Results 81 to 90 of about 61,653 (191)

Expression of sialic acids and other nonulosonic acids in Leptospira [PDF]

open access: yes, 2012
BackgroundSialic acids are negatively charged nine carbon backbone sugars expressed on mammalian cell surfaces. Sialic acids are part of a larger family of nonulosonic acid (NulO) molecules that includes pseudaminic and legionaminic acids.
Lewis, Amanda L   +3 more
core   +3 more sources

Possible Influences of Endogenous and Exogenous Ligands on the Evolution of Human Siglecs

open access: yesFrontiers in Immunology, 2018
Sialic acids, a group of acidic sugars abundantly expressed in the tissues of deuterostome animals but rarely found in microbes, serve as a “signature of self” for these animals. Cognate sensors for sialic acids include Siglecs, a family of transmembrane
Takashi Angata
doaj   +1 more source

Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+ site [PDF]

open access: yes, 2018
Many pathogenic bacteria utilise sialic acids as an energy source or use them as an external coating to evade immune detection. As such, bacteria that colonise sialylated environments deploy specific transporters to mediate import of scavenged sialic ...
Abramson, Jeff,   +21 more
core   +3 more sources

Histochemical properties of sialic acids and antimicrobial substances in canine anal glands

open access: yesEuropean Journal of Histochemistry, 2011
The functional properties of sialic acids appear to be manifold. Additionally, antimicrobial substances serve as a non-specific defense against microorganisms. In this study, therefore, the localization of sialic acids and antimicrobial substances in the
T. Nara   +4 more
doaj   +1 more source

Presence of N-acetylneuraminic acid in the lung during postnatal development

open access: yesEuropean Journal of Histochemistry, 2020
Sialic acids, particularly N-acetylneuraminic acid (Neu5Ac), are present as terminal components of rich and complex oligosaccharide chains, which are termed glycans, and are exhibited on the cell surfaces, especially on epithelial cells.
Maria de Fátima Martins   +3 more
doaj   +1 more source

Sialic acid utilization by Cronobacter sakazakii [PDF]

open access: yes, 2013
Background: The Cronobacter genus is composed of seven species, and can cause infections in all age groups. Of particular concern is C. sakazakii, as this species is strongly associated with severe and often fatal cases of necrotizing enterocolitis and ...
Forsythe, S   +3 more
core   +1 more source

One-way trip: Influenza virus' adaptation to gallinaceous poultry may limit its pandemic potential [PDF]

open access: yes, 2014
We hypothesise that some influenza virus adaptations to poultry may explain why the barrier for human-to-human transmission is not easily overcome once the virus has crossed from wild birds to chickens.
Alexander   +101 more
core   +2 more sources

Changes in the Serum and Tissue Levels of Free and Conjugated Sialic Acids, Neu5Ac, Neu5Gc, and KDN in Mice after the Oral Administration of Edible Bird’s Nests: An LC–MS/MS Quantitative Analysis

open access: yesSeparations
Edible bird’s nests have a variety of biological activities, the main components of which are sialic acids. Sialic acids are a group of nine-carbon N-acetylated derivatives of neuraminic acid containing a keto group at position C2 and play important ...
Meng-Hua Wang   +5 more
doaj   +1 more source

Effects of histamine and sodium hypochlorite on prooxidand state in the rats erytrocytes

open access: yesCurrent Issues in Pharmacy and Medical Sciences, 2020
We studied the simultaneous influence of histamine and sodium hypochlorite (SH) on lipid peroxidation processes, as well as the level of structural changes in membranes (via the content of sialic acid) in rat erythrocytes.
Harasym Nataliya   +2 more
doaj   +1 more source

A novel family of bacterial sialic acid binding adhesins? [PDF]

open access: yes, 2020
of Distinction at Nationwide Children's Annual Research RetreatThird place in Biomedical Sciences at the Denman Undergraduate Research ForumPlatelet binding is a critical step in the development of Infective Endocarditis (IE), an infection of the ...
Patel, Surina
core  

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