Results 271 to 280 of about 442,339 (288)
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The Measurement of Receptor Signaling Bias

2015
This chapter describes a method to quantify biased signaling effects of agonists; this approach can furnish a scale for medicinal chemists to optimize biased profiles. Biased ligands have different pharmacological properties on a molecular level (stabilization of different receptor active states) and thus can have different pharmacological profiles ...
openaire   +2 more sources

Bounds on the Bias of Signal Parameter Estimators

Bell System Technical Journal, 1969
Any estimator which is constrained to take values in a finite range is, in general, biased. Many times the bias is unknown; furthermore, in some cases the bias may become the main contributor to the mean square error of an estimator. This paper derives upper and lower bounds on the bias of a finite-range, signal parameter estimator.
openaire   +2 more sources

The effect of nonlinear signal transformations on bias errors in elastography

IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, 2000
We have reported several artifacts in elastography (1991). These include mechanical artifacts, such as stress concentration, and signal processing artifacts, such as zebras, which are caused by bias errors incurred during the estimation of the peak of correlation functions using a curve-fitting method.
S K, Alam, J, Ophir
openaire   +2 more sources

Bias analysis on return signal simulator of radar altimeter

Proceedings of 2011 International Conference on Electronic & Mechanical Engineering and Information Technology, 2011
The radar altimeter prelaunch calibration was commonly carried our by return signal simulator. The principles of return signal simulator, biases such as quadratic phase bias, amplitude and phase biases, delay bias were described in detail in this paper. In the last section the overall system bias on return signal simulator was calculated.
Chuan-dong Xu, Xi-Yu Xu, Shuangbao Yang
openaire   +1 more source

Signal Analysis in Back Bias Speed Sensor Systems

2013 European Modelling Symposium, 2013
Wheel speed sensors determine the angular velocity of rotating axes and are widely used in modern industry with a variety of applications. This paper provides a general introduction to back bias speed sensor systems, presenting and discussing the numerous parameters of a general 3D model.
Michael Ortner   +3 more
openaire   +1 more source

Ranging Bias of COMPASS Satellite Signals

2015
Quantitative evaluation of signal quality of navigation satellites in orbit is one of the difficulties in satellite navigation signal quality monitoring research, so a quantitative evaluation method based on theoretic ranging bias is proposed. Based on Vernier sampling principle and a large diameter parabolic antenna is used for in-orbit satellite ...
Jiancheng Liu   +3 more
openaire   +1 more source

Invisible overtures: Fears of rejection and the signal amplification bias.

Journal of Personality and Social Psychology, 2003
Four studies demonstrated that fears of rejection prompt individuals to exhibit a signal amplification bias, whereby they perceive that their overtures communicate more romantic interest to potential partners than is actually the case. The link between rejection anxieties and the bias was evident regardless of whether fears of rejection were assessed ...
Jacquie D, Vorauer   +3 more
openaire   +2 more sources

Fusion with Promiscuous Gα16 Subunit Reveals Signaling Bias at Muscarinic Receptors

International Journal of Molecular Sciences, 2021
Alena Randáková   +2 more
exaly  

How can we improve the measurement of receptor signaling bias?

Expert Opinion on Drug Discovery, 2023
Karim Nagi
exaly  

Ligand-directed bias of G protein signaling at the dopamine D2 receptor

Cell Chemical Biology, 2022
Ee Von Moo   +2 more
exaly  

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