Results 1 to 10 of about 424,791 (85)

Role of relaxation time scale in noisy signal transduction [PDF]

open access: yes, 2014
Intracellular fluctuations, mainly triggered by gene expression, are an inevitable phenomenon observed in living cells. It influences generation of phenotypic diversity in genetically identical cells.
Banik, Suman K.   +2 more
core   +13 more sources

Ras p21 protein promotes survival and fiber outgrowth of cultured embryonic neurons [PDF]

open access: yes, 1989
Although evidence obtained with the PC12 cell line has suggested a role for the ras oncogene proteins in the signal transduction of nerve growth factor-mediated fiber outgrowth, little is known about the signal transduction mechanisms involved in the ...
Barde, Y. A.   +5 more
core   +2 more sources

Modeling Cell-to-Cell Communication Networks Using Response-Time Distributions. [PDF]

open access: yes, 2018
Cell-to-cell communication networks have critical roles in coordinating diverse organismal processes, such as tissue development or immune cell response. However, compared with intracellular signal transduction networks, the function and engineering
Altschuler, Steven J   +2 more
core   +2 more sources

Signal transduction gRABs attention [PDF]

open access: yes, 2006
Rab proteins are small GTPases involved in the regulation of vesicular membrane traffic. Research done in the past years has demonstrated that some of these proteins are under the control of signal transduction pathways.
Bucci, Cecilia, Chiariello, Mario
core   +1 more source

Self-organization of signal transduction

open access: yes, 2013
We propose a model of parameter learning for signal transduction, where the objective function is defined by signal transmission efficiency. We apply this to learn kinetic rates as a form of evolutionary learning, and look for parameters which satisfy ...
Scheler, Gabriele
core   +2 more sources

Finite-State Channel Models for Signal Transduction in Neural Systems

open access: yes, 2016
Information theory provides powerful tools for understanding communication systems. This analysis can be applied to intercellular signal transduction, which is a means of chemical communication among cells and microbes.
Eckford, Andrew W.   +2 more
core   +1 more source

Firing and signal transduction associated with an intrinsic oscillation in neuronal systems [PDF]

open access: yes, 1998
We study the nonlinear firing and signal transduction of a neuron subject to both a constant stimulus and a weak periodic signal, each of which is too small to, separately, fire spikes for the neuron.
Wang, W, Wang, Y, Wang, ZD
core   +1 more source

Fold-Hopf Bursting in a Model for Calcium Signal Transduction

open access: yes, 2002
We study a recent model for calcium signal transduction. This model displays spiking, bursting and chaotic oscillations in accordance with experimental results. We calculate bifurcation diagrams and study the bursting behaviour in detail.
Brusch, Lutz   +4 more
core   +1 more source

Optimal length and signal amplification in weakly activated signal transduction cascades

open access: yes, 2003
Weakly activated signaling cascades can be modeled as linear systems. The input-to-output transfer function and the internal gain of a linear system, provide natural measures for the propagation of the input signal down the cascade and for the ...
Chaves, Madalena   +2 more
core   +2 more sources

Approximations and their consequences for dynamic modelling of signal transduction pathways [PDF]

open access: yes, 2007
Signal transduction is the process by which the cell converts one kind of signal or stimulus into another. This involves a sequence of biochemical reactions, carried out by proteins.
Asthagiri   +49 more
core   +1 more source

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