Results 61 to 70 of about 1,352,611 (298)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

The Effects of Lengths of Flavin Surfactant N-10-Alkyl Side Chains on Promoting Dispersion of a High-Purity and Diameter-Selective Single-Walled Nanotube

open access: yesNanomaterials, 2022
Flavin with defined helical self-assembly helps to understand chemical designs for obtaining high-purity semiconducting (s)-single-walled carbon nanotubes (SWNT) in a diameter (dt)-selective manner for high-end applications.
Minsuk Park   +2 more
doaj   +1 more source

Finite size effects on calorimetric cooperativity of two-state proteins

open access: yes, 2004
Finite size effects on the calorimetric cooperatity of the folding-unfolding transition in two-state proteins are considered using the Go lattice models with and without side chains.
Betancourt   +22 more
core   +1 more source

Network structure of polyfluorene sheets as a function of alkyl side chain length [PDF]

open access: yesPhysical Review E, 2011
The formation of self-organized structures in poly(9,9-di-n-alkylfluorene)s ∼1 vol % methylcyclohexane (MCH) and deuterated MCH (MCH-d(14)) solutions was studied at room temperature using neutron and x-ray scattering (with the overall q range of 0.00058-4.29 Å(-1)) and optical spectroscopy. The number of side chain carbons (N) ranged from 6 to 10.
Knaapila, M.   +10 more
openaire   +3 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Thermal Degradation of Adsorbed Bottle-Brush Macromolecules: Molecular Dynamics Simulation

open access: yes, 2011
The scission kinetics of bottle-brush molecules in solution and on an adhesive substrate is modeled by means of Molecular Dynamics simulation with Langevin thermostat.
Allen N. S.   +30 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Conformational Studies of ε- CBz- L- Lysine and L- Valine Block Copolypeptides

open access: yesE-Journal of Chemistry, 2010
Conformational studies of ε-CBz-L-lysine and L-valine block copoylpeptides using x- ray diffraction and CD spectra are described. The block copolypeptides contain valine block in the center and on both side of the valine are ε-CBz-L-lysine blocks.
Ajay Kumar
doaj   +1 more source

Finite-Length Analyses for Source and Channel Coding on Markov Chains

open access: yesEntropy, 2020
We derive finite-length bounds for two problems with Markov chains: source coding with side-information where the source and side-information are a joint Markov chain and channel coding for channels with Markovian conditional additive noise.
Masahito Hayashi, Shun Watanabe
doaj   +1 more source

Effects of disorder on two strongly correlated coupled chains

open access: yes, 1997
We study the effects of disorder on a system of two coupled chain of strongly correlated fermions (ladder system), using renormalization group. The stability of the phases of the pure system is investigated as a function of interactions both for fermions
A. A. Abrikosov   +85 more
core   +2 more sources

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