Results 1 to 10 of about 4,996,766 (248)
Mitochondrial signal transduction
Cell Metabolism, 2022 The analogy of mitochondria as powerhouses has expired. Mitochondria are living, dynamic, maternally inherited, energy-transforming, biosynthetic, and signaling organelles that actively transduce biological information. We argue that mitochondria are the processor of the cell, and together with the nucleus and other organelles they constitute the ...
M. Picard, O. Shirihai
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Signal transduction protocols [PDF]
European Journal of Histochemistry, 2012 Making Protein Immunoprecipitates Elaine A. Elion and Yunmei Wang Signal Transduction Inhibitors in Cellular Function Maofu Fu, Chenguang Wang, Xueping Zhang, and Richard G.
Michael D. Mendenhall, Robert C. Dickson
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Signal Transduction in Cancer [PDF]
Cold Spring Harbor Perspectives in Medicine, 2015 Cancer is driven by genetic and epigenetic alterations that allow cells to overproliferate and escape mechanisms that normally control their survival and migration. Many of these alterations map to signaling pathways that control cell growth and division, cell death, cell fate, and cell motility, and can be placed in the context of distortions of wider
Richard Sever, J. Brugge
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Signal transduction with a swing [PDF]
Nature Chemistry, 2021 The continuous monitoring of proteins is a current challenge in medical diagnostics. A new electrochemical approach aiming to address this has been described. The method uses antibodies as a recognition element to achieve the real-time measurement of proteins in saliva in the mouth.
Kevin J. Cash, Kevin W. Plaxco
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Artificial Signal Transduction [PDF]
ChemistryOpen, 2020 AbstractCommunication between and inside cells as well as their response to external stimuli relies on elaborated systems of signal transduction. They all require a directional transmission across membranes, often realized by primary messenger docking onto external receptor units and subsequent internalization of the signal in form of a released second
Robert Bekus, Thomas Schrader
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Targeting TGF-β signal transduction for fibrosis and cancer therapy
Molecular Cancer, 2022 Transforming growth factor β (TGF-β) has long been identified with its intensive involvement in early embryonic development and organogenesis, immune supervision, tissue repair, and adult homeostasis.
Dandan Peng +4 more
semanticscholar +1 more source
Role of relaxation time scale in noisy signal transduction [PDF]
, 2014 Intracellular fluctuations, mainly triggered by gene expression, are an inevitable phenomenon observed in living cells. It influences generation of phenotypic diversity in genetically identical cells.
Banik, Suman K. +2 more
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Epigenetics of cancer drug resistance
Academia Biology, 2023 One of the major causes due to cancer-related death is metastasis. The major factors contributing to metastasis of cancer cells are epithelial–mesenchymal transition and cancer stem cells.
Sayandeep Mukherjee +4 more
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Targeting PI3K/Akt signal transduction for cancer therapy
Signal Transduction and Targeted Therapy, 2021 The phosphatidylinositol 3-kinase (PI3K)/Akt pathway plays a crucial role in various cellular processes and is aberrantly activated in cancers, contributing to the occurrence and progression of tumors.
Yan He +6 more
semanticscholar +1 more source
AlphaPeptDeep: a modular deep learning framework to predict peptide properties for proteomics
Nature Communications, 2022 Deep learning (DL) has been frequently used in mass spectrometry-based proteomics but there is still a lot of potential. Here, the authors develop a framework that enables building DL models to predict arbitrary peptide properties with only a few lines ...
Wen-Feng Zeng +8 more
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