Results 161 to 170 of about 17,651 (213)
Effects of sialylated oligosaccharides on the N- and O-glycosylation of etanercept in recombinant CHO cells. [PDF]
Appl Microbiol BiotechnolKim TH +7 more
europepmc +1 more source
Total Synthesis of the SJG-2 Glycan: General Strategies for Constructing Sterically Congested Sialylated Glycans. [PDF]
J Am Chem SocSu YY +6 more
europepmc +1 more source
B-cell–independent sialylation of IgG
Proceedings of the National Academy of Sciences of the United States of America, 2016 IgG carrying terminal α2,6-linked sialic acids added to conserved N-glycans within the Fc domain by the sialyltransferase ST6Gal1 accounts for the anti-inflammatory effects of large-dose i.v. Ig (IVIg) in autoimmunity.
Sidney Whiteheart +2 more
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To sialylate, or not to sialylate: that is the question
Trends in Microbiology, 2002Most oropharyngeal pathogens express sialic acid units on their surfaces, mimicking the sialyl-rich mucin layer coating epithelial cells and the glycoconjugates present on virtually all host cell surfaces and serum proteins. Unlike the host's cells, which synthesize sialic acids endogenously, several microbial pathogens use truncated sialylation ...
Eric, Vimr, Carol, Lichtensteiger
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Calculated conformations of sialyl-Lex- and sialyl-Lea-lactones
Bioorganic & Medicinal Chemistry, 1994The minimum energy conformations of the four sterically reasonable SLe(x) and SLe(a) lactones were calculated using the molecular mechanics force-field MM2(91). The tetrasaccharide lactone involving the 3- and 2-position of the Gal moiety was found to be more stable than the 3,4-lactone both for SLe(x) and SLe(a).
U, Ellervik, G, Magnusson
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Aberrant Sialylation in Cancer: Therapeutic Opportunities [PDF]
Cancers, 2022 \ua9 2022 by the author. The surface of every eukaryotic cell is coated in a thick layer of glycans that acts as a key interface with the extracellular environment.
Jennifer Munkley
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Stereoselective α-Sialylation with Sialyl Xanthate and Phenylsulfenyl Triflate as a Promotor
The Journal of Organic Chemistry, 1996Reaction alpha- and beta-xanthates 2 and 3 of sialic acid with glycosyl acceptors 5-8 in the presence phenylsulfenyl triflate (PST) as a promotor in a 2:1 mixture of CH(3)CN/CH(2)Cl(2) at low temperature affords alpha-sialosides in good yield and stereoselectivity. PST is prepared in situ by reacting benzenesulfenyl chloride with silver triflate.
Valeri, Martichonok +1 more
openaire +2 more sources
Journal of Surgical Oncology, 1996
Sialyl Lewis Tn(STN), sialyl Lewis a(CA-9-9), sialyl Lewis a-b-(DU-PAN-2), and sialyl Lewis x(SLX) antigens were immunohistochemically examined in the primary tumor and metastatic lymph nodes in 35 patients with advanced gastric cancer. STN, CA-19-9, DU-PAN-2, and SLX were expressed in 91%, 60%, 31%, and 60% in the primary lesion, and 77%, 54%, 22 ...
Y, Ikeda +5 more
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Sialyl Lewis Tn(STN), sialyl Lewis a(CA-9-9), sialyl Lewis a-b-(DU-PAN-2), and sialyl Lewis x(SLX) antigens were immunohistochemically examined in the primary tumor and metastatic lymph nodes in 35 patients with advanced gastric cancer. STN, CA-19-9, DU-PAN-2, and SLX were expressed in 91%, 60%, 31%, and 60% in the primary lesion, and 77%, 54%, 22 ...
Y, Ikeda +5 more
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The sialylation of plasma lipoproteins
Atherosclerosis, 2001Sialic acids are a family of amino sugars that are commonly found as terminal oligosaccharide residues on glycoproteins and glycolipids. Plasma lipoproteins are sialylated on their apolipoprotein and glycolipid constituents. The function of sialic acid on apolipoproteins is not completely understood but has been associated with secretion, lipid-binding,
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Trifluoroacetamido Substituted Sialyl Donors for the Preparation of Sialyl Galactosides
Australian Journal of Chemistry, 2002Glycosidations of sialyl donor (1a), bearing a trifluoroacetamido group at C5, with partially protected D-galactosyl derivatives afforded (2,3)-linked disaccharides in high yields and excellent stereoselectivities, even when sterically hindered alcohols were used as glycosyl acceptors.
C. De Meo, A. V. Demchenko, G.-J. Boons
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