Results 261 to 270 of about 6,973,238 (322)

A microfluidic chemiluminescence biosensor based on multiple signal amplification for rapid and sensitive detection of E.coli O157:H7.

Biosensors & bioelectronics, 2022
E. coli O157:H7 has become a crucial foodborne pathogen with certain morbidity and mortality. However, the available methods still face the significant challenges including the improvement of detection specificity and sensitivity for real sample analysis.
Dong-Xia Sun, Tingting Fan, Feng Liu, Fangxiu Wang, Dan Gao, Jin-Ming Lin   +5 more
semanticscholar   +1 more source

Photoacoustic Imaging and Photothermal Therapy of Semiconducting Polymer Nanoparticles: Signal Amplification and Second Near-Infrared Construction.

Small, 2021
Photoacoustic (PA) imaging and photothermal therapy (PTT) have attracted extensive attention in disease diagnosis and treatment. Although many exogenous contrast agents have been developed for PA imaging and PTT, the design guidelines to amplify their ...
Xu Zhen, Kanyi Pu, Xiqun Jiang
semanticscholar   +1 more source

Signal amplification and output of CRISPR/Cas-based biosensing systems: A review.

Analytica Chimica Acta, 2021
CRISPR (clustered regularly interspaced short palindromic repeats)/Cas (CRISPR-associated) proteins are powerful gene-editing tools because of their ability to accurately recognize and manipulate nucleic acids.
Si-yuan Wang, Yichen Du, Dong-Xia Wang, Jianzhong Ma, An-Na Tang, Deming Kong   +5 more
semanticscholar   +1 more source

Electrochemical Immunosensor for Cardiac Troponin I Detection Based on Covalent Organic Framework and Enzyme-Catalyzed Signal Amplification.

Analytical Chemistry, 2021
Herein, a highly sensitive electrochemical immunosensor was presented for the cardiac troponin I (cTnI) determination using a multifunctional covalent organic framework-based nanocomposite (HRP-Ab2-Au-COF) as the signal amplification probe. The spherical
Sinuo Feng, Mengxia Yan, Yu Xue, Jianshe Huang, Xiurong Yang   +4 more
semanticscholar   +1 more source

Current signal amplification strategies in aptamer-based electrochemical biosensor: A review

, 2021
Due to their high specificity and affinity towards various targets, along with other unique advantages such as stability and low cost, aptamers are widely applied in analytical techniques.
Lei He, Rongrong Huang, Pengfeng Xiao, Yuan Liu, Lian Jin, Hongna Liu, Song Li, Yan Deng, Zhu Chen, Zhiyang Li, N. He   +10 more
semanticscholar   +1 more source

Nanomaterials as signal amplification elements in aptamer-based electrochemiluminescent biosensors.

Bioelectrochemistry, 2022
Biosensor technology is experiencing an unprecedented momentum that is driven by rapid advances in material science for utilization in various fields, and is constantly evolving to develop fast, simple and sensitive sensors.
Chitra Padmakumari Kurup, Syazana Abdullah Lim, M. Ahmed   +2 more
semanticscholar   +1 more source

Signal Amplification

Science's STKE, 2000
CD19 is a transmembrane protein that is part of a complex that controls signaling through the B cell receptor (BCR). Knockout of CD19 results in impaired B cell signaling, and overexpression of CD19 enhances B cell signaling. Fujimoto et al .
  +4 more sources

Optically Programmable Plasmon Enhanced Fluorescence-Catalytic Hairpin Assembly Signal Amplification Strategy for Spatiotemporally Precise Imaging.

Analytical Chemistry, 2022
Signal amplification strategies with spatiotemporally high sensitivity can provide more accurate information and hold great promise for improving the accuracy of disease diagnosis.
Tingting Zhao, Xiaomei Sun, J. Chen, Dan Li, W. Cao, Shuwei Chen, Yue Yin, Shenghao Xu, Xiliang Luo   +8 more
semanticscholar   +1 more source

Recent advances in DNA walker machines and their applications coupled with signal amplification strategies: A critical review.

Analytica Chimica Acta, 2021
DNA walkers, a type of dynamic nanomachines, have become the subject of burgeoning research in the field of biology. These walkers are powered by driving forces based on strand displacement reactions, protein enzyme/DNAzyme reactions and conformational ...
Mingdi Xu, D. Tang
semanticscholar   +1 more source

Antigen Retrieval and Signal Amplification

2021
Immunohistochemistry (IHC) offers a valuable method for determining the spatial distribution of proteins in cells and tissues. Fixation of tissues prior IHC enables their long-term stability and preserves tissue morphology; however, downstream analysis of protein localization within fixed samples can be complicated by cross-links formed between ...
Logan, Dunkenberger, Luis, Del Valle
openaire   +2 more sources