Results 41 to 50 of about 1,912,516 (286)
Characteristics of CALIOP attenuated backscatter noise: implication for cloud/aerosol detection [PDF]
Atmospheric Chemistry and Physics, 2011 A research algorithm is developed for noise evaluation and feature detection of the CALIOP (Cloud-Aerosol Lidar with Orthogonal Polarization) Level 1 (L1) backscatter data with an emphasis on cloud/aerosol features in the upper troposphere and lower ...
D. L. Wu +3 more
doaj +1 more source
Pharmacological profiling of sigma 1 receptor ligands by novel receptor homomer assays
Neuropharmacology, 2018 The sigma 1 receptor (σ1R) is a structurally unique transmembrane protein that functions as a molecular chaperone in the endoplasmic reticulum (ER), and has been implicated in cancer, neuropathic pain, and psychostimulant abuse. Despite physiological and pharmacological significance, mechanistic underpinnings of structure-function relationships of σ1R ...
Hideaki Yano +9 more
openaire +3 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Global Health Policy Position Statement [PDF]
, 2018 Issue being addressed: Clarification of Sigma Theta Tau International Honor Society\u27s desired role in health ...
Sigma Theta Tau International
core
Lean six sigma in a call centre : a case study [PDF]
, 2010 This paper, a case study, aims to illustrate the application of lean six sigma in a call centre of a service industry corporation. The study draws on process information and primary data from a real project.
Antony, Jiju +2 more
core +3 more sources
Role of two RpoN in Bradyrhizobium sp. strain DOA9 in symbiosis and free-living growth
Frontiers in Microbiology, 2023 RpoN is an alternative sigma factor (sigma 54) that recruits the core RNA polymerase to promoters of genes. In bacteria, RpoN has diverse physiological functions.
Jenjira Wongdee +8 more
doaj +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
The lipid-modulating effect of berberine in hyperlipidemic ApoE−/− mice
Frontiers in PharmacologyIntroductionBerberine, a natural alkaloid from plants of the genus Coptis, shows significant lipid-lowering effects clinically. However, its exact mechanism in lipid metabolism is not fully understood.
Naixin Shi +3 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
25th International Nursing Research Congress 2014 Conference Proceedings and Enhanced Abstracts of Oral and Poster Presentations [PDF]
, 2015 Sigma Theta Tau International the Honor Society of Nursing (Sigma) conducted its 25th International Nursing Research Congress at the Hong Kong Convention and Exhibition Centre, 24-28 July 2014.
Sigma Theta Tau International
core