Results 101 to 110 of about 20,212 (212)

Sialidase Specificity Determined by Chemoselective Modification of Complex Sialylated Glycans

, 2016
Sialidases hydrolytically remove sialic acids from sialylated glycoproteins and glycolipids. Sialidases are widely distributed in nature and sialidase-mediated desialylation is implicated in normal and pathological processes. However, mechanisms by which
Jennifer J. Kohler (234258), Randy B. Parker (2041630), Janet E. McCombs (2041633)   +2 more
core   +1 more source

Characterization of sialidase complementing strains.

, 2013
Panel A, PCR confirmation of the construction of isogenic sialidase null mutant and complementing strains. Using DNA isolated from BMC206, PCR assays using internal sialidase gene primers amplified the expected wild-type nanJ, nanI and nanH products of ...
Bruce A. McClane (45208), Jihong Li (45207), Jianming Chen (29410), Sameera Sayeed (338179), Susan Robertson (338180)   +4 more
core   +1 more source

Cytosolic sialidase in developing rat forebrain

, 1982
The nature and developmental profile of the soluble sialidase of rat forebrain were studied from birth to 150 days. Forebrain was extracted by two procedures, one (mild) preserving, the other (drastic) destroying nerve endings.
A.Fiorilli, A.Lombardo, G.Tettamanti, G.Goi, A. Preti, B.Venerando   +5 more
core   +1 more source

The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents [PDF]

, 2005
Campetella, O., Rooijen, N. van, Tribulatti, M.V., Mucci, J., Leguizamon, M.S., van Rooijen, N.   +5 more
core   +1 more source

The role of sialidases in the pathogenesis of bacterial vaginosis and their use as a promising pharmacological target in bacterial vaginosis

Frontiers in Cellular and Infection Microbiology
Bacterial vaginosis (BV) is an infection of the genital tract characterized by disturbance of the normally Lactobacilli-dominated vaginal flora due to the overgrowth of Gardnerella and other anaerobic bacteria.
Liuyan Chen, Jiayue Li, Bingbing Xiao
doaj   +1 more source

Endothelial cell signalling induced by trans-sialidase from Trypanosoma cruzi.

, 2007
International audienceThe protozoan responsible for Chagas' disease, Trypanosoma cruzi, expresses on its surface an unusual trans-sialidase enzyme thought to play an important role in host-parasite interactions.
Fajardo, Fernanda D, Girard, Murielle F, José O. Previato, Aurelio V. Graça-Souza, Leonardo Freire-de-Lima, Adriane R. Todeschini, Freire-De-Lima, Leonardo, Murielle F. Girard, Dias, Wagner B, Wagner B. Dias, Todeschini, Adriane R, Fabiana Vieira, Mendonça-Previato, Lucia, Graça-Souza, Aurelio V, Vieira, Fabiana, Bernard Bouteille, Previato, José O, Lucia Mendonça-Previato, Bouteille, Bernard, Fernanda D. Fajardo   +19 more
core   +1 more source

Combined occurrence of trypanosomal sialidase/trans-sialidase activities and leishmanial metalloproteinase gene homologues in Endotrypanum sp.

, 1994
Endotrypanum (order Kinetoplastida: family Trypanosomatidae) is a parasite of forest dwelling tree sloths (Edentata: genera Choleopus and Bradypus). Unique among the haemoflagellates, this protozoan has an intraerythrocytic phase in the mammalian host ...
Tomlinson, Stephen, Pontes-de-Carvalho, Lain Carlos, Paul, Simon, Acosta, Enrique Medina   +3 more
core   +1 more source

THE EFFECTS OF HYPOMORPHIC SIALIDASE EXPRESSION ON ATHEROSCLEROSIS [PDF]

, 2012
Atherosclerosis is a complex multifactorial disease which is an important risk factor for morbidity and mortality related to coronary heart disease and stroke in humans.
Yang, Abraham E.
core  

Distribution of Sialidase Activity and the Role of Sialidase in the Brain

Trends in Glycoscience and Glycotechnology, 2012
Akira Minami, Takashi Suzuki
openaire   +2 more sources

Modulating the sialic acid content of endothelial cells affects their adhesion and barrier permeability. [PDF]

Sci Rep
Müller PM, Weilepp L, Bork K, Horstkorte R, Gesper A.   +4 more
europepmc   +1 more source