quantification for Periodontal Applications
Advanced Intelligent Systems, EarlyView.a) Inflammation and oral polymorphonuclear neutrophil (oPMN) Migration: Dental plaque accumulation leads to inflammation, prompting white blood cells (WBCs), particularly oPMNs, to migrate from blood vessels through the gingival epithelium into the oral cavity.
Fatemeh Soheili +9 more
wiley +1 more source
Studying Lactoferrin N-Glycosylation. [PDF]
, 2017 Lactoferrin is a multifunctional glycoprotein found in the milk of most mammals. In addition to its well-known role of binding iron, lactoferrin carries many important biological functions, including the promotion of cell proliferation and ...
Barile, Daniela +4 more
core +3 more sources