Results 61 to 70 of about 5,116,497 (296)

Sigma receptor ligands: novel applications in cancer imaging and treatment [PDF]

open access: yes, 2012
Sigma receptoren (subtypes sigma-1 en sigma-2) zijn unieke bindingsplaatsen die een aanzienlijk hogere expressie vertonen in kanker dan in gezond weefsel.
Rybczynska, Anna A.,   +1 more
core   +1 more source

Effect of Zn addition on the microstructures and mechanical behaviors of As-cast Mg-2.5Y-1Ce-0.5Mn alloy

open access: yesMaterials Research Express, 2020
The effect of Zn addition on the microstructures and mechanical behaviors of as-cast Mg-2.5Y-1Ce-0.5Mn alloy was investigated. Microstructure observation demonstrated that with the addition of 1wt%, 3wt% and 5wt% Zn, the ternary phases of LPSO phase ...
Xiaoru Zhang   +8 more
doaj   +1 more source

Kinetics of the Chiral Phase Transition in a Quark–Meson \(\sigma \) Model

open access: yesActa Physica Polonica B Proceedings Supplement, 2023
Acta physica Polonica / B 16(1), 1 - A89 (2023).
van Hees, H.   +2 more
openaire   +4 more sources

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Design methodology for a maximum sequence length MASH digital delta-sigma modulator [PDF]

open access: yes, 2009
The paper proposes a novel structure for a MASH digital delta-sigma modulator (DDSM) in order to achieve a long sequence length. The expression for the sequence length is derived. The condition to produce the maximum sequence length is also stated. It is
Xu, Tao, Condon, Marissa
core   +2 more sources

Regulation of Proteolysis of the Stationary-Phase Sigma Factor RpoS [PDF]

open access: yesJournal of Bacteriology, 1998
ABSTRACT RpoS, the stationary-phase sigma factor of Escherichia coli , is responsible for increased transcription of an array of genes when cells enter stationary phase and under certain stress conditions.
Y, Zhou, S, Gottesman
openaire   +2 more sources

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

On the Debye temperature in sigma-phase Fe–V alloys [PDF]

open access: yesIntermetallics, 2010
A series of sigma-phase Fe_{100-x}V_x samples with 34.4 < x < 59.0 were investigated by neutron and X-ray diffraction and Mossbauer spectroscopy (MS) techniques. The first two methods were used for verification of the transformation from alpha to sigma phase and they also permitted to determine lattice parameters of the unit cell.
Cieslak, Jakub   +4 more
openaire   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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