ABSTRACT This review provides an in‐depth exploration of capillary electrophoresis–mass spectrometry (CE–MS) in biomolecular research from 2020 to 2024. CE–MS emerges as a versatile and powerful tool due to its numerous advantages, facilitating the analysis of various biomolecules, including proteins, peptides, oligonucleotides, and other metabolites ...
Laura Pont+2 more
wiley +1 more source
Natural selection and genetic variation in a promising Chagas disease drug target: Trypanosoma cruzi trans-sialidase [PDF]
Rational drug design is a powerful method in which new and innovative therapeutics can be designed based on knowledge of the biological target aiming to provide more efficacious and responsible therapeutics.
Gallant, Joseph P.
core +1 more source
Linguistic mechanism of the evolution of amino acid frequencies and genomic GC content [PDF]
Much information is stored in amino acid composition of protein and base composition of DNA. We simulated the evolution of amino acid frequencies and genomic GC content by a linguistic model. It is showed that the evolution of genetic code determines the evolution of amino acid frequencies and genomic GC content.
arxiv
The influence of sialic acid residues on the ability of glycoproteins toi nteract electrostatically with chondromucoprotein [PDF]
Anderson Aj
openalex +1 more source
Tumor Diagnosis and Treatment Based on Stimuli‐Responsive Aggregation of Gold Nanoparticles
This review summarizes the current strategies for inducing gold nanoparticles aggregation and its advances in tumor diagnosis and treatment. The authors hope this review can provide a valuable reference for the further development of AuNPs clinical applications.
Xiaowei Chang, Huaiyu Wang, Xin Chen
wiley +1 more source
Diversity of sialic acids and sialoglycoproteins in gametes and at fertilization. [PDF]
Fliniaux I+8 more
europepmc +1 more source
Genetic Code Table: A note on the three splittings into amino acid classes [PDF]
This note represents the further progress in understanding the determination of the genetic code by Golden mean (Rakocevic, 1998). Three classes of amino acids that follow from this determination (the 7 "golden" amino acids, 7 of their complements, and 6 non-complements) are observed now together with two further possible splittings into 4 x 5 and 5 x ...
arxiv
Biosynthesis of intestinal mucins. Sialic acids of sheep colonic epithelial mucin [PDF]
P. W. Kent, P. W. Draper
openalex +1 more source
Sialic Acids on Tumor Cells Modulate IgA Therapy by Neutrophils via Inhibitory Receptors Siglec-7 and Siglec-9. [PDF]
Chan C+8 more
europepmc +1 more source
Partial characterization of the sialic acid-free forms of α1-acid glycoprotein from human plasma [PDF]
Karl Schmid+4 more
openalex +1 more source