Results 261 to 270 of about 9,547,943 (379)
An Energy Budget for Signaling in the Grey Matter of the Brain
Journal of Cerebral Blood Flow and Metabolism, 2001 D. Attwell, S. Laughlin
semanticscholar +1 more source
Molecular Oncology, EarlyView.Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
wiley +1 more source
HA14-1, but not the BH3 mimetic ABT-737, causes Ca2+ dysregulation in platelets and human cell lines
Haematologica, 2013 Haidar Akl +9 more
doaj +1 more source
Decoding Sepsis: Unraveling Key Signaling Pathways for Targeted Therapies. [PDF]
Research (Wash D C)Tang L +6 more
europepmc +1 more source
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
Cell, 2009 Raphael Kopan, M. Ilagan
semanticscholar +1 more source
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
Molecular Oncology, EarlyView.In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza +3 more
wiley +1 more source
Discovering anticancer drug target combinations via network-informed signaling-based approach. [PDF]
Commun Med (Lond)Yavuz BR, Jang H, Nussinov R.
europepmc +1 more source
Regulation mechanisms and signaling pathways of autophagy.
Annual Review of Genetics, 2009 Congcong He, D. Klionsky
semanticscholar +1 more source