Results 191 to 200 of about 26,543 (227)

Bending the boundaries: the many facets of endophilin-As from membrane dynamics to disease. [PDF]

Cell Mol Life Sci
Xu S, Rigaux E, Hène D, Renard HF, Thines L.   +4 more
europepmc   +1 more source

Clinical significance of YAP and androgen receptor expression in osteosarcoma: Evidence from a retrospective cohort study. [PDF]

Medicine (Baltimore)
Wang J, Xiang P, Zou C, Wang J.
europepmc   +1 more source

Unilateral isometric contraction induces REDD1 and suppresses insulin-stimulated mTORC1 and protein synthesis in non-contracted muscle of male mice. [PDF]

Physiol Rep
Amar MM, Murakami T.
europepmc   +1 more source

cGAMP Enhances Microglial/Macrophage Phagocytosis in Ischemic Stroke Via Activation of the TREM2-DAP10-PI3K Pathway. [PDF]

Inflammation
Li X, Ding H, Qian S, Hou Z, Yang G, Ma Y, Gao Y, Zhang Y, Li T.   +8 more
europepmc   +1 more source

Signal-transducing adaptor protein-2 regulates macrophage migration into inflammatory sites during dextran sodium sulfate induced colitis

Signal-transducing adaptor protein-2 regulates macrophage migration into inflammatory sites during dextran sodium sulfate induced colitis
openaire  

Graft-versus-host disease develops in mice transplanted with lymphocyte-depleted bone marrow cells from signal-transducing adaptor protein-2 transgenic mice

Graft-versus-host disease develops in mice transplanted with lymphocyte-depleted bone marrow cells from signal-transducing adaptor protein-2 transgenic mice
openaire  

Signal-transducing adaptor protein-1 and protein-2 in hematopoiesis and diseases

Experimental Hematology, 2021
Inflammatory and immune signals are involved in stressed hematopoiesis under myeloablation, infection, chronic inflammation, and aging. These signals also affect malignant pathogenesis, and the dysregulated immune environment which causes the resistance to treatment.
Michiko Ichii, Kenji Oritani, Jun Toda, Naoki Hosen, Tadashi Matsuda, Yuzuru Kanakura   +5 more
openalex   +3 more sources

Graft-versus-host disease develops in mice transplanted with lymphocyte-depleted bone marrow cells from signal-transducing adaptor protein-2 transgenic mice

Biochemical and Biophysical Research Communications, 2020
Graft-versus-host disease (GVHD) is the most frequent complication after allogeneic hematopoietic stem cell transplantation (HSCT), and is one of the major causes of non-relapse mortality. Transferred mature lymphocytes are thought to be responsible for GVHD based on the findings that mice transplanted with lymphocyte-depleted bone marrow (BM) cells ...
Hideaki Saito, Michiko Ichii, Jun Toda, Yuichi Kitai, Ryuta Muromoto, Jun‐ichi Kashiwakura, Kodai Saitoh, Akira Tanimura, Takafumi Yokota, Hirohiko Shibayama, Tadashi Matsuda, Kenji Oritani, Yuzuru Kanakura, Naoki Hosen   +13 more
openalex   +3 more sources

Abstract B34: Signal transducing adaptor protein 2 (STAP2) has the crucial role in maintaining the CTL function of memory T cells

Cancer Immunology Research, 2015
Abstract Purpose: Memory CD8+ T cells characterized the long survival after the strong activation followed by the appropriate antigenic stimulation have been believed to be an effective tumoricidal effectors in patients with cancer because they are possible to attack tumor cells repeatedly for a long time.
Daisuke Muraoka, Naohiro Seo, Tae Hayashi, Naozumi Harada, Hiroshi Shiku   +4 more
openalex   +2 more sources

Role of Signal-Transducing Adaptor Protein-1 for T Cell Activation and Pathogenesis of Autoimmune Demyelination and Airway Inflammation

The Journal of Immunology
Abstract Signal-transducing adaptor protein (STAP)-1 is an adaptor protein that is widely expressed in T cells. In this article, we show that STAP-1 upregulates TCR-mediated T cell activation and T cell–mediated airway inflammation. Using STAP-1 knockout mice and STAP-1–overexpressing Jurkat cells, we found that STAP-1 enhanced TCR ...
Kota Kagohashi, Yuto Sasaki, Kiyotaka Ozawa, Takuya Tsuchiya, Shoya Kawahara, Kodai Saitoh, Michiko Ichii, Jun Toda, Yasuyo Harada, Masato Kubo, Yuichi Kitai, Ryuta Muromoto, Kenji Oritani, Jun‐ichi Kashiwakura, Tadashi Matsuda   +14 more
openalex   +3 more sources