Results 1 to 10 of about 5,693,939 (420)
Mitochondrial signal transduction
Cell Metabolism, 2022 The analogy of mitochondria as powerhouses has expired. Mitochondria are living, dynamic, maternally inherited, energy-transforming, biosynthetic, and signaling organelles that actively transduce biological information. We argue that mitochondria are the processor of the cell, and together with the nucleus and other organelles they constitute the ...
M. Picard, O. Shirihai
semanticscholar +3 more sources
Finite-State Channel Models for Signal Transduction in Neural Systems [PDF]
, 2016 Information theory provides powerful tools for understanding communication systems. This analysis can be applied to intercellular signal transduction, which is a means of chemical communication among cells and microbes. We discuss how to apply information-theoretic analysis to ligand-receptor systems, which form the signal carrier and receiver in ...
Eckford, Andrew W. +2 more
arxiv +3 more sources
Signal transduction protocols [PDF]
European Journal of Histochemistry, 2012 The fascinating world of signal transduction is deeply, and clearly, investigated in this book edited by two leading scientists, Prof. Louis M. Luttrell (Dept. Medicine & Biochemistry & Molecular Biology, Medical University of South Carolina at Charleston) and Prof. Stephen S.G.
Robert C. Dickson, Michael D. Mendenhall
openaire +7 more sources
From data towards knowledge: Revealing the architecture of signaling systems by unifying knowledge mining and data mining of systematic perturbation data [PDF]
, 2013 Genetic and pharmacological perturbation experiments, such as deleting a gene and monitoring gene expression responses, are powerful tools for studying cellular signal transduction pathways. However, it remains a challenge to automatically derive knowledge of a cellular signaling system at a conceptual level from systematic perturbation-response data ...
Cowart, Ashley +3 more
arxiv +5 more sources
Dynamic receptor team formation can explain the high signal transduction gain in E. coli [PDF]
Biophysical Journal 86, 2650-2659 (2004), 2003 Evolution has provided many organisms with sophisticated sensory systems that enable them to respond to signals in their environment. The response frequently involves alteration in the pattern of movement, such as the chemokinesis of the bacterium Escherichia coli, which swims by rotating its flagella.
Ames +27 more
arxiv +5 more sources
Signal Transduction in Cancer [PDF]
Cold Spring Harbor Perspectives in Medicine, 2015 Cancer is driven by genetic and epigenetic alterations that allow cells to overproliferate and escape mechanisms that normally control their survival and migration. Many of these alterations map to signaling pathways that control cell growth and division, cell death, cell fate, and cell motility, and can be placed in the context of distortions of wider
Richard Sever, J. Brugge
semanticscholar +3 more sources
Artificial Signal Transduction [PDF]
ChemistryOpen, 2020 AbstractCommunication between and inside cells as well as their response to external stimuli relies on elaborated systems of signal transduction. They all require a directional transmission across membranes, often realized by primary messenger docking onto external receptor units and subsequent internalization of the signal in form of a released second
Robert Bekus, Thomas Schrader
openaire +5 more sources
Signal transduction with a swing [PDF]
Nature Chemistry, 2021 The continuous monitoring of proteins is a current challenge in medical diagnostics. A new electrochemical approach aiming to address this has been described. The method uses antibodies as a recognition element to achieve the real-time measurement of proteins in saliva in the mouth.
Kevin J. Cash, Kevin W. Plaxco
openaire +4 more sources
AlphaPeptDeep: a modular deep learning framework to predict peptide properties for proteomics
Nature Communications, 2022 Deep learning (DL) has been frequently used in mass spectrometry-based proteomics but there is still a lot of potential. Here, the authors develop a framework that enables building DL models to predict arbitrary peptide properties with only a few lines ...
Wen-Feng Zeng +8 more
doaj +1 more source
Piezo-optomechanical signal transduction using Lamb wave supermodes in a suspended Gallium Arsenide photonic integrated circuits platform [PDF]
Physical Review Applied 18, 054030, 2022, 2022 Piezoelectric optomechanical platforms present one of the most promising routes towards efficient transduction of signals from the microwave to the optical frequency domains. New device architectures need to be developed in order to achieve the stringent requirements for building efficient quantum transducers.
arxiv +1 more source