Results 71 to 80 of about 904,230 (261)
Low-Temperature Mechanical Behavior of Super Duplex Stainless Steel with Sigma Precipitation
Metals, 2015 Experimental studies in various aspects have to be conducted to maintain stable applications of super duplex stainless steels (SDSS) because the occurrence rate of sigma phase, variable temperature and growth direction of sigma phase can influence ...
Seul-Kee Kim +3 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Corrosion and Materials DegradationWe studied the effect of isothermal annealing (600–750 °C, 1 to 1000 min) on the microstructure and mechanical properties of SAF 2205 duplex stainless steel.
Jaka Burja +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
A minimalistic pure spinor sigma-model in AdS
Journal of High Energy Physics, 2018 The b-ghost of the pure spinor formalism in a general curved background is not holomorphic. For such theories, the construction of the string measure requires the knowledge of the action of diffeomorphisms on the BV phase space.
Andrei Mikhailov
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Investigating the sigma formation in homogenization treatment of the 309L stainless cast billet
Journal of Materials Research and Technology309L is a low-carbon (0.03 wt% max) and high-alloy austenitic stainless steel, which is particularly valued for the welding filler wire application. The 309L cast billet is commonly used to produce ultra-fine welding filler wire.
Hung-Yang Chu +3 more
doaj +1 more source
Six Sigma as a method of improving the quality of service process
Production Engineering Archives, 2018 The objective of the analysis conducted and described in this paper has been to present the practical application of the Six Sigma method based on the DMAIC cycle in improving the quality of the service process. The first part of the article contains the
Kowalik Kamila
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source