Results 141 to 150 of about 69,641 (328)

Development of an Artificial Intelligence Verification System Model for Clinical Biochemistry Laboratories Using Machine Learning

open access: yesiLABMED, EarlyView.
The constructed AI verification system performed excellently in terms of accuracy and efficiency. This study provides a new solution for the intelligent verification of clinical biochemistry laboratories and has certain application value. ABSTRACT Background With the exponential growth of testing samples in clinical biochemistry laboratories ...
Lin Zhu   +12 more
wiley   +1 more source

Dendritic Cells: a Spot on Sialic Acid

open access: yesFrontiers in Immunology, 2013
Glycans decorating cell surface and secreted proteins and lipids occupy the juncture where critical host-host and host-pathogen interactions occur. The role of glycan epitopes in cell-cell and cell-pathogen adhesive events is already well-established ...
Hélio João Crespo   +3 more
doaj   +1 more source

Terminology for sialic acids [PDF]

open access: yesBiochemical Journal, 1983
Henry B. F. Dixon, Athel Cornish-Bowden
openaire   +3 more sources

Cytocompatible Enzymatic Hydrogelation of Phenylboronic Acid‐Alginate via H2O2‐Triggered Deboronation

open access: yesMacromolecular Materials and Engineering, EarlyView.
This study develops a hydrogelation method for preparing hydrogels from precursors containing polymer‐PBA and HRP via H2O2‐triggered deboronation and subsequent enzymatic crosslinking. This hydrogelation method can impart dynamic properties to HRP‐mediated hydrogelation without any additives, thereby demonstrating the potential of this hydrogelation ...
Ryota Goto, Shinji Sakai
wiley   +1 more source

Diacetylene‐Functionalized Glycan Mimetics for Receptor‐Mediated Cluster Imprinting in Model Membranes

open access: yesMacromolecular Rapid Communications, EarlyView.
Diacetylene‐containing glycan mimetics cluster upon selective lectin binding in GUVs. Subsequent irradiation leads to the formation of fluorescent polymer clusters, while non‐clustered glycan mimetics remain unaffected in the membrane. ABSTRACT The glycocalyx, a dense layer of glycoproteins and glycolipids on eukaryotic cells, is essential for cellular
Luca‐Cesare Blawitzki   +5 more
wiley   +1 more source

Pancreatic cancer-associated fibroblasts modulate macrophage differentiation via sialic acid-Siglec interactions

open access: yesCommunications Biology
Despite recent advances in cancer immunotherapy, pancreatic ductal adenocarcinoma (PDAC) remains unresponsive due to an immunosuppressive tumor microenvironment, which is characterized by the abundance of cancer-associated fibroblasts (CAFs).
Kelly Boelaars   +22 more
doaj   +1 more source

Protein glycosylation in lung cancer from a mass spectrometry perspective

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi   +2 more
wiley   +1 more source

Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley   +1 more source

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