Results 51 to 60 of about 5,116,497 (296)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Magnetism of Sigma-Phase Fe68V32 Compound

open access: yes, 2020
The magnetic phase diagram in the H-T coordinates has been determined for σ-Fe68V32 from the ZFC/FC magnetization measurements. The re-entrant character of magnetism, going from paramagnetic through ferromagnetic to spin-glass (SG) states, has been evidenced. The SG phase is magnetically heterogeneous, because two sub phases can be identified i.e. with
Konieczny, Piotr, Dubiel, Stanisław M.
openaire   +2 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Effects of cold rolling on phase precipitation and phase transformation in a 2507 SDSS [PDF]

open access: yes, 2011
In the present work 7 samples of UNS S32750 was cold rolled at different rates, analyzed in this state and also after the ageing for 2400s at 400 and 900°C.\nInvestigation was carry out with: OM SEM ( EBSD EDS) Magnetic tests: Forster, Permeameter ...
Bianchi, Marco
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Effect of Sigma Phase Precipitation on the Pitting Corrosion Mechanism of Duplex Stainless Steels

open access: yesInternational Journal of Electrochemical Science, 2018
A new phenomenon of the pitting corrosion of three duplex stainless steels (DSSs), SAF2205, SAF2507 and Z3CN20.09M, induced by sigma phases is found and discussed. The pitting potential (Ep) of all three DSS specimens with smaller variations in the level
Wang Yongqiang   +4 more
doaj   +1 more source

Effect of niobium in the phase transformation and corrosion resistance of one austenitic-ferritic stainless steel [PDF]

open access: yesMaterials Research, 2014
Austenitic-ferritic stainless steels containing 0.2% and 0.5% niobium were evaluated with respect to the microstructures, microhardness, pitting potential resistance, electrochemical impedance and wearing tests. Niobium is an alphagenic element and has a
André Itman Filho   +3 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Global Health Policy Position Statement [PDF]

open access: yes, 2018
Issue being addressed: Clarification of Sigma Theta Tau International Honor Society\u27s desired role in health ...
Sigma Theta Tau International
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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