Results 81 to 90 of about 94,881 (302)

Qualitative and Quantitative Microbiological Studies of Paediatric Artemether-Lumefantrine Dry Powders and Paracetamol Syrups Obtained from Selected Drug Stores in Accra, Ghana

Journal of Tropical Medicine, 2019
Infants and children under five years generally have high susceptibility to pathogenic and opportunistic infections due to immaturity and inexperience of their immune responses.
Solomon Opoku, Isaac Nyanor
doaj   +1 more source

Prenatal Exome Sequencing Identifies Dual Maternal‐Fetal Diagnosis of HbF Mission Bay, a Novel HBG2 Variant Associated With Methemoglobinemia, Hypoxia and Hemolytic Anemia

Prenatal Diagnosis, EarlyView.
ABSTRACT Prenatal exome sequencing (ES) can establish rare genetic diagnoses in a fetus but may also lead to occult genetic diagnosis in a biological parent. We present a case of dual fetal and maternal diagnosis by prenatal ES, in a fetus with unexplained anemia and in a pregnant patient with sickle cell disease (SCD) and recurrent unexplained hypoxia.
Matthew A. Shear, Billie Lianoglou, Ugur Hodoglugil, W. Patrick Devine, Ashutosh Lal, Juan Gonzalez, Teresa N. Sparks   +6 more
wiley   +1 more source

Automated red cell exchange in sickle cell disease patients: Retrospective analysis of series of cases in a tertiary care hospital in Eastern India

, 2022
Girijanandini Kanungo, Priyanka Nagrath, Priyanka Samal, Santosh Kumar Mishra   +3 more
openalex   +1 more source

What is the role of chest X‐ray imaging in the acute management of children with sickle cell disease? [PDF]

, 2021
Ryan Griffin, Andreas Panayiotou, Pamela B. Allen, Sue Height, Subarna Chakravorty, David C. Rees   +5 more
openalex   +1 more source

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

Prenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear, Beltran Borges, Billie R. Lianoglou, Tony Lum, Emma Canepa, Jennifer L. Cohen, Julia E. H. Brown, Akos Herzeg   +7 more
wiley   +1 more source

Findings supporting neonatal screening for sickle cell disease: an observational study in Senegal

Frontiers in Pediatrics
IntroductionSickle cell disease (SCD) is a major contributor to morbidity and mortality in sub-Saharan Africa, and early detection through neonatal screening can improve outcomes. In Senegal, systematic screening is not yet implemented.
Lucie Petigas, Ndiogou Seck, Ndiogou Seck, Dominique Doupa, Dominique Doupa, Ibrahima Diagne, Ibrahima Diagne, Matthias Roth-Kleiner, Matthias Roth-Kleiner   +8 more
doaj   +1 more source

Global, Regional, and National Epidemiology of Pediatric Stroke, 1990–2021: A Systematic Analysis From the Global Burden of Disease Study

Pediatric Discovery, EarlyView.
In 2021, the burden of pediatric stroke varied substantially across countries and regions. China and India had the highest prevalence, while India and Nigeria accounted for disproportionately high DALYs, indicating greater health loss per case. Marked geographic disparities underscore the need for region‐specific strategies.
Zhao Yang, Hanxiao Duan, Hao Chen, Hui Hu, Nandi Wang, Tiantian Luo, Jun Tang   +6 more
wiley   +1 more source

S127: CONSORTIUM ON NEWBORN SCREENING IN AFRICA FOR SICKLE CELL DISEASE

, 2022
Obiageli Nnodu, A Zapfel
openalex   +1 more source

Explosive Weapons Trauma Care Collective (EXTRACCT) Blast Injury Clinical Practice Guideline: Ocular Trauma

World Journal of Surgery, EarlyView.
This clinical practice guideline from the Explosive Weapons Trauma Care Collective (EXTRACCT) group reviews current best practice for the management of ocular trauma in conflict‐affected regions, where explosive weapons are used and healthcare infrastructure is limited.
Emma Butterfield, Alistair Bolt, Gerry Clare, John Mattia, Aung Maw Tin‐U, Iddi Ndyabawe, Larry Schwab, Siegfried Karl Wagner, On behalf of the EXTRACCT Clinical Practice Guidelines Collaboration   +8 more
wiley   +1 more source

Acute Chest Syndrome: A Rare Complication of COVID 19 in a Patient with Sickle Cell Disease

, 2022
F. Tahiri, K. Elfakiri, N. Rada, G. Draiss, M. Bouskraoui   +4 more
openalex   +1 more source