Results 111 to 120 of about 4,367 (168)

Glycosylated extracellular matrix drives immune suppression by modulating macrophage-T cell crosstalk in triple-negative breast cancer. [PDF]

open access: yesNat Commun
Tarantola L   +25 more
europepmc   +1 more source

Unraveling the glyco-immunity nexus in pancreatic cancer. [PDF]

open access: yesMol Cancer
Rajesh C, Cummings RD, Radhakrishnan P.
europepmc   +1 more source
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Sialyl-Lewis x and Sialyl-Lewis a are associated with MUC1 in human endometrium

Glycoconjugate Journal, 1996
Endometrial epithelial cells express MUC1 with increased abundance in the secretory phase of the menstrual cycle, when embryo implantation occurs. MUC1 is associated with the apical surface of epithelial cells and is also secreted, being detectable in uterine fluid at elevated levels in the implantation phase.
Hey, Neil A.   +1 more
openaire   +3 more sources

Synthesis of Sialyl Lewis X Analogues

Journal of Carbohydrate Chemistry, 1996
Sialyl Lewis X (SLe) analogs 2a and 2b were synthesised, where the N-acetyl-D-glucose and the D-galactose units of SLe 1 were replaced with an alkyl and a heteroalkyl spacer. Sulphate ester 6i was also synthesised from alcohol 6b and chlorosulphonic acid.
Dekany, Gyula   +3 more
openaire   +2 more sources

Synthesis of Sialyl Lewis x Analogues 2

Journal of Carbohydrate Chemistry, 1997
Sialyl Lewis X (SLe analogues) containing ß-L-fucopyranosyl residues with an alkyl [-(CH)-] (1a), a heteroalkyl [-(CH)-O-(CH)-] (1b) or a heterocycloalkyl [-2-cyclohexyl-O-(CH)-] (2a) moiety were synthesised by silver ion promoted glycosylation. Further analogues where sialic acid was replaced by a second ß-L-fucopyranosyl (3a, 3b) or hydrogensulphate ...
Dekany, Gyula   +3 more
openaire   +2 more sources

Core saccharide dependence of sialyl Lewis X biosynthesis

Glycoconjugate Journal, 2008
The sialyl-Lewis X (SLe(x)) determinant is important in leukocyte extravasation, metastasis and bacterial adhesion. The role of the protein, N-glycan and O-glycan core structures for the biosynthesis of SLe(x) in vivo by fucosyltransferases (FucTs) is not known.
Jonas, Löfling, Jan, Holgersson
openaire   +2 more sources

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