Results 71 to 80 of about 5,067,072 (323)

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

open access: yesAdvanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi   +4 more
wiley   +1 more source

An Anti‐Myd88 Peptide Synergistically Enhances the Anti‐Inflammatory Effects of Extracellular Vesicles from Naïve Umbilical Cord MSC or HEK293F CD24 Overexpressing Cells

open access: yesAdvanced Materials Interfaces, EarlyView.
This study confirms that extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) or HEK293F cells overexpressing CD24 have anti‐inflammatory effects in macrophages and monocytes. Further loading either of these EVs with an anti‐Myd88 peptide synergistically enhanced the anti‐inflammatory effects of the EVs.
Burçin İrem Abas   +6 more
wiley   +1 more source

The Sialic Acid Binding Activity of Human Parainfluenza Virus 3 and Mumps Virus Glycoproteins Enhances the Adherence of Group B Streptococci to HEp-2 Cells

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
In the complex microenvironment of the human respiratory tract, different kinds of microorganisms may synergistically interact with each other resulting in viral-bacterial co-infections that are often associated with more severe diseases than the ...
Jie Tong   +6 more
doaj   +1 more source

Sialic acids, sialoconjugates and enzymes of their metabolism in fungi

open access: yesBiotechnology & Biotechnological Equipment, 2021
Sialic acids (Sia) represent a set of derivatives of nine-carbon sugar neuraminic acid that occupy a terminal position in oligosaccharide chains located on the surface of cells. They are very important for several physiological and pathological processes,
Rumyana Eneva   +4 more
doaj   +1 more source

Biological function of sialic acid and sialylation in human health and disease

open access: yesCell Death Discovery
Sialic acids are predominantly found at the terminal ends of glycoproteins and glycolipids and play key roles in cellular communication and function. The process of sialylation, a form of post-translational modification, involves the covalent attachment ...
Wengen Zhu   +3 more
semanticscholar   +1 more source

Unified Theory of Bacterial Sialometabolism: How and Why Bacteria Metabolize Host Sialic Acids

open access: yesISRN Microbiology, 2013
Sialic acids are structurally diverse nine-carbon ketosugars found mostly in humans and other animals as the terminal units on carbohydrate chains linked to proteins or lipids.
E. Vimr
semanticscholar   +1 more source

Assay System Based on Metabolic Glycoengineering‐Enabled Click Chemistry for the Efficient Evaluation of Complement‐Regulatory Peptide Coatings on Endothelial Cells

open access: yesAdvanced Materials Interfaces, EarlyView.
Metabolic glycoengineering combined with click chemistry efficiently immobilizes clickable factor H (FH)‐binding peptides onto endothelial cell surfaces, creating stable, uniform coatings that recruit FH and enhance resistance to complement‐mediated inflammation.
Jannes Felsch   +7 more
wiley   +1 more source

ST6GAL1‐Mediated Sialylation Stabilizes PD‐L1 and Drives Immunosuppressive Tumor Microenvironment in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
ST6GAL1 plays a critical role in tumor progression and immune regulation in colorectal cancer (CRC). Its depletion significantly suppresses the malignant phenotype of CRC cells and enhances the efficacy of anti‐PD‐L1 therapy. High ST6GAL1 expression promotes an immune‐activated tumor microenvironment (TME), characterized by increased infiltration of ...
Ximo Xu   +15 more
wiley   +1 more source

Analysis of the changes in expression levels of sialic acid on influenza-virus-infected cells using lectin-tagged polymeric nanoparticles

open access: yesFrontiers in Microbiology, 2016
Viral infections affect millions around the world, sometimes leading to severe consequences or even epidemics. Understanding the molecular dynamics during viral infections would provide crucial information for preventing or stopping the progress of ...
Jaebum Cho   +4 more
doaj   +1 more source

A Glycoproteome Data Mining Strategy for Characterizing Structural Features of Altered Glycans with Thymic Involution

open access: yesAdvanced Science, EarlyView.
This study presents a comprehensive data mining strategy for in‐depth extraction of overall and altered glycan features from structural and site‐specific glycoproteome data across various biomedical samples. The strategy enables the uncovery of four major altered glycan features associated with thymic involution and reveals their coordinated ...
Zhida Zhang   +11 more
wiley   +1 more source

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