Results 291 to 300 of about 8,752,965 (357)

Wnt signaling pathway: A comprehensive review

Cell Biology International, 2022
Wnt signaling is an evolutionary cell‐to‐cell coordination mechanism and it is highly critical for a variety of physiological processes of an organism's body, including stem cell regeneration, proliferation, division, migration, polarity of a cell ...
Rabia Hayat, M. Manzoor, A. Hussain
semanticscholar   +1 more source

Attacking the PI3K/Akt/mTOR signaling pathway for targeted therapeutic treatment in human cancer.

Seminars in Cancer Biology, 2021
Cancer is the second leading cause of human death globally. PI3K/Akt/mTOR signaling is one of the most frequently dysregulated signaling pathways observed in cancer patients that plays crucial roles in promoting tumor initiation, progression and therapy ...
Le Yu, Jessica Wei, Pengda Liu
semanticscholar   +1 more source

Targeting the PDGF/PDGFR signaling pathway for cancer therapy: A review.

International Journal of Biological Macromolecules, 2022
Platelet-derived growth factors (PDGFs) and PDGF receptors (PDGFRs) are expressed in a variety of tumors. Activation of the PDGF/PDGFR signaling pathway is associated with cancer proliferation, metastasis, invasion, and angiogenesis through modulating ...
X. Zou   +6 more
semanticscholar   +1 more source

Apoptosis Signaling Pathways

Current Protocols in Cytometry, 2001
AbstractCell death is often an active and highly choreographed process of cell suicide known as apoptosis. The molecular signals governing this process have been the subject of intense research in recent years. During apoptosis a profusion of pathways either promote cellular survival or lead to certain death. These pathways engage in constant crosstalk
Richard M, Siegel, Michael J, Lenardo
openaire   +3 more sources

Prokineticin-signaling pathway

The International Journal of Biochemistry & Cell Biology, 2008
Prokineticin signaling comprises two secreted proteins (Prok-1 and Prok-2) and two cognate G-protein coupled receptors (PK-R1 and PK-R2) that are widely expressed in different tissues and of great versatility. Prokineticins were originally identified as the potent agents mediating gut motility in the digestive system, but were later shown to promote ...
Tam, PKH, Ngan, ESW
openaire   +4 more sources

Brassinosteroid Signaling Pathway

Science's STKE, 2006
Plant growth is regulated by an intricate network of hormonal signaling pathways. These small-molecule hormones cause changes in gene expression that are associated with cell expansion and division and changes in development. Paradoxically, six of these hormones appear to have largely overlapping functions, yet the loss of response to any ...
Youssef, Belkhadir   +2 more
openaire   +2 more sources

Ethylene Signaling Pathway

Science's STKE, 2005
The structural simplicity of the plant hormone ethylene contrasts with its dramatic effects in various developmental processes, as well as in the cellular processes that ethylene initiates in response to a diversity of environmental signals. A single well-conserved signaling cascade mediates this broad spectrum of responses.
Anna N, Stepanova, Jose M, Alonso
openaire   +2 more sources

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