Results 31 to 40 of about 78,171 (294)

Fatal Dengue in Patients with Sickle Cell Disease or Sickle Cell Anemia in Curaçao: Two Case Reports [PDF]

, 2013
Fatal Dengue in Patients with Sickle Cell Disease or Sickle Cell Anemia in Curaçao: Two Case ...
ACE Andrianarisoa, Albert D. M. E. Osterhaus, BEE Martina, D González, D Limonta, DC Rees, E Teruel-López, Eric C. M. van Gorp, Fleur M. Moesker, Fred D. Muskiet, Isaac Gerstenbluth, Jeanne J. Koeijers, JR Bravo, M Gentilini, MA Ware, Pieter L. A. Fraaij, SB Halstead, Scott B. Halstead   +17 more
core   +6 more sources

Drugs for preventing red blood cell dehydration in people with sickle cell disease. [PDF]

, 2016
BACKGROUND: Sickle cell disease is an inherited disorder of hemoglobin, resulting in abnormal red blood cells. These are rigid and may block blood vessels leading to acute painful crises and other complications.
Ballas, Samir K., Nagalla, Srikanth
core   +2 more sources

Prevalence of Haemoglobine s in Araraquara-SP Population.

Revista Brasileira Multidisciplinar - ReBraM /Brazilian Multidisciplinay Journal, 2015
The Sickle Cell Anemia is a genetic hemoglobionopathy, characterized by an alteration in the hemoglobin molecule struture (HbA1), called hemoglobin S (HbS), which causes a distortion in the erythocytes structure, changing from spherical shape to sickle ...
Bruno Rocha de Jesus, Heloise Brait Rin, Elza Regina Manzolli Leite, Amauri Antiquera Leite, Miriane da Costa Gileno   +4 more
doaj   +1 more source

Studies on the Hemoglobin of Cooley's Anemia and Cooley's Trait [PDF]

, 1952
The diseases sickle cell anemia and Cooley's anemia (also known as thalassemia or Mediterranean anemia) have associated with them "minor" or "trait" forms of the disease in which the symptomatology is minimal, and the abnormalities in the red cells are ...
Rich, Alexander
core  

Nutritional status of young children with inherited blood disorders in western Kenya. [PDF]

, 2014
To determine the association between a range of inherited blood disorders and indicators of poor nutrition, we analyzed data from a population-based, cross-sectional survey of 882 children 6–35 months of age in western Kenya.
Ruth, LJ, Suchdev, PS, Sullivan, KM, Tsang, BL, Williams, TN   +4 more
core   +1 more source

Discovery of a Novel DNMT1 Inhibitor with Improved Efficacy in Treating β‐Thalassemia

Advanced Science, EarlyView.
Context of Research: β‐thalassemia affects millions worldwide. DNMT inhibitors are effective HbF‐inducers that benefit patients with β‐thalassemia. Existing DNMT inhibitors are not approved for β‐thalassemia treatment due to dose‐limiting toxicity.What We Find: DMT207 traps DNMT1 into helix‐kinked inactive conformation and enhances its interaction with
Yijie Shen, Jiale Wei, Shibing Tang, Dongliang Wu, Liangyi Zong, Shuyuan Ma, Qing Xiong, Ruijie Gong, Siyuan Xu, Chuxuan Peng, Qin Feng, Songchen Liu, Qitong Liu, Yuhua Ye, Quan Zhao, Cheng Luo, Peng Huang, Zhihai Li, Xiangqian Kong, Xianjiang Lan   +19 more
wiley   +1 more source

Hemorheological risk factors of acute chest syndrome and painful vaso-occlusive crisis in children with sickle cell disease

Haematologica, 2012
Background Little is known about the effects of blood rheology on the occurrence of acute chest syndrome and painful vaso-occlusive crises in children with sickle cell anemia and hemoglobin SC disease.Design and Methods To address this issue, steady ...
Yann Lamarre, Marc Romana, Xavier Waltz, Marie-Laure Lalanne-Mistrih, Benoît Tressières, Lydia Divialle-Doumdo, Marie-Dominique Hardy-Dessources, Jens Vent-Schmidt, Marie Petras, Cedric Broquere, Frederic Maillard, Vanessa Tarer, Maryse Etienne-Julan, Philippe Connes   +13 more
doaj   +1 more source

Genetic variants in the G gamma-globin promoter modulate fetal hemoglobin expression in the Colombian population [PDF]

Genetics and Molecular Biology, 2020
Fetal hemoglobin (HbF) is a determining factor for the development of sickle cell anemia. High HbF levels lower the intensity of symptoms of this disease. HbF levels can vary in patients with sickle cell anemia and individuals without the disease.
Cristian Fong, Yesica Mendoza, Guillermo Barreto   +2 more
doaj   +1 more source

Proteomic Analysis of Golden Sputum Reveals Pulmonary Complement Activation During Acute Chest Syndrome in Children With Sickle Cell Disease

American Journal of Hematology, EarlyView.
ABSTRACT Acute chest syndrome (ACS) is one of the most common severe complications of sickle cell disease (SCD). In recent years, a major role of inflammation and innate immunity has been evidenced, but ACS pathophysiology remains incompletely understood, and therapeutic options are limited.
Slimane Allali, Nabiha Sbeih, Rachel Rignault‐Bricard, Johanna Bruce, Morgane Le Gall, Claire Heilbronner, Noemie de Cacqueray, Sofia Angyalosy, Melissa Taylor, Joséphine Brice, Mariane de Montalembert, Martina Bevacqua, Emilie‐Fleur Gautier, Olivier Hermine, Thiago Trovati Maciel   +14 more
wiley   +1 more source

Comorbidity, Pain, Utilization, and Psychosocial Outcomes in Older versus Younger Sickle Cell Adults: The PiSCES Project [PDF]

, 2017
Background. Patients with SCD now usually live well into adulthood. Whereas transitions into adulthood are now often studied, little is published about aging beyond the transition period. We therefore studied age-associated SCD differences in utilization,
Aisiku, Imoigele P., Bovbjerg, Viktor E., Levenson, James L., McClish, Donna K., Roberts, John D., Roseff, Susan D., Smith, Wally R.   +6 more
core   +4 more sources