Results 61 to 70 of about 94,881 (302)

Mechanistic Consequences of Piezo1 Gain‐of‐Function Variants for Decreased Red Cell Survival in Hereditary Xerocytosis

American Journal of Hematology, EarlyView.
Asya Makhro, Rick Huisjes, Elena Seiler, Min Qiao, Marije Bartels, Inga Hegemann, Patrick Eppenberger, Nicole Bender, Isabel Dorn, Anna Bogdanova, Richard van Wijk, Lars Kaestner   +11 more
wiley   +1 more source

Most costly and prevalent reasons for hospitalization in children with medical complexity in Ontario, Canada

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Children with medical complexity (CMC) have chronic health conditions often associated with functional limitations. CMC comprise 1%–5% of the pediatric population. In Canada, their care accounts for one‐third of pediatric health spending.
Erin Hessey, Thaksha Thavam, Sanjay Mahant, Eyal Cohen, Jingqin Zhu, Francine Buchanan, Teresa To, Peter J. Gill, Ontario Pediatric Hospital Care Study Group (OPHCSG) and the Canadian Paediatric Inpatient Research Network (PIRN), Wenjia Chen, Ronald Cohn, Mairead Green, Matt Hall, Kate Langrish, Colin Macarthur, Myla Moretti, Patricia Parkin, Michelle Quinlan, Ann Bayliss, Ronik Kanani, Sean Murray, Catherine Pound, Mahmoud Sakran, Anupam Sehgal, Sepi Taheri, Gita Wahi   +25 more
wiley   +1 more source

Enhancing the Management of Pediatric Sickle Cell Disease by Integrating Functional Evaluation to Mitigate the Burden of Vaso-Occlusive Crises

Journal of Vascular Diseases
Sickle cell disease (SCD) imposes a significant health burden, particularly in low- and middle-income countries where healthcare professionals and resources are scarce.
Paul Muteb Boma, Alain Ali Kaponda, Jules Panda, Bruno Bonnechère   +3 more
doaj   +1 more source

SICKLE CELL DISEASE AND PREGNANCY

Mediterranean Journal of Hematology and Infectious Diseases, 2019
Abstract   Sickle Cell Disease (SCD) is a group of inherited single-gene autosomal recessive disorders caused by the ‘sickle’ gene, which affects haemoglobin structure. Sickle cell anemia is the most common hemoglobinopathy worldwide. The burden of sickle cell disease in pregnancy has been exponentially increasing with more number of women ...
Dipty Jain, Pooja Lodha, Roshan Colah, Prachi Atmapoojya, Prachi Atmapoojya   +4 more
openaire   +4 more sources

Derivation and validation of the Pediatric Community‐Acquired Pneumonia Severity (PedCAPS) score: A prospective cohort study

Journal of Hospital Medicine, EarlyView.
Abstract Introduction Community‐acquired pneumonia (CAP) is a frequent and costly cause of pediatric emergency department (ED) visits and hospitalizations. Previous prognostic tools for CAP are limited by small samples, single‐center or retrospective designs, lack of generalizability to ED settings, lack of biomarkers, or limited objective data.
Todd A. Florin, Ron Reeder, Lilliam Ambroggio, Richard M. Ruddy, Samir S. Shah, Allison Cator, Matthew J. Lipshaw, Geoffrey A. Capraro, Laura F. Sartori, Amy Y. Cheng, Leah Tzimenatos, Patrick S. Walsh, Claudia R. Morris, Chris A. Rees, Son H. McLaren, Tamar R. Lubell, Chari D. Larsen, Justin Moher, Eileen J. Klein, Shubhada Hooli, Nathan Kuppermann, Pediatric Emergency Care Applied Research Network (PECARN) PedCAPS Investigators   +21 more
wiley   +1 more source

Family cord blood banking for sickle cell disease: a twenty-year experience in two dedicated public cord blood banks

Haematologica, 2017
Efforts to implement family cord blood banking have been developed in the past decades for siblings requiring stem cell transplantation for conditions such as sickle cell disease. However, public banks are faced with challenging decisions about the units
Hanadi Rafii, Françoise Bernaudin, Helene Rouard, Valérie Vanneaux, Annalisa Ruggeri, Marina Cavazzana, Valerie Gauthereau, Aurélie Stanislas, Malika Benkerrou, Mariane De Montalembert, Christele Ferry, Robert Girot, Cecile Arnaud, Annie Kamdem, Joelle Gour, Claudine Touboul, Audrey Cras, Mathieu Kuentz, Claire Rieux, Fernanda Volt, Barbara Cappelli, Karina T. Maio, Annalisa Paviglianiti, Chantal Kenzey, Jerome Larghero, Eliane Gluckman   +25 more
doaj   +1 more source

Blame It on My (Arterial) Youth: How Childhood Vascular Morphology Shapes the Risk of Cerebral Vasculopathy in Sickle Cell Disease

American Journal of Hematology, EarlyView.
Thomas Pincez
wiley   +1 more source

Standardised Request and Contrast Consent Forms to Enhance Clinical Learning in Radiography Education

Journal of Medical Radiation Sciences, EarlyView.
This study developed standardised Medical Imaging Suite (MIS) request and contrast consent forms, modelled on real‐world documentation, to enhance student learning in diagnostic radiography education. By analysing forms from n = 25 medical imaging providers, key fields were identified and incorporated into authentic teaching resources, intended for use
Don J. Nocum, Dania Abu Awwad, Warren Reed   +2 more
wiley   +1 more source

Thrombosis and Sickle Cell Disease

Seminars in Thrombosis and Hemostasis, 2011
Sickle cell disease (SCD) is characterized by the presence of sickle hemoglobin, which has the unique property of polymerizing when deoxygenated. The pathophysiology of acute and chronic clinical manifestations of SCD have shown the central role of dense, dehydrated red cells in acute and chronic clinical manifestations of this pathology.
DE FRANCESCHI, Lucia, Cappellini MD, OLIVIERI, Oliviero   +2 more
openaire   +2 more sources

Pre‐operative transcranial Doppler ultrasound assessment of cerebral collateral circulation in children undergoing veno‐arterial extracorporeal membrane oxygenation or cardiac surgery

Journal of Medical Radiation Sciences, EarlyView.
A pre‐cannulation survey of the circle of Willis (CoW) using transcranial Doppler (TCD) ultrasound was implemented to assess cerebral collateral circulation in children undergoing VA ECMO or cardiac surgery with cervical cannulation. The technique, in use since 2019, employs high‐end ultrasound platforms to assess brain morphology, haemorrhage and ...
Tristan Reddan, Michael Malouf, Prem Venugopal, Jennifer Powell   +3 more
wiley   +1 more source