Results 271 to 273 of about 6,937,440 (273)

Methods to Quantify Cell Signaling and GPCR Receptor Ligand Bias: Characterization of Drugs that Target the Endocannabinoid Receptors in Huntington's Disease.

Methods in molecular biology, 2018
A. Bagher, R. Laprairie, M. Kelly, E. Denovan‐Wright   +3 more
semanticscholar   +1 more source

GPCR signaling: bias, kinetics and compartmentalization

G-protein coupled receptors (GPCRs) constitute a family of cell membrane receptors crucial for intercellular communication. In mammals,they play a pivotal role in regulating fundamental processes, including reproduction and social interactions. Upon activation by hormones atthe cell membrane, GPCRs initiate a cascade of intracellular reactions ...
openaire   +1 more source

S-Nitrosylation of GPCR Regulatory Machinery as a Mechanism to Bias Signaling

Handbook of Experimental Pharmacology
Richard T Premont, Zachary Grimmett, Jonathan S Stamler   +2 more
exaly