Results 251 to 260 of about 517,159 (303)

Advances in Research on Isothermal Signal Amplification Mediated MicroRNA Detection of Clinical Samples: Application to Disease Diagnosis. [PDF]

Biosensors (Basel)
Han Y, Sun X, Cai S.
europepmc   +1 more source

Isothermal signal amplification-mediated nanozyme capture on DNA tetrahedra for ultrasensitive amperometric immunoassay of Epstein-Barr virus latent membrane protein 1. [PDF]

Front Chem
Liao L, Li Z, Liu Z, Qiu B, Guo W.
europepmc   +1 more source

¹⁵N NMR Signal Amplification by Reversible Exchange of [¹⁵N₃]Ornidazole Antibiotic. [PDF]

J Phys Chem B
Yi AP, Chukanov NV, Kabir MSH, Trepakova AI, Chekmenev EY, Salnikov OG, Koptyug IV.   +6 more
europepmc   +1 more source

Sensing through signal amplification

Chemical Society Reviews, 2011
The naked eye detection of single molecules in a complex mixture is the ultimate detection limit. Since a single molecule is unable to generate a strong enough signal, sensing methodologies able to reach that limit by necessity need to rely on signal amplification. This tutorial review describes various molecular approaches towards signal amplification
Scrimin, P.; Prins, L.J.
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Signal Amplification by Allosteric Catalysis

Angewandte Chemie - International Edition, 2006
AbstractIn this article we unify a series of recent studies on bio‐ and chemosensors under a single signaling strategy: signal amplification by allosteric catalysis (SAAC). The SAAC strategy mimics biological signal transduction processes, where molecular recognition between an external signal and a protein receptor is allosterically transduced into ...
Lei Zhu, Eric V Anslyn
exaly   +3 more sources

Antigen Retrieval and Signal Amplification

, 2021
Immunohistochemistry (IHC) offers a valuable method for determining the spatial distribution of proteins in cells and tissues. Fixation of tissues prior IHC enables their long-term stability and preserves tissue morphology; however, downstream analysis of protein localization within fixed samples can be complicated by cross-links formed between ...
Logan, Dunkenberger, Luis, Del Valle
openaire   +3 more sources

Signal Amplification

Science's STKE, 2000
CD19 is a transmembrane protein that is part of a complex that controls signaling through the B cell receptor (BCR). Knockout of CD19 results in impaired B cell signaling, and overexpression of CD19 enhances B cell signaling. Fujimoto et al .
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Signaling Amplification at the Immunological Synapse

2009
The immunological synapse is a dynamic structure, formed between a T cell and one or more antigen-presenting cells, characterized by lipid and protein segregation, signaling compartmentalization, and bidirectional information exchange through soluble and membrane-bound transmitters.
VIOLA, ANTONELLA, CONTENTO, RITA LUCIA, MOLON, BARBARA   +2 more
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Aptamer amplification: divide and signal

Expert Opinion on Medical Diagnostics, 2008
Aptamers are selected nucleic acids that bind their targets with affinities and specificities that are often comparable to those of monoclonal antibodies.Although aptamers have been adapted to a wide variety of assay formats, the fact that they are nucleic acids makes them uniquely useful for adaptation to amplification assays.
Supriya, Pai, Ana, Roberts, Andrew D, Ellington   +2 more
openaire   +2 more sources

Noiseless Independent Signal and Power Amplification

Technical Digest. 1998 EQEC. European Quantum Electronics Conference (Cat. No.98TH8326), 1998
We present a noiseless optical amplifier comprising a signal-amplifying feed-forward loop and a power-amplifying injection-locked laser. We demonstrate that the signal amplifier can attain a signal-transfer coefficient limited solely by the quantum efficiency of our in-loop photodetector and that we can independently amplify the optical power while ...
Huntington, EH, Lam, PK, Ralph, TC, McClelland, DE, Bachor, HA   +4 more
openaire   +4 more sources