Results 31 to 40 of about 5,041,480 (330)
Information-theoretic analysis of multivariate single - cell signaling responses using SLEMI
, 2018 Mathematical methods of information theory constitute essential tools to describe how stimuli are encoded in activities of signaling effectors.
Blonski, Slawomir +4 more
core +1 more source
Redox signaling, Nox5 and vascular remodeling in hypertension [PDF]
, 2015 Purpose of review: Extensive data indicate a role for reactive oxygen species (ROS) and redox signaling in vascular damage in hypertension. However, molecular mechanisms underlying these processes remain unclear, but oxidative post-translational ...
De Lucca Camargo, Livia +5 more
core +1 more source
Trends in Biotechnology, 2014 Signaling pathways function as the information-passing mechanisms of cells. A number of databases with extensive manual curation represent the current knowledge base for signaling pathways. These databases motivate the development of computational approaches for prediction and analysis.
Anna, Ritz +4 more
openaire +2 more sources
A multi‐scale approach reveals that NF‐κB cRel enforces a B‐cell decision to divide
Molecular Systems Biology, 2015 Understanding the functions of multi‐cellular organs in terms of the molecular networks within each cell is an important step in the quest to predict phenotype from genotype.
Maxim N Shokhirev +6 more
doaj +1 more source
Automated single-molecule imaging in living cells
Nature Communications, 2018 Large scale live cell screens often lack single-molecule resolution. Here the authors present an artificial intelligence-assisted TIRF microscope with automated cell searching and focusing, and use it for high-throughput single-molecule imaging of EGFR ...
Masato Yasui +4 more
doaj +1 more source
Cell Death Discovery, 2022 Ferroptosis is a caspase-independent form of regulated cell death strongly linked to the accumulation of reactive lipid hydroperoxides. Lipid hydroperoxides are neutralized in cells by glutathione peroxidase 4 (GPX4) and inhibitors of GPX4 are potent ...
Tanu Singh +2 more
doaj +1 more source
Front-propagation in bacterial inter-colony communication
, 2018 Many bacterial species exchange signaling molecules to coordinate population-wide responses. For this process known as quorum sensing the concentration of the respective molecules is crucial. Here we consider the interaction between spatially distributed
Becker, Anke +3 more
core +1 more source
Rapamycin induces transactivation of the EGFR and increases cell survival. [PDF]
, 2009 The mammalian target of rapamycin (mTOR) signaling network regulates cell growth, proliferation and cell survival. Deregulated activation of this pathway is a common event in diverse human diseases such as cancers, cardiac hypertrophy, vascular ...
Chaturvedi, D +4 more
core +2 more sources
Cellular MicrobiologyTrial Registration: ClinicalTrials.gov identifier: NCT01473524 ...
Gayatri Reghu +3 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li +9 more
wiley +1 more source