Finite-State Channel Models for Signal Transduction in Neural Systems [PDF]
, 2016 Information theory provides powerful tools for understanding communication systems. This analysis can be applied to intercellular signal transduction, which is a means of chemical communication among cells and microbes.
Eckford, Andrew W. +2 more
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Dynamic receptor team formation can explain the high signal transduction gain in E. coli [PDF]
Biophysical Journal 86, 2650-2659 (2004), 2003 Evolution has provided many organisms with sophisticated sensory systems that enable them to respond to signals in their environment. The response frequently involves alteration in the pattern of movement, such as the chemokinesis of the bacterium ...
Ames +27 more
core +4 more sources
Role of functionality in two-component signal transduction: A stochastic study [PDF]
Phys Rev E 89 (2014) 032713, 2014 We present a stochastic formalism for signal transduction processes in bacterial two-component system. Using elementary mass action kinetics, the proposed model takes care of signal transduction in terms of phosphotransfer mechanism between the cognate ...
Bandyopadhyay, Arnab +3 more
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CD28 and T cell antigen receptor signal transduction coordinately regulate interleukin 2 gene expression in response to superantigen stimulation. [PDF]
, 1992 Activation of an immune response requires intercellular contact between T lymphocytes and antigen-presenting cells (APC). Interaction of the T cell antigen receptor (TCR) with antigen in the context of major histocompatibility molecules mediates signal ...
Fraser, JD, Newton, ME, Weiss, A
core +3 more sources
Piezo-optomechanical signal transduction using Lamb wave supermodes in a suspended Gallium Arsenide photonic integrated circuits platform [PDF]
Physical Review Applied 18, 054030, 2022, 2022 Piezoelectric optomechanical platforms present one of the most promising routes towards efficient transduction of signals from the microwave to the optical frequency domains. New device architectures need to be developed in order to achieve the stringent requirements for building efficient quantum transducers.
arxiv +1 more source
Epigenetics of cancer drug resistance
Academia Biology, 2023 One of the major causes due to cancer-related death is metastasis. The major factors contributing to metastasis of cancer cells are epithelial–mesenchymal transition and cancer stem cells.
Sayandeep Mukherjee +4 more
doaj +1 more source
AlphaPeptDeep: a modular deep learning framework to predict peptide properties for proteomics
Nature Communications, 2022 Deep learning (DL) has been frequently used in mass spectrometry-based proteomics but there is still a lot of potential. Here, the authors develop a framework that enables building DL models to predict arbitrary peptide properties with only a few lines ...
Wen-Feng Zeng +8 more
doaj +1 more source
Optimized protocols for duplex quantum transduction [PDF]
Phys. Rev. Lett. 131, 220802 (2023), 2023 Quantum transducers convert quantum signals through hybrid interfaces of physical platforms in quantum networks. Modeled as quantum communication channels, performance of unidirectional quantum transduction can be measured by the quantum channel capacity.
arxiv +1 more source
Scientific Reports, 2021 Angiogenesis contributes to numerous pathological conditions. Understanding the molecular mechanisms of angiogenesis will offer new therapeutic opportunities. Several experimental in vivo models that better represent the pathological conditions have been
Yohei Tsukada +7 more
doaj +1 more source
Endothelial cell-derived Apelin inhibits tumor growth by altering immune cell localization
Scientific Reports, 2021 The Apelin/APJ signalling pathway, involved in multiple physiological and pathological processes, has been attracting increasing interest recently. In our previous study, Apelin overexpression in colon26 tumor cells suppressed tumor growth by inducing ...
Liuying Hu +3 more
doaj +1 more source