Results 121 to 130 of about 15,861 (227)
Expression pattern of Siglec-F.
, 2014 Immunohistochemistry and immunofluorescence Siglec-F staining of lung sections and BAL cytospins of mice with EAAD (A - D, upper panels) and controls (A – D, lower panels).
Frauke Alves (77578) +5 more
core +1 more source
Targeting Siglec-7 and Siglec-9 with Sialic Acid Coated Nanoparticles
, 2014 Systemic Lupus Erythematosus (SLE) is an autoimmune disease which is well characterized by the over production of proinflammatory cytokines such as type I interferons (IFN) and TNFα, downstream of the pathogen recognition toll-like receptors, TLR-7 and ...
Barbara M. Coffey (7962080)
core +1 more source
Study of Human-Specific Microglial Receptor Siglec-11 and Generation of Transgenic Mice Expressing Human Siglec-11 [PDF]
, 2009 Siglec-11 is a recently identified human-specific CD33-related Siglec expressed on microglia. The full-length cDNA of Siglec-11 encodes 5 extracellular Ig-like domains, a single pass transmembrane domain, and a cytosolic tail, which contains ITIMs.
Wang, Yiner
core +1 more source
Siglec-7 localization in human platelets.
, 2014 (A) Siglec-7 does not colocalize with markers for dense granules, lysosomes, T-granules or endosomes. From top to bottom: intra-platelet Siglec-7 was co-stained with serotonin (dense granules), M6P (endosomes), TLR-9 (T-granules), and LAMP-1 (lysosomes ...
Hind Hamzeh-Cognasse (78447) +8 more
core +1 more source
The expression characteristic and prognostic role of Siglec‐15 in lung adenocarcinoma
The Clinical Respiratory JournalSialic acid‐binding immunoglobulin‐like lectin‐15 (Siglec‐15) has been identified as an immune suppressor and a promising candidate for immunotherapy of cancer management.
Haijun Sun +7 more
doaj +1 more source
Expression of Siglec-7 in human platelets.
, 2014 (A), (B) Siglec-7 expression in platelets was analyzed by flow cytometry (n = 20). Platelets (stimulated with TRAP or vehicle control) were labeled with anti-CD41a and anti-Siglec-7 mAbs.
Hind Hamzeh-Cognasse (78447) +8 more
core +1 more source
The Journal of Clinical InvestigationProstate cancer is the second leading cause of male cancer death in the U.S. Current immune checkpoint inhibitor–based immunotherapies have improved survival for many malignancies; however, they have failed to prolong survival for prostate cancer ...
Ru M. Wen +16 more
doaj +1 more source
, 1999 We describe the characterization of sialic acid-binding Ig-like lectin-7 (siglec-7), a novel member of the siglec subgroup of the immunoglobulin superfamily.
Ni, J +16 more
core +1 more source
Interaction of Siglec-4 with naturally occurring and synthetic glycoconjugates
, 2011 The aim of this work has been to provide insights into the structure-function relationship of Siglec-4 binding naturally occurring sialic acids as well as synthetic sialic acid derivatives.
Koliwer-Brandl, Hendrik
core
Siglec-6 as a therapeutic target for cell migration and adhesion in chronic lymphocytic leukemia
Nature CommunicationsSiglec-6 is a lectin receptor with restricted expression in the placenta, mast cells and memory B-cells. Although Siglec-6 is expressed in patients with chronic lymphocytic leukemia (CLL), its pathophysiological role has not been elucidated.
Jessica Nunes +9 more
doaj +1 more source