Results 161 to 170 of about 5,067,072 (323)

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

open access: yesSmall, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti   +5 more
wiley   +1 more source

Sialic acids on B cells are crucial for their survival and provide protection against apoptosis. [PDF]

open access: yesProc Natl Acad Sci U S A, 2022
Linder AT   +7 more
europepmc   +1 more source

Biomaterial‐Based Emergency Intervention for Secondary Spinal Cord Injury

open access: yesSmall Science, EarlyView.
Emergency intervention using advanced biomaterials targets key pathological mechanisms to block secondary spinal cord injury (SCI) by inhibiting inflammation, reducing excitotoxicity, restoring the blood−spinal cord barrier, and limiting scar formation, which provides significant neural protection and promotes neural regeneration, offering promising ...
Jincheng Li   +5 more
wiley   +1 more source

The Sialic Acids

open access: hybrid, 1962
George W. Jourdian, Saul Roseman
openalex   +1 more source

Tailored Metal‐Organic Framework‐Based Enzyme Hybrids: Immobilization Strategies, Improved Performance, and Biological Applications

open access: yesSmall Science, EarlyView.
Metal‐organic frameworks (MOFs) offer versatile platforms for enzyme immobilization to overcome their inherent fragility. However, challenges such as restricted conformation and mass transfer limitations remain. Advances in precise MOF design can help overcome these obstacles, expanding their applicability across diverse fields, highlighting the ...
Xiang Xu   +4 more
wiley   +1 more source

Synthesis of Boronic Acid‐Functionalized Core–Shell Mesoporous Silica–TiO2 Nanocomposite for Specific Enrichment of Glycopeptides From Biological Samples

open access: yesSmall Methods, EarlyView.
The schematic illustrates a workflow showing the current investigation using a boronic acid‐functionalized core–shell mesoporous silica‐TiO₂ (CSMS@TiO₂‐GLYMO‐APB) for N‐glycopeptide enrichment from biological samples, involving trypsin digestion, enrichment, deglycosylation with PNGase F, and subsequent mass spectrometry (MALDI‐TOF MS and Nano‐LC‐MS/MS)
Mohamed Adly Gab‐Allah   +8 more
wiley   +1 more source

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