Results 161 to 170 of about 69,641 (328)

Diversity of sialic acids and sialoglycoproteins in gametes and at fertilization. [PDF]

open access: yesFront Cell Dev Biol, 2022
Fliniaux I   +9 more
europepmc   +1 more source

Enhanced Separation of Intact Proteins and Proteoforms by CZE‐MS Using Sulfobetaine‐Modified Poly(α‐L‐lysine)‐Based Multilayer Coatings for EOF Adjustment

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Mass spectrometry–based top‐down protein analysis requires efficient separation. In the context of proteoform analysis, capillary zone electrophoresis (CZE) is very valuable. The resolution of two peaks in CZE can be increased when the absolute mobility of the counter‐directed electroosmotic flow (EOF) is close to the effective mobility of the
Alisa Höchsmann   +8 more
wiley   +1 more source

The Thiobarbituric Acid Assay of Sialic Acids

open access: yesJournal of Biological Chemistry, 1959
Publisher Summary This chapter discusses the different aspects of thiobarbituric acid assay of sialic acid. Periodate oxidation of the neuraminic acid backbone of sialic acids results in the formation of β -formylpyruvic acid from carbon atoms 1 to 4.
openaire   +3 more sources

Expanding the Reach of Membrane Protein–Ligand Interaction Studies Through the Integration of Mass Spectrometry and Membrane Mimetics

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Mass spectrometry (MS) offers robust, label‐free approaches for characterizing ligand–protein interactions through two main strategies: affinity‐based and stability‐based assays. However, their application to membrane proteins (MPs)—a major class of drug targets—has been limited by challenges such as structural complexity, low native ...
Jonathon C. Lambos   +3 more
wiley   +1 more source

Cloning of hemagglutinin (HA) protein of influenza A virus - Potential for sialic acid linkage discrimination [PDF]

open access: yes, 2007
The initial step in infection of a cell by influenza A virus is the attachment of a virus particle to the target cell. This is accomplished by interaction of a glycoprotein, hemagglutinin (HA), found on the surface of the viral lipid membrane with cell ...
O'Connor, Brendan, Szczepaniak, Jakub
core  

On Serum Sialic Acid Content

open access: bronze, 1955
Yoshiharu Saito   +2 more
openalex   +2 more sources

Synergies in Self‐Assembly—From Supramolecular Polymers to Defined Hierarchical Superstructures

open access: yesJournal of Polymer Science, EarlyView.
Shaping supramolecular polymers built from molecular building blocks into superstructures with defined dimensions. Synergies within supramolecular architectures such as chirality or an additional second orthogonal driving force that does not interfere with the central supramolecular motif facilitate the confinement of the growth of these ...
Klaus Kreger   +2 more
wiley   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

open access: yesSmall, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti   +5 more
wiley   +1 more source

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