Results 31 to 40 of about 452,071 (254)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Comparative Analysis of Mycoplasma gallisepticum vlhA Promoters
Frontiers in Genetics, 2018 Mycoplasma gallisepticum is an intracellular parasite affecting respiratory tract of poultry that belongs to class Mollicutes. M. gallisepticum features numerous variable lipoprotein hemagglutinin genes (vlhA) that play a role in immune escape.
Mikhail Orlov +3 more
doaj +1 more source
Characteristics of CALIOP attenuated backscatter noise: implication for cloud/aerosol detection [PDF]
Atmospheric Chemistry and Physics, 2011 A research algorithm is developed for noise evaluation and feature detection of the CALIOP (Cloud-Aerosol Lidar with Orthogonal Polarization) Level 1 (L1) backscatter data with an emphasis on cloud/aerosol features in the upper troposphere and lower ...
D. L. Wu +3 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Role of two RpoN in Bradyrhizobium sp. strain DOA9 in symbiosis and free-living growth
Frontiers in Microbiology, 2023 RpoN is an alternative sigma factor (sigma 54) that recruits the core RNA polymerase to promoters of genes. In bacteria, RpoN has diverse physiological functions.
Jenjira Wongdee +8 more
doaj +1 more source
Pharmacological profiling of sigma 1 receptor ligands by novel receptor homomer assays
Neuropharmacology, 2018 The sigma 1 receptor (σ1R) is a structurally unique transmembrane protein that functions as a molecular chaperone in the endoplasmic reticulum (ER), and has been implicated in cancer, neuropathic pain, and psychostimulant abuse. Despite physiological and pharmacological significance, mechanistic underpinnings of structure-function relationships of σ1R ...
Hideaki Yano +9 more
openaire +3 more sources
RSC Advances, 2022 Selective action of γ-butyrolactones and oxazolidinones towards σ2 receptor.
Richie R. Bhandare +4 more
openaire +2 more sources
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The lipid-modulating effect of berberine in hyperlipidemic ApoE−/− mice
Frontiers in PharmacologyIntroductionBerberine, a natural alkaloid from plants of the genus Coptis, shows significant lipid-lowering effects clinically. However, its exact mechanism in lipid metabolism is not fully understood.
Naixin Shi +3 more
doaj +1 more source
SSCG with Hershey-Kiss modulation profile using Dual Sigma-Delta modulators
IEICE Electronics Express, 2010 This letter describes a spread spectrum clock generator (SSCG) circuit with the Hershey-Kiss modulation profile using two stacked sigma-delta modulators. The proposed Hershey-Kiss profile modulator generates various slopes to achieve non-linear modulation profile.
Park, Hyung-Min +2 more
openaire +2 more sources