Results 121 to 130 of about 429,758 (251)

Periodontal Therapy–Related Changes in Clinical Parameters, Active‐Matrix Metalloproteinase‐8 and C‐Reactive Protein in Prediabetes and Diabetes

open access: yesOral Diseases, EarlyView.
ABSTRACT Objectives This study investigated the effect of nonsurgical periodontal therapy (NSPT) on periodontal clinical parameters, active‐matrix metalloproteinase‐8 (aMMP‐8), high sensitivity C‐reactive protein (hsCRP), and glycated hemoglobin (HbA1c), and their relationships in diabetes and prediabetes patients with periodontitis.
Kehinde Adesola Umeizudike   +8 more
wiley   +1 more source

Conditions That Limit Outpatient Abortion Care at Clinics in the United States

open access: yesPerspectives on Sexual and Reproductive Health, EarlyView.
ABSTRACT Objective While most people in the United States obtain abortion care in outpatient settings, such facilities may limit care for some individuals because of a variety of conditions. The situations when abortion care cannot be obtained in the outpatient setting have not been evaluated, leaving a deficit in understanding the need for hospital ...
Katrina Kimport   +2 more
wiley   +1 more source

The sickling pressure index predicts hemoglobin S target achievement during chronic red cell exchange in sickle cell disease

open access: yesTransfusion, EarlyView.
Abstract Background Chronic automated red cell exchange (RCE) reduces hemoglobin S (HbS) in patients with sickle cell disease (SCD), but procedural success varies across patients in ways standard exchange parameters do not explain. We introduce the Sickling Pressure Index (SPI), derived from each patient's daily rate of HbS rise (ROR) and daily rate of
Austin Choi   +3 more
wiley   +1 more source

Public perspectives on potential changes to malaria deferral criteria in Canada

open access: yesVox Sanguinis, EarlyView.
Abstract Background and Objectives As blood collection agencies (BCAs) seek to increase donor diversity, making changes to eligibility criteria to enable more people to donate is an important consideration. BCAs in Canada have a permanent deferral from whole blood and platelet donation for anyone with a history of malaria, a barrier to donation for ...
Courtney Joshua   +4 more
wiley   +1 more source

Impact of nationwide parvovirus B19 DNA screening and identification of transfusion‐transmitted infections

open access: yesVox Sanguinis, EarlyView.
Abstract Background and Objectives Parvovirus B19 (B19V) testing is often not required to release blood components. However, the European Pharmacopoeia requires that plasma pools for fractionation contain no more than 104 IU/mL of B19V DNA. In France, pool B19 nucleic acid testing (NAT) screening was performed by Établissement Français du Sang since ...
Virginie de la Taille   +12 more
wiley   +1 more source

Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI

open access: yesExperimental Physiology, EarlyView.
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley   +1 more source

Radiologic Evaluation of Paranasal Sinuses in Sickle Cell Anemia and Thalassemia: Case–Control Study

open access: yesLaryngoscope Investigative Otolaryngology
Background Sickle cell disease and thalassemia are inherited hematological disorders that are common worldwide. These patients suffer from chronic hemolytic anemia, which can result in bone marrow dysfunction and, in rare cases, extramedullary ...
Maha A. Alharbi   +8 more
doaj   +1 more source

Michael Acceptor Compounds as Hemoglobin Oxygen Affinity Modulators for Reversing Sickling of Red Blood Cells

open access: yesPharmaceuticals
Background/Objectives: Sickle cell disease (SCD) is caused by a β-globin gene mutation (βGlu6Val) that produces sickle hemoglobin (HbS). When deoxygenated, HbS polymerizes, leading to red blood cell (RBC) sickling; therefore, hemoglobin is a central ...
Khadijah A. Mohammad   +10 more
doaj   +1 more source

Metabolic stimulation improves bioenergetics and haematologic indices of circulating erythrocytes from sickle cell mice

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Metabolic stimulation improves bioenergetics, redox state, hydration and hematologic indices of circulating erythrocytes from sickle cell mice. Retained mitochondria in circulating RBCs from sickle mice are a source of RBC ATP as mitochondria function (ETC, electron transport chain) inhibitors [rotenone, a mitochondrial complex I
Luis E. F. Almeida   +4 more
wiley   +1 more source

Attitudinal and behavioral factors affecting willingness to engage in Alzheimer's disease biomarker testing

open access: yesAlzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 2, Issue 4, December 2026.
Abstract INTRODUCTION Ethnoracialized individuals, for example, Black/African American (AA), American Indian/Alaska Native (AI/AN), and Hispanic/Latinx (H/L), are underrepresented in Alzheimer's disease (AD) biomarker studies. We investigated whether and how ethnoracialized groups differ in their willingness to engage in preclinical AD biomarker ...
Diane Carol Gooding   +10 more
wiley   +1 more source

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