Results 51 to 60 of about 813,237 (289)

The lipid-modulating effect of berberine in hyperlipidemic ApoE−/− mice

open access: yesFrontiers in Pharmacology
IntroductionBerberine, a natural alkaloid from plants of the genus Coptis, shows significant lipid-lowering effects clinically. However, its exact mechanism in lipid metabolism is not fully understood.
Naixin Shi   +3 more
doaj   +1 more source

Homogenizing and estimating the uncertainty in NOAA's long-term vertical ozone profile records measured with the electrochemical concentration cell ozonesonde [PDF]

open access: yesAtmospheric Measurement Techniques, 2018
NOAA's program of long-term monitoring of the vertical distribution of ozone with electrochemical concentration cell (ECC) ozonesondes has undergone a number of changes over the 50-year record.
C. W. Sterling   +13 more
doaj   +1 more source

Statistics of level spacing of geometric resonances in random binary composites

open access: yes, 2001
We study the statistics of level spacing of geometric resonances in the disordered binary networks. For a definite concentration $p$ within the interval $[0.2,0.7]$, numerical calculations indicate that the unfolded level spacing distribution $P(t)$ and ...
B.I. Shklovskii   +19 more
core   +1 more source

SSCG with Hershey-Kiss modulation profile using Dual Sigma-Delta modulators

open access: yesIEICE Electronics Express, 2010
This letter describes a spread spectrum clock generator (SSCG) circuit with the Hershey-Kiss modulation profile using two stacked sigma-delta modulators. The proposed Hershey-Kiss profile modulator generates various slopes to achieve non-linear modulation profile.
Hyung-Min Park   +2 more
openaire   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Exploring the role of sigma factor gene expression on production by Corynebacterium glutamicum: sigma factor H and FMN as example

open access: yesFrontiers in Microbiology, 2015
Bacteria are known to cope with environmental changes by using alternative sigma factors binding to RNA polymerase core enzyme. Sigma factor is one of the targets to modify transcription regulation in bacteria and to influence production capacities.
Hironori eTaniguchi, Volker F. Wendisch
doaj   +1 more source

Structural properties of prokaryotic promoter regions correlate with functional features. [PDF]

open access: yesPLoS ONE, 2014
The structural properties of the DNA molecule are known to play a critical role in transcription. In this paper, the structural profiles of promoter regions were studied within the context of their diversity and their function for eleven prokaryotic ...
Pieter Meysman   +5 more
doaj   +1 more source

The MASSIVE Survey - VIII. Stellar Velocity Dispersion Profiles and Environmental Dependence of Early-Type Galaxies

open access: yes, 2017
We measure the radial profiles of the stellar velocity dispersions, $\sigma(R)$, for 90 early-type galaxies (ETGs) in the MASSIVE survey, a volume-limited integral-field spectroscopic (IFS) galaxy survey targeting all northern-sky ETGs with absolute $K ...
Blakeslee, John P.   +6 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Feeding and Feedback in the Inner Kiloparsec of the Active Galaxy NGC2110 [PDF]

open access: yes, 2013
We present two-dimensional gaseous kinematics of the inner 1.1 x 1.6kpc^2 of the Seyfert 2 galaxy NGC2110, from optical spectra obtained with the GMOS integral field spectrograph on the Gemini South telescope at a spatial resolution of 100pc.
Couto, Guilherme S.   +6 more
core   +2 more sources

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