Results 121 to 130 of about 1,664,025 (288)

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Takens-Based Kernel Transfer Entropy Connectivity Network for Motor Imagery Classification

Sensors
Reliable decoding of motor imagery (MI) from electroencephalographic signals remains a challenging problem due to their nonlinear, noisy, and non-stationary nature. To address this issue, this work proposes an end-to-end deep learning model, termed TEKTE-
Alejandra Gomez-Rivera, Andrés M. Álvarez-Meza, David Cárdenas-Peña, Alvaro Orozco-Gutierrez   +3 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Optimization of Interconnected Natural Gas and Power Systems Using Mathematical Programs with Complementarity Constraints

Mathematics
The demand for thermal power generation from natural gas has increased globally due to its cleaner burning properties compared to other fossil fuels.
Cristian Alejandro Blanco-Martínez, Andrés Marino Álvarez-Meza, Germán Castellanos-Dominguez, David Augusto Cárdenas-Peña, Álvaro Angel Orozco-Gutiérrez   +4 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

CrowdAttention: An Attention Based Framework to Classify Crowdsourced Data in Medical Scenarios

Sensors
Supervised learning models in healthcare and other domains heavily depend on high-quality, labeled data. However, acquiring expert-verified labels (i.e., the gold standard) is often impractical due to cost, time, and subjectivity.
Julian Gil-Gonzalez, David Cárdenas-Peña, Álvaro A. Orozco, German Castellanos-Dominguez, Andrés Marino Álvarez-Meza   +4 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Electroencephalography-Based Pain Detection Using Kernel Spectral Connectivity Network with Preserved Spatio-Frequency Interpretability

Applied Sciences
Chronic pain leads to not only physical discomfort but also psychological challenges, such as depression and anxiety, which contribute to a substantial healthcare burden.
Santiago Buitrago-Osorio, Julian Gil-González, Andrés Marino Álvarez-Meza, David Cardenas-Peña, Alvaro Orozco-Gutierrez   +4 more
doaj   +1 more source

Fire alarm signal recognition

, 2001
The 1995 National Building Code of Canada requires that fire alarm signals sound the Temporal-Three (T-3) pattern, as defined by the ISO 8201 "Acoustics - Audible Emergency Evacuation Signal". This sound pattern has also been required by NFPA 72 since July 1996.
Proulx, G., Laroche, C., Jaspers-Fayer, F., Lavallée, R.   +3 more
openaire   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source