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Signal transducers and activators of transcription—from cytokine signalling to cancer biology

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2011
Signal transducers and activators of transcription (STATs) are, as the name indicates, both signal transducers and transcription factors. STATs are activated by cytokines and some growth factors and thus control important biological processes. These include cell growth, cell differentiation, apoptosis and immune responses.
Cristina Isabel, Santos   +1 more
openaire   +2 more sources

The role of signal transducers and activators of transcription in colon cancer

Frontiers in Bioscience, 2008
A family of latent cytoplasmic transcription factors, Signal Transducers and Activators of Transcription (STATs), convey signals from numerous cytokines and growth factors to the nucleus. Their expression and their activity have been shown to be perturbed in a variety of malignancies, including colorectal cancer.
openaire   +2 more sources

MicroRNAs and signal transducers and activators of transcription

Academic Journal of Second Military Medical University, 2013
Sha XU, Hou-qi LIU
openaire   +1 more source

Investigational therapies targeting signal transducer and activator of transcription 3 for the treatment of cancer

Expert Opinion on Investigational Drugs, 2015
Francesco Massari   +2 more
exaly  

A signal transducer and activator of transcription 6 haplotype influences the regulation of serum IgE levels

Journal of Allergy and Clinical Immunology, 2004
Michaela Schedel   +2 more
exaly  

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