Results 141 to 150 of about 70,452 (316)
Engineering antibodies with cancer‐associated binding sites
BMEMat, EarlyView.This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian +4 more
wiley +1 more source
Differential lectin binding patterns in the oviductal ampulla of the horse during oestrus [PDF]
, 2005 We investigated the oligosaccharide sequence of glycoconjugates, mainly sialoglycoconjugates, in the horse oviductal ampulla during oestrus by means of lectin and pre-lectin methods such as the KOH-neuraminidase procedure to remove sialic acid ...
Acone, Franca +7 more
core
Isolation of Sialic Acid from Brain Gangliosides. [PDF]
, 1955 Lars Svennerholm +3 more
openalex +1 more source
Biotechnology Progress, EarlyView.Abstract We present the first use of a bioengineered mammalian transposase system derived from Myotis lucifugus (bMLT) for integration of expression vectors into the CHO genome, focusing on GFP and trastuzumab production. Initially, CHO‐K1 cells are transfected with a GFP reporter and varying amounts of bMLT DNA or mRNA.
Nicolas Marx +10 more
wiley +1 more source
Modeling of the formation of short-chain acids in propane flames [PDF]
arXiv, 2009 In order to better understand their potential formation in combustion systems, a detailed kinetic mechanism for the formation of short-chain monocarboxylic acids, formic (HCOOH), acetic (CH3COOH), propionic (C2H5COOH) and propenic (C2H3COOH)) acids, has been developed. Simulations of lean (equivalence ratios from 0.9 to 0.48) laminar premixed flames of
arxiv
Isolation of Sialic Acid from Gangliosides. [PDF]
, 1955 Gunnar Blix, Lars Odin
openalex +1 more source
Amyloid‐Related Imaging Abnormality (ARIA) Beyond the APOE‐ε4 Allele
Chronic Diseases and Translational Medicine, EarlyView.Mechanism of action of monoclonal antibodies targeting Aβ in the treatment of AD. (A) Targets of various mAbs. (B) Mechanism of monoclonal antibody‐mediated clearance of Aβ. mAbs facilitate the clearance of Aβ by enhancing microglial‐mediated phagocytosis through the upregulation of TREM2 expression.
Valentinus Besin +5 more
wiley +1 more source
Frontiers in Immunology, 2016 Interactions with receptors for the Fc region of IgG (FcγRs) have been shown to contribute to the in vivo protection against influenza A viruses provided by broadly neutralizing antibodies (bnAbs) that bind to the viral hemagglutinin (HA) stem.
Freek Cox
doaj +1 more source
Chemistry – A European Journal, Volume 31, Issue 16, March 17, 2025.A new simple approach for the exquisitely stereo‐controlled introduction of the C‐3 equatorial fluorine on neuraminic acid derivatives by incorporation of steric bulk at C‐4. Through this size‐controlled method, we have elaborated a novel synthetic route that exclusively produces the potent anti‐influenza drug candidate; 2,3‐difluoro‐zanamivir analogue
Ibrahim M. El‐Deeb, Mark von Itzstein
wiley +1 more source
Dendritic Cells: a Spot on Sialic Acid
Frontiers in Immunology, 2013 Glycans decorating cell surface and secreted proteins and lipids occupy the juncture where critical host-host and host-pathogen interactions occur. The role of glycan epitopes in cell-cell and cell-pathogen adhesive events is already well-established ...
Hélio João Crespo +3 more
doaj +1 more source