Results 51 to 60 of about 25,303 (208)

Evaluation of the renal function among sickle cell patients: a cross-sectional study

Italian Journal of Medicine
This cross-sectional study aimed to explore the implications and effects of hematological and kidney function patterns in individuals with sickle cell disorder (SCD) residing in the Jazan Region of Saudi Arabia.
Talal Qadah, Anwar Refaei
doaj   +1 more source

Patients with sickle cell disease taking hydroxyurea in the Hemocentro Regional de Montes Claros

Revista Brasileira de Hematologia e Hemoterapia, 2011
BACKGROUND: The development of therapies for sickle cell disease has received special attention, particularly those that reduce the polymerization of hemoglobin S.
Fernanda Kelle de Souza Santos, Caroline Nogueira Maia   +1 more
doaj   +1 more source

Sickle Cell Disease and Kidney Injury: Circulating Uromodulin Allows Early Tissue Specific Diagnosis and Monitoring of Treatment

American Journal of Hematology, EarlyView.
Ferras Alashkar, Robert Hable, Denise Zwanziger, Friederike Poppenborg, Raina Yamamoto, Hans Christian Reinhardt, Alexander Röth, Victor Herbst, Yara Bestmann, Marco Kai, Jürgen E. Scherberich   +10 more
wiley   +1 more source

SICKLE CELL DISEASE - CASE REPORTS

Journal of Nepal Medical Association, 2003
Sickle cell diseases are inherited hematological diseases, prevalent in certain parts of the world. We report two cases of sickle cell diseases, first being sickle cell b-thalassaemia and second homozygous sickle cell disease (SS).
Ram Chandra Adhikari, T B Shrestha, R B Shrestha, R C Subedi, K P Parajuli, S Dali   +5 more
doaj   +1 more source

Hydroxyurea Treatment for Sickle Cell Disease

The Scientific World Journal, 2002
High fetal hemoglobin (HbF) levels inhibit the polymerization of sickle hemoglobin (HbS) and reduce the complications of sickle cell disease. Pharmacologic agents that can reverse the switch from γ- to β-chain synthesis — γ-globin chains characterize HbF,
Martin H. Steinberg
doaj   +1 more source

Thrombocytosis and the generation of platelet‐derived microparticles in the pathophysiology of sickle cell disease

British Journal of Haematology, EarlyView.
Thrombocytosis is associated with an increased production of platelet‐derived microparticles from activated platelets, which contribute to vaso‐occlusion in sickle cell disease by perpetuating the cycle of inflammation, procoagulant state and endothelial dysfunction.
Giao N. Lê, Anna Dillon, Owen P. Smith, Corrina McMahon   +3 more
wiley   +1 more source

Hydroxyurea (hydroxycarbamide) use in adults with haemoglobin SC disease: A real‐world study in Quebec

British Journal of Haematology, EarlyView.
Summary Haemoglobin SC (HbSC) disease is the second most prevalent form of sickle cell disease, but evidence for hydroxyurea (hydroxycarbamide; HU) to prevent pain episodes was limited until the prospective identification of variables as outcomes for treatment (PIVOT) trial.
Alice Girard, Laurianne Charette, Mélissa Haouchine, Laurence Bozec, Mohamed Zakaria Bachir Bouyadjera, Mariane Poitras, Vincent‐Thierry Taillefer, Chloé Trudeau, Yves Pastore, Nathalie Letarte, Stéphanie Forté   +10 more
wiley   +1 more source

Hemoglobinas variantes em doadores de sangue do Centro de Hematologia e Hemoterapia do estado do Piauí (Hemopi): conhecendo o perfil epidemiológico para construir a rede de assistência Hemoglobin S variants in blood donors of the Hematology and Hemotherapy Center of the state of Piauí (Hemopi): understanding the epidemiological profile to create a support network

Revista Brasileira de Hematologia e Hemoterapia, 2009
The most highly prevalent inherited disease in Brazil and in the world, sickle cell anemia, is considered a public health problem. Characterized by homozygosis for the hemoglobin S gene, the individual has a range of signs and symptoms that require ...
Leonardo F. Soares, Evaldo H. Oliveira, Iraildo B. Lima, José M. Silva, Jônathas T. Mota, Claudia R. Bonini-Domingos   +5 more
doaj   +1 more source

Hemoglobin sickle cell disease in Brazil

Haematologica, 2012
We read with great interest the recent paper presented by Lionnet et al .[1][1] and we would like to briefly report our experience with hemoglobin SC (HbSC) disease. Before the institution of neonatal screening in Brazil, HbSC disease was considered a rare manifestation.[2][2] After 2001, however,
Ana Carolina Cabañas-Pedro, Josefina A. P. Braga, Roberta F Camilo-Araújo, Ana I. M. Silva, Perla Vicari, Maria Figueiredo   +5 more
openaire   +3 more sources

Evaluating high‐sensitivity troponin levels in people with sickle cell disease in the emergency department

British Journal of Haematology, EarlyView.
This study shows that sickle cell disease patients have elevated high‐sensitivity cardiac troponin I (hs‐cTnI) that is not considered clinically significant but are outside of the normal range. Elevated hs‐cTnI was associated with low haemoglobin and a history of heart failure.
Abdelrhman Mohammed, Najibah A. Galadanci, Gerhard Hellemann, Julie Kanter   +3 more
wiley   +1 more source