Results 91 to 100 of about 26,062 (215)

New insights into the immunomodulatory potential of sialic acid on monocyte-derived dendritic cells

Cancer Immunology, Immunotherapy
Sialic acids at the cell surface of dendritic cells (DCs) play an important immunomodulatory role, and their manipulation enhances DC maturation, leading to heightened T cell activation.
Zélia Silva, João Amorim Rabaça, Vanessa Luz, Rita Adubeiro Lourenço, Mariolina Salio, Alexandra Couto Oliveira, Pedro Bule, Sebastian Springer, Paula Alexandra Videira   +8 more
doaj   +1 more source

Relationship between Vaginal Sialidase Levels with Threatened of Preterm Labour

Indonesian Journal of Obstetrics and Gynecology, 2018
Objective: To investigate the association between vaginal sialidase levels and threatened of preterm labor. Methods: A cross sectional study design was used.
Bambang Sulistyo, Najoan N Warouw, Eddy Suparman   +2 more
doaj   +1 more source

PREDICTOR: A Non‐Enzymatic Catalytic Cascade Tool for in Situ Visualization of Small Extracellular Vesicle Surface glycoRNAs

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
PREDICTOR, a non‐enzymatic catalytic circuit for imaging trace glycoRNAs on sEVs, reveals that glycoRNAs abundance negatively correlates with tumour malignancy and is functionally important for sEVs uptake by macrophages ABSTRACT Glycosylated RNAs (glycoRNAs) are membrane‐displayed RNA‐glycan conjugates, but quantitative in situ analysis of low ...
Shuang Xie, Ben Niu, Ruijia Deng, Liu Feng, Zuowei Xie, Shuang Zhao, Hongzhao Yang, Meilin Gong, Jing Sheng, Ligai Zhang, Yan Pi, Ningtao Cheng, Ming Chen, Kai Chang   +13 more
wiley   +1 more source

A new sialidase mechanism: bacteriophage K1F endo-sialidase is an inverting glycosidase.

The Journal of biological chemistry, 2009
Bacteriophages specific for Escherichia coli K1 express a tailspike protein that degrades the polysialic acid coat of E. coli K1 that is essential for bacteriophage infection. This enzyme is specific for polysialic acid and is a member of a family of endo-sialidases.
Morley, Thomas J., Willis, Lisa M., Whitfield, Chris, Wakarchuk, Warren W., Withers, Stephen G.   +4 more
openaire   +2 more sources

Sequence‐Based and Functional Analysis for the Discovery of N‐Glycan Degrading Glycosidases From the Microbial Metagenome of the Infant Gut

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
This research offers valuable understanding of how N‐glycans are broken down by the gut microbiota of infants, focusing on glycoside hydrolase families GH2, GH20, and GH18. It reveals that the gut microbiota of breastfed infants has a diverse array of genes coding for these enzymes.
Irene Boscá‐Sánchez, Jesús Rodríguez‐Díaz, María J. Yebra   +2 more
wiley   +1 more source

Rag GTPases are cardioprotective by regulating lysosomal function. [PDF]

, 2014
The Rag family proteins are Ras-like small GTPases that have a critical role in amino-acid-stimulated mTORC1 activation by recruiting mTORC1 to lysosome.
Guan, Kun-Liang, Jewell, Jenna L, Kim, Young Chul, Mo, Jung-Soon, Park, Hyun Woo, Russell, Ryan C, Sadoshima, Junichi, Sciarretta, Sebastiano, Wu, Xiaohui   +8 more
core   +2 more sources

Trypanosoma rangeli sialidase: lack of activity in stocks from Panama and other regions

Memorias do Instituto Oswaldo Cruz, 2005
A total of 33 crude and cloned Trypanosoma rangeli stocks found as natural infections in human from Panama and other endemic areas of Central and South America were evaluated as producers of sialidase (SA) activity through the MU-NANA fluorescence test ...
Octavio E Sousa, Maritza Lombardo, Azael Saldaña   +2 more
doaj   +1 more source

Trans-sialidase from Trypanosoma cruzi enhances the adhesion properties and fibronectin-driven migration of thymocytes [PDF]

, 2013
In experimental Trypanosoma cruzi infections, severe thymic atrophy leads to release of activated CD4+CD8+ double-positive (DP) T cells to the periphery.
Bellio, Maria, Bottasso, Oscar Adelmo, Caruso Neves, Celso, Dias, Wagner B., Farias de Oliveira, Désio Aurélio, Freire de Lima, Célio Geraldo, Meis, Juliana de, Morrot, Alexandre, Nardy, Ana Flávia F.R., Oliveira, Isadora de Araújo, Penha, Luciana, Perez, Ana Rosa, Pinheiro, Ana Acácia, Savino, Wilson, Silva Filho, Joao Luiz da, Takiya, Christina Maeda, Todeschini, Adriane   +16 more
core   +1 more source

Sialidase Activity in Transformed Cells

Journal of Biological Chemistry, 1973
Abstract Sialidase activity, ganglioside patterns, and total cellular sialic acid content were determined for normal and transformed hamster cells in tissue culture. Sialidase activity toward added extracellular disialo- and trisialoganglioside substrate was found in all transformed cell lines studied.
C L, Schengrund, R N, Lausch, A, Rosenberg   +2 more
openaire   +2 more sources

Bacterial sialoglycosidases in Virulence and Pathogenesis

Pathogens, 2019
Human oral microbiome and dysbiotic infections have been recently evidently identified. One of the major reasons for such dysbiosis is impairment of the immune system.
Preethi Sudhakara, Iyappan Sellamuthu, A. Wilson Aruni   +2 more
doaj   +1 more source