Results 1 to 10 of about 1,826,875 (263)

Specifying sickle cell disease interventions: a study protocol of the Sickle Cell Disease Implementation Consortium (SCDIC) [PDF]

BMC Health Services Research, 2018
Background Sickle cell disease (SCD) is an inherited blood disorder that results in a lifetime of anemia, severe pain, and end-organ damage that can lead to premature mortality.
Ana A. Baumann, Steven H. Belle, Aimee James, Allison A. King, the Sickle Cell Disease Implementation Consortium   +4 more
doaj   +3 more sources

Clinical manifestations of sickle cell disease in Africa and its association with foetal haemoglobin parameters [PDF]

Communications Medicine
Background Prevalence of sickle cell disease (SCD) across African countries ranges between 1–3% and contributes up to 7–16% of under-five mortality.
Evans Xorse Amuzu, Florence Urio, Elliot Eli Dogbe, Peter Ponsian, Suraj Yawnumah Abubakar, Chinedu Okeke, Olasinbo Olumuyiwa Balogun, Petronilla Jean Ozumba, Alex Osei-Akoto, Vivian Paintsil, Obiageli Nnodu, Emmanuel Balandya, Julie Makani, Madu Anazoeze, Daniel Ansong, Siana Nkya   +15 more
doaj   +2 more sources

Findings supporting neonatal screening for sickle cell disease: an observational study in Senegal [PDF]

Frontiers in Pediatrics
IntroductionSickle cell disease (SCD) is a major contributor to morbidity and mortality in sub-Saharan Africa, and early detection through neonatal screening can improve outcomes. In Senegal, systematic screening is not yet implemented.
Lucie Petigas, Ndiogou Seck, Ndiogou Seck, Dominique Doupa, Dominique Doupa, Ibrahima Diagne, Ibrahima Diagne, Matthias Roth-Kleiner, Matthias Roth-Kleiner   +8 more
doaj   +2 more sources

Hemodynamic profile of cerebral arteries using transcranial Doppler in children with sickle cell disease compared to children without sickle cell disease: Prospective analytical study [PDF]

BMC Pediatrics
Background Cerebral vasculopathy is a frequent and serious complication of major sickle cell disease syndromes. Transcerebral Doppler (TCD) can detect stenosis of the main arteries at the base of the skull before stroke occurs, and initiate therapy to ...
Patrick Landu Kinkunda, Aliocha Natuhoyila Nkodila, Joël Kashale Mutamba, Orlin Mamona Yindula, Roger Izeidi Gangale, Lilly Mokulayanga, Émeraude Manzombi, Djo Mbo-M. Iyoto, Lys Makwanza, Cynthia Bukumba Minouche, Stéphane Tongo Yanda, Antoine Aundu Molua, Jean Tshibola Mukaya   +12 more
doaj   +2 more sources

Advances in the diagnosis and treatment of sickle cell disease

Journal of Hematology & Oncology, 2022
Sickle cell disease (SCD), which affects approximately 100,000 individuals in the USA and more than 3 million worldwide, is caused by mutations in the βb globin gene that result in sickle hemoglobin production.
A. Brandow, R. Liem
semanticscholar   +1 more source

Associated Factors of Cholelithiasis among Younger Children with Sickle Cell Disease at the National Reference Center for Sickle Cell Disease in Brazzaville, Congo

Anemia, 2023
Introduction. Chronic hemolysis predisposes sickle cell patients to the development of gallstones. Their frequency increases with age, but they may appear early in young children.
Firmine Olivia Galiba Atipo Tsiba, Clément Pacha Mikia, Jennifer Armandine Elira Samba, Jade Vanessa Nziengui Mboumba, Félix Malanda, Clausina Mikolele Ahoui, Alexis Elira Dokekias   +6 more
doaj   +1 more source

Concomitant Presence of Hb Agrinio and - -Med Deletion in a Greek Male Patient with Hemoglobinopathy H: More Severe Phenotype and Literature Review

Hematology Reports, 2023
Hemoglobin (Hb) Agrinio is a rare non-deletional a-globin mutation observed almost exclusively in Greek, Spanish or other Mediterranean families. The clinical manifestations of a carrier of a single Hb Agrinio mutation (single heterozygosity) depend on ...
Michael D. Diamantidis, Stefania Pitsava, Omar Zayed, Ioanna Argyrakouli, Konstantinos Karapiperis, Christos Chatzoulis, Evangelos Alexiou, Achilles Manafas, Evangelos Tsangalas, Konstantinos Karakoussis   +9 more
doaj   +1 more source

Sickle cell disease patients with COVID‐19 in Guadeloupe: Surprisingly favorable outcomes

eJHaem, 2022
We investigate risk factors for hospitalization and difference between sickle cell syndromes in a cohort of COVID‐19 sickle cell disease (SCD) adult patients managed in the Reference Center of Guadeloupe.
Emmanuelle Bernit, Marc Romana, Scylia Alexis‐Fardini, Vanessa Tarer, Pierre‐Marie Roger, Lydia Doumdo, Eléonore Petras, Corine Charneau, Benoit Tressières, Marie Dominique Hardy Dessources, Maryse Etienne‐Julan   +10 more
doaj   +1 more source

Lifetime medical costs attributable to sickle cell disease among nonelderly individuals with commercial insurance

Blood Advances, 2022
Key Points • The nonelderly lifetime burden of total medical costs attributable to sickle cell disease was $1.7 million.• Patients incurred $44 000 in out-of-pocket costs due to sickle cell disease over their nonelderly lifetimes.
Kate M. Johnson, B. Jiao, Scott D. Ramsey, M. Bender, B. Devine, A. Basu   +5 more
semanticscholar   +1 more source

The Effect of COVID-19 on Hemoglobinopathy Patients’ Daily Lives While Quarantined: Four Greek Hospitals’ Experiences

Thalassemia Reports, 2022
During a pandemic, people are fearful of becoming infected with the virus, which causes anxiety, loss of purpose, and depression. This study aimed to evaluate the social and psychological impact, as well as the impact on homecare, of patients with ...
Sophia Delicou, Aikaterini Xydaki, Konstantinos Manganas, Emmanouil Koullias, Loukia Evliati, Chryssoula Kalkana, Michael D. Diamantidis, Achilles Manafas, Marianna Katsatou, Leonidas Roumpatis, Theodoros Aforozis   +10 more
doaj   +1 more source