Results 251 to 260 of about 6,973,238 (322)
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Angewandte Chemie - International Edition, 2022
MicroRNA (miRNA) imaging in disease sites is vital to elucidate their role in cancer progression. However, limited tumor specificity remains a major barrier for traditional amplification approaches due to associated background signal leakage.
Qing Liu +5 more
semanticscholar +3 more sources
MicroRNA (miRNA) imaging in disease sites is vital to elucidate their role in cancer progression. However, limited tumor specificity remains a major barrier for traditional amplification approaches due to associated background signal leakage.
Qing Liu +5 more
semanticscholar +3 more sources
Sensing through signal amplification
Chemical Society Reviews, 2011The naked eye detection of single molecules in a complex mixture is the ultimate detection limit. Since a single molecule is unable to generate a strong enough signal, sensing methodologies able to reach that limit by necessity need to rely on signal amplification. This tutorial review describes various molecular approaches towards signal amplification
Scrimin, P.; Prins, L.J.
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Coordination Chemistry Reviews, 2020
Electrochemical sensor is a promising detection device with the characteristics of simplicity, rapidity, portability, and high sensitivity. With the increasing demands for ultrasensitive detection, extensive signal amplification strategies have been ...
Shiyu Liu +12 more
semanticscholar +3 more sources
Electrochemical sensor is a promising detection device with the characteristics of simplicity, rapidity, portability, and high sensitivity. With the increasing demands for ultrasensitive detection, extensive signal amplification strategies have been ...
Shiyu Liu +12 more
semanticscholar +3 more sources
Signal Amplification by Allosteric Catalysis
Angewandte Chemie International Edition, 2006AbstractIn this article we unify a series of recent studies on bio‐ and chemosensors under a single signaling strategy: signal amplification by allosteric catalysis (SAAC). The SAAC strategy mimics biological signal transduction processes, where molecular recognition between an external signal and a protein receptor is allosterically transduced into ...
Lei, Zhu, Eric V, Anslyn
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Recent advances on signal amplification strategies in photoelectrochemical sensing of microRNAs.
Biosensors and Bioelectronics, 2020As an important non-coding, evolutionary conserved, and post-transcriptional gene regulators of genome, microRNAs (miRNAs) have received extensive attention from various disciplines in the important role of biological processes and the connection with ...
Fei Li, Yunlei Zhou, Huanshun Yin, S. Ai
semanticscholar +3 more sources
Angewandte Chemie - International Edition, 2019
The precise control over signal amplification provides unparalleled opportunities for diverse applications. However, the creation of spatiotemporally controlled amplification has not been realized because of the lack of a design methodology.
Hongqian Chu +4 more
semanticscholar +3 more sources
The precise control over signal amplification provides unparalleled opportunities for diverse applications. However, the creation of spatiotemporally controlled amplification has not been realized because of the lack of a design methodology.
Hongqian Chu +4 more
semanticscholar +3 more sources
Signal amplification strategies in electrochemiluminescence biosensors
Chemical Engineering Journal, 2023Dong Han, Kui Yang, Shiguo Sun, J. Wen
semanticscholar +3 more sources
Bipolar electrochemiluminescence sensors: From signal amplification strategies to sensing formats
Coordination Chemistry Reviews, 2021Zhi-Yuan Che +3 more
semanticscholar +3 more sources
Biosensors & bioelectronics, 2023
In this work, PtPd nanoparticles functionalized porphyrin metal-organic framework nanoenzymes (PtPd@PCN-224 nanoenzymes) are exploited as signal amplification tags to fabricate a rapid and ultrasensitive sensitive CRISPR/Cas14a-based electrochemical ...
Cai-xia Li +10 more
semanticscholar +1 more source
In this work, PtPd nanoparticles functionalized porphyrin metal-organic framework nanoenzymes (PtPd@PCN-224 nanoenzymes) are exploited as signal amplification tags to fabricate a rapid and ultrasensitive sensitive CRISPR/Cas14a-based electrochemical ...
Cai-xia Li +10 more
semanticscholar +1 more source
Biosensors & bioelectronics, 2023
In addition to carrying and transmitting genetic material, some DNA molecules have specific binding ability or catalytic function. DNA with this special function is collectively referred to as functional DNA (fDNA), such as aptamer, DNAzyme and so on ...
Yuanyuan Zhu, Jian Wu, Qingli Zhou
semanticscholar +1 more source
In addition to carrying and transmitting genetic material, some DNA molecules have specific binding ability or catalytic function. DNA with this special function is collectively referred to as functional DNA (fDNA), such as aptamer, DNAzyme and so on ...
Yuanyuan Zhu, Jian Wu, Qingli Zhou
semanticscholar +1 more source