Results 61 to 70 of about 813,237 (289)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Investigations of Effects of Surface Temperature and Single Roughness Elements on Boundary-Layer Transition [PDF]
, 1947 The laminar boundary layer and the position of the transition point are investigated on a heated flat plate. It was found that the Reynolds number of transition decreases as the temperature of the plate is increased.
Fila, Gertrude H., Liepmann, Hans W.
core +1 more source
, 2011 We have obtained 18 new high-resolution spectropolarimetric observations of the B2Vp star sigma Ori E with both the Narval and ESPaDOnS spectropolarimeters.
Bohlender +48 more
core +3 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Listeria monocytogenes σA Is Sufficient to Survive Gallbladder Bile Exposure
Frontiers in Microbiology, 2019 Listeria monocytogenes is a foodborne Gram-positive bacterium causing listeriosis in both animals and humans. It can persist and grow in various environments including conditions countered during saprophytic or intra-host lifestyles. Sigma (σ) subunit of
Atsadang Boonmee +2 more
doaj +1 more source
Ground-based stratospheric O3 and HNO3 measurements at Thule, Greenland: an intercomparison with Aura MLS observations [PDF]
Atmospheric Measurement Techniques, 2013 In response to the need for improving our understanding of the evolution and the interannual variability of the winter Arctic stratosphere, in January 2009 a Ground-Based Millimeter-wave Spectrometer (GBMS) was installed at the Network for the Detection ...
I. Fiorucci +3 more
doaj +1 more source
Statistical Process Control for Monitoring Nonlinear Profiles: A Six Sigma Project on Curing Process [PDF]
Quality Engineering, 2012 This article describes a successful Six Sigma project in the context of statistical engineering for integrating SPC, a statistical method, to the existing practice of engineering process control (EPC) according to science.
Chang, Shing I. +4 more
openaire +2 more sources
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
International Journal of HyperthermiaIntroduction Hyperthermia efficacy depends on the temperatures achieved in the target area. Therefore, hyperthermia systems must deliver both controlled and conformal heating. This study presents a comprehensive multi-institutional quality assurance (QA)
Mattia De Lazzari +5 more
doaj +1 more source
Solar Neutron Events of October-November 2003
, 2005 During the period when the Sun was intensely active on October-November 2003, two remarkable solar neutron events were observed by the ground-based neutron monitors.
A. Hurtado +20 more
core +1 more source