Results 121 to 130 of about 403,629 (240)

Interoceptive Signals Bias Decision Making in Rhesus Macaques

AbstractSeveral influential theories have proposed that interoceptive signals, sent from the body to the brain, contribute to neural processes that coordinate complex behaviors. We altered the physiological state of the body using compounds that have minimal effect on the brain and evaluated their effect on decision-making in rhesus monkeys.
Michael A. Cardenas, Ryan P. Le, Tess M. Champ, Derek O’Neill, Andrew J. Fuglevand, Katalin M. Gothard   +5 more
openaire   +2 more sources

Structural visualization of small molecule recognition by CXCR3 uncovers dual-agonism in the CXCR3-CXCR7 system

Nature Communications
Chemokine receptors are critically involved in multiple physiological and pathophysiological processes related to immune response mechanisms. Most chemokine receptors are prototypical GPCRs although some also exhibit naturally-encoded signaling-bias ...
Shirsha Saha, Fumiya K. Sano, Saloni Sharma, Manisankar Ganguly, Annu Dalal, Sudha Mishra, Divyanshu Tiwari, Hiroaki Akasaka, Takaaki A. Kobayashi, Nabarun Roy, Nashrah Zaidi, Yuzuru Itoh, Rob Leurs, Ramanuj Banerjee, Wataru Shihoya, Osamu Nureki, Arun K. Shukla   +16 more
doaj   +1 more source

Modeling branching and chiral colonial patterning of lubricating bacteria

, 1998
In nature, microorganisms must often cope with hostile environmental conditions. To do so they have developed sophisticated cooperative behavior and intricate communication capabilities, such as: direct cell-cell physical interactions via extra-membrane ...
Ben-Jacob, Eshel, Cohen, Inon, Golding, Ido, Kozlovsky, Yonathan   +3 more
core   +1 more source

Inhibition of Notch signaling biases rat thymocyte development towards the NK cell lineage [PDF]

, 2004
Jens van den Brandt, Katrin Voß, Melanie Schott, Thomas Hünig, Michael S. Wolfe, Holger M. Reichardt   +5 more
openalex   +1 more source

How visual confidence on global motion is affected by local motion ambiguity and type of motion noise, and its correlation with autistic trait tendency?

, 2019
Perceptual confidence has been found to correlate with task performance in general, and is believed to be independent of stimulus features. However, certain stimulus feature could induce a subjective sense of uncertainty, which could potentially ...
LAM, Man Wai, Angela
core  

Signaling bias of the protease-activated receptor-1 is dictated by distinct GRK5 and β-arrestin-2 determinants

Cell Reports
Summary: G protein-coupled receptors (GPCRs) exhibit signaling bias or preferential activation of heterotrimeric G proteins versus GPCR kinase (GRK)-mediated β-arrestin signaling.
Monica L. Gonzalez Ramirez, Lennis B. Orduña-Castillo, Carolyne Bardeleben, Huaping Qin, Ying Lin, Cierra A. Birch, Irina Kufareva, JoAnn Trejo   +7 more
doaj   +1 more source

APPLYING SIGNAL‐DETECTION THEORY TO THE STUDY OF OBSERVER ACCURACY AND BIAS IN BEHAVIORAL ASSESSMENT [PDF]

, 2010
Dorothea C. Lerman, Allison Tetreault, Alyson Hovanetz, Emily Bellaci, Jonathan R. Miller, Hilary Jo Karp, Angela Mahmood, Maggie Strobel, Shelley Mullen, Alice Keyl, Alexis Toupard   +10 more
openalex   +1 more source

Inside the Black Box: Detecting and Mitigating Algorithmic Bias Across Racialized Groups in College Student-Success Prediction

AERA Open
Colleges and universities are increasingly turning to algorithms that predict college-student success to inform various decisions, including those related to admissions, budgeting, and student-success interventions.
Denisa Gándara, Hadis Anahideh, Matthew P. Ison, Lorenzo Picchiarini   +3 more
doaj   +1 more source

Mechanism of activation and biased signaling in complement receptor C5aR1 [PDF]

, 2023
Yuying Feng, Chang Zhao, Yue Deng, Heli Wang, Liang Ma, Sicen Liu, Xiaowen Tian, Bo Wang, Bin Yan, Peipei Chen, Wei Yan, Ping Fu, Zhenhua Shao   +12 more
openalex   +1 more source

Mechanoactivation of the angiotensin II type 1 receptor induces β‐arrestin‐biased signaling through Gα_icoupling

, 2017
Jialu Wang, Kenji Hanada, Clarice Gareri, Howard A. Rockman   +3 more
openalex   +2 more sources