Results 281 to 288 of about 442,339 (288)

Signaling diversity of mu- and delta- opioid receptor ligands: Re-evaluating the benefits of β-arrestin/G protein signaling bias

Cellular Signalling, 2021
Graciela Piñeyro, Karim Nagi
exaly  

Diversity of the Gβγ complexes defines spatial and temporal bias of GPCR signaling

Cell Systems, 2021
Ikuo Masuho, Brian S Muntean, Kirill A Martemyanov   +2 more
exaly  

Luciferase Complementation Approaches to Measure GPCR Signaling Kinetics and Bias

Methods in Molecular Biology, 2021
Nicholas D Holliday
exaly  

"Signaling, Prior-bias and Welfare Implications"

The Korean Journal of Economics, 2020
Eunjee Joo, Yong-Ju Lee
openaire   +1 more source

Cannabinoid CB 1 and CB 2 Receptor Signaling and Bias

Cannabis and Cannabinoid Research, 2017
Mark Connor, Michelle Glass
exaly  

GPCR signaling: bias, kinetics and compartmentalization

G-protein coupled receptors (GPCRs) constitute a family of cell membrane receptors crucial for intercellular communication. In mammals,they play a pivotal role in regulating fundamental processes, including reproduction and social interactions. Upon activation by hormones atthe cell membrane, GPCRs initiate a cascade of intracellular reactions ...
openaire   +1 more source

Structure–Activity Relationship Studies of Functionally Selective Kappa Opioid Receptor Agonists that Modulate ERK 1/2 Phosphorylation While Preserving G Protein Over βArrestin2 Signaling Bias

ACS Chemical Neuroscience, 2015
Kimberly M Lovell, Kevin J Frankowski, Edward L Stahl   +2 more
exaly  

S-Nitrosylation of GPCR Regulatory Machinery as a Mechanism to Bias Signaling

Handbook of Experimental Pharmacology
Mingda Chen, Zachary W Grimmett, Richard T Premont   +2 more
exaly