Results 81 to 90 of about 813,237 (289)
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
, 2006 We analyze photometric properties of 1384 cluster galaxies as a function of the normalized distance to cluster center. These galaxies were selected in the central region ($r/r_{200} \leq$ 0.8) of 14 southern Abell clusters chosen from the Southern Abell ...
Carlos José Donzelli +7 more
core +1 more source
Coking-Resistant Sub-Nano Dehydrogenation Catalysts: PtnSnx/SiO2 (n=4, 7) [PDF]
, 2020 We present a combined experimental/theoretical study of Pt$_n$/SiO$_2$ and Pt$_n$Sn$_x$/SiO$_2$ (n = 4, 7) model catalysts for the endothermic dehydrogenation of hydrocarbons, using the ethylene intermediate as a model reactant.
Alexandrova, Anastassia N +5 more
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Understanding the Unique Assembly History of Central Group Galaxies
, 2014 Central Galaxies (CGs) in massive halos live in unique environments with formation histories closely linked to that of the host halo. In local clusters they have larger sizes ($R_e$) and lower velocity dispersions (sigma) at fixed stellar mass M_star ...
Auger, Matthew +9 more
core +3 more sources
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Investigation of Effects of Surface Temperature and Single Roughness Elements on Boundary-Layer Transition [PDF]
, 1947 The laminar boundaxy layer and the position of the transition point were investigated on a heated flat plate. It was found that the Reynolds number of transition decreases as the temperature of the plate is increased.
Fila, Gertrude H., Liepmann, Hans W.
core +1 more source
The outer regions of galaxy clusters: Chandra constraints on the X-ray surface brightness
, 2009 (Abridged version) We study the properties of the X-ray surface brightness profiles in a sample of galaxy clusters that were observed with Chandra and have emission detectable with a signal-to-noise ratio higher than 2 at a radius beyond R500 ~ 0.7 R200.
Allen +24 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source