Results 81 to 90 of about 403,629 (240)
Health Equity, 2023 Introduction: Despite mounting evidence that the inclusion of race and ethnicity in clinical prediction models may contribute to health disparities, existing critical appraisal tools do not directly address such equity considerations.
doaj +1 more source
A 6.0-mW 10.0-Gb/s Receiver With Switched-Capacitor Summation DFE [PDF]
, 2007 A low-power receiver with a one-tap decision feedback equalization (DFE) was fabricated in 90-nm CMOS technology. The speculative equalization is performed using switched-capacitor-based addition at the front-end sample-hold circuit.
Bulchacchelli, John F. +5 more
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G Protein‐Coupled Receptor Signaling: Implications and Therapeutic Development Advances in Cancers
MedCommG protein‐coupled receptors (GPCRs) are the largest and most diverse class of membrane proteins, mediating cellular responses to a wide range of extracellular stimuli.
Inamu Rashid Khan +6 more
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Biased agonism: the quest for the analgesic holy grail
PAIN Reports, 2018 . Opioids alleviate pain, but adverse effects severely limit their usefulness. To solve this problem, biased ligands favoring 1 signaling pathway downstream of the μ-opioid receptor over another are being developed.
M. Alexander Stanczyk, Ram Kandasamy
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Prolonged calcitonin receptor signaling by salmon, but not human calcitonin, reveals ligand bias. [PDF]
PLoS ONE, 2014 Salmon calcitonin (sCT) and human calcitonin (hCT) are pharmacologically distinct. However, the reason for the differences is unclear. Here we analyze the differences between sCT and hCT on the human calcitonin receptor (CT(a)R) with respect to ...
Kim Vietz Andreassen +7 more
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On the Number of Bins in Equilibria for Signaling Games
, 2019 We investigate the equilibrium behavior for the decentralized quadratic cheap talk problem in which an encoder and a decoder, viewed as two decision makers, have misaligned objective functions.
Furrer, Philippe +4 more
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Beyond product markets: new insight on liability of foreignness from capital markets [PDF]
, 2011 We expand the Liability of Foreignness (LOF) construct beyond the product market domain to include liabilities faced by firms attempting to secure resources in host capital markets. Drawing from institutional theory and research in finance, we identify
Bell, R. Greg +2 more
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Scaffold Analysis of Ligands Exhibiting GPCR Signaling Bias [PDF]
, 2020 Signaling bias is a feature of many G–protein coupled receptor (GPCR) modulating drugs with clinical implications. Whether it is therapeutically advantageous for a drug to be G Protein biased or β -Arrestin ( β -Arr) biased, depends on the context of the ...
Jason Sanchez +3 more
openaire +1 more source
The impossibility of non-signaling privacy amplification
, 2009 Barrett, Hardy, and Kent have shown in 2005 that protocols for quantum key agreement exist the security of which can be proven under the assumption that quantum or relativity theory is correct.
Hänggi, Esther +2 more
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Ligand bias underlies differential signaling of multiple FGFs via FGFR1
eLifeThe differential signaling of multiple FGF ligands through a single fibroblast growth factor (FGF) receptor (FGFR) plays an important role in embryonic development.
Kelly Karl +8 more
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