Results 91 to 100 of about 10,746,438 (360)
Abstract Background While interhospital patient transfers are common, most existing literature centers on transfers to academic medical centers (AMCs) and tertiary/quaternary care hospitals for a higher level of care. With the growing trend of healthcare system consolidation and formation of regional affiliations, many systems now coordinate admissions
Ruby Marr +6 more
wiley +1 more source
Sickle cell disease: Reducing the global disease burden
Sickle cell disease has been largely an invisible global health issue, especially in regions of high incidence mainly due to lack of awareness among both the local health policy makers and the public.
Joy Mburu, I. Odame
semanticscholar +1 more source
Background: Sickle cell disease (SCD) is among the most frequent hereditary disorders globally and its prevalence in Europe is increasing due to migration movements. Summary: The basic pathophysiological event of SCD is polymerization of deoxygenated sickle hemoglobin, resulting in hemolysis, vasoocclusion, and multiorgan damage.
Kunz, Joachim B., Tagliaferri, Laura
openaire +2 more sources
Abstract Background and Objectives Children with medical complexity (CMC) have chronic health conditions often associated with functional limitations. CMC comprise 1%–5% of the pediatric population. In Canada, their care accounts for one‐third of pediatric health spending.
Erin Hessey +25 more
wiley +1 more source
IntroductionNewborn Screening (NBS) is a public health program designed to identify and provide early interventions for infants with genetic disorders such as Sickle Cell Disease (SCD).
Isa Hezekiah A +6 more
doaj +1 more source
Emerging disease-modifying therapies for sickle cell disease
Sickle cell disease afflicts millions of people worldwide and approximately 100,000 Americans. Complications are myriad and arise as a result of complex pathological pathways ‘downstream’ to a point mutation in DNA, and include red blood cell membrane ...
Marcus A. Carden, J. Little
semanticscholar +1 more source
Abstract Introduction Community‐acquired pneumonia (CAP) is a frequent and costly cause of pediatric emergency department (ED) visits and hospitalizations. Previous prognostic tools for CAP are limited by small samples, single‐center or retrospective designs, lack of generalizability to ED settings, lack of biomarkers, or limited objective data.
Todd A. Florin +21 more
wiley +1 more source

