Results 1 to 10 of about 258,608 (128)

LPAR1 Promotes Activation of Pathways Alveolar Hypercoagulation and Fibrinolytic Inhibition in ARDS via NF‐κB Signaling Pathway [PDF]

FASEB BioAdvances
Alveolar hypercoagulation and fibrinolytic inhibition are critical mechanisms contributing to refractory hypoxemia in acute respiratory distress syndrome (ARDS).
Ying Liu, Xianjun Chen, Meng Liu, Jia Yuan, Qing Li, Lu Li, Qi Dong, Junling Tao, Feng Shen, Chuan Xiao   +9 more
doaj   +2 more sources

Effects of the NF-κB Signaling Pathway Inhibitor BAY11-7082 in the Replication of ASFV

Viruses, 2022
African swine fever virus (ASFV) mainly infects the monocyte/macrophage lineage of pigs and regulates the production of cytokines that influence host immune responses. Several studies have reported changes in cytokine production after infection with ASFV,
Qi Gao, Yunlong Yang, Yongzhi Feng, Weipeng Quan, Yizhuo Luo, Heng Wang, Jiachen Zheng, Xiongnan Chen, Zhao Huang, Xiaojun Chen, Runda Xu, Guihong Zhang, Lang Gong   +12 more
doaj   +1 more source

cGMP signaling pathway that modulates NF-κB activation in innate immune responses

iScience, 2021
Summary: The nuclear factor-kappa B (NF-κB) pathway is an evolutionarily conserved signaling pathway that plays a central role in immune responses and inflammation. Here, we show that Drosophila NF-κB signaling is activated via a pathway in parallel with
Hirotaka Kanoh, Shinzo Iwashita, Takayuki Kuraishi, Akira Goto, Naoyuki Fuse, Haruna Ueno, Mariko Nimura, Tomohito Oyama, Chang Tang, Ryo Watanabe, Aki Hori, Yoshiki Momiuchi, Hiroki Ishikawa, Hiroaki Suzuki, Kumiko Nabe, Takeshi Takagaki, Masataka Fukuzaki, Li-Li Tong, Sinya Yamada, Yoshiteru Oshima, Toshiro Aigaki, Julian A.T. Dow, Shireen-Anne Davies, Shoichiro Kurata   +23 more
doaj   +1 more source

The protective activity of natural flavonoids against osteoarthritis by targeting NF-κB signaling pathway

Frontiers in Endocrinology, 2023
Osteoarthritis (OA) is a typical joint disease associated with chronic inflammation. The nuclear factor-kappaB (NF-κB) pathway plays an important role in inflammatory activity and inhibiting NF-κB-mediated inflammation can be a potential strategy for ...
Yongjun Ye, Jianguo Zhou
doaj   +1 more source

Progress and Prospects of Non-Canonical NF-κB Signaling Pathway in the Regulation of Liver Diseases

Molecules, 2022
Non-canonical nuclear factor kappa B (NF-κB) signaling pathway regulates many physiological and pathological processes, including liver homeostasis and diseases.
Li Tao, Xiaomeng Ren, Wenhui Zhai, Zheng Chen   +3 more
doaj   +1 more source

BYHWD Alleviates Inflammatory Response by NIK-Mediated Repression of the Noncanonical NF-κB Pathway During ICH Recovery

Frontiers in Pharmacology, 2021
Intracerebral hemorrhage (ICH) is a life-threatening type of stroke that lacks effective treatments. The inflammatory response following ICH is a vital response that affects brain repair and organism recovery.
Wei Xiao, Zehui He, Weikang Luo, Dandan Feng, Yang Wang, Tao Tang, Ali Yang, Jiekun Luo   +7 more
doaj   +1 more source

TLR4-MyD88-NF-κB signaling pathway contributes to the progression of secondary hepatic injury and fibrosis in hepatolithiasis

European Journal of Inflammation, 2021
This paper focused on evaluating the effect of TLR4-MyD88-NF-κB signaling pathway in the progression of secondary hepatic injury and fibrosis in hepatolithiasis.
Yuan Fang, Lulu Zhou, Xiaoxuan Hu, Jingyun Guo, Jinmao Liao, Zheng Zhang   +5 more
doaj   +1 more source

The Expression of NF-kB Signaling Pathway Was Inhibited by Silencing TGF-b4 in Chicken IECs Infected with E. tenella [PDF]

Brazilian Journal of Poultry Science, 2020
Chicken coccidiosis is a parasitic disease caused by one or more species of Eimeria infection with severe consequences. The NF-κB signaling pathway and TGF-β4 play an important role in the inflammation and immune response caused by coccidiosis infection.
H Jin, Y Haicheng, Z Caiyun, Z Yong, W Jinrong   +4 more
doaj   +1 more source

Chicken telomerase reverse transcriptase mediates LMH cell pyroptosis by regulating the nuclear factor-kappa B signaling pathway

Poultry Science, 2022
: The activation of human telomerase reverse transcriptase is regulated by the nuclear factor kappa B (NF-κB) signaling pathway to various degrees to promote the occurrence and development of tumors.
Yong Xiang, Yun Yu, Qingbo Li, Jian Chen, Yu Li, Weisheng Cao   +5 more
doaj   +1 more source

Research progress on the effect of traditional Chinese medicine on the activation of PRRs-mediated NF-κB signaling pathway to inhibit influenza pneumonia

Frontiers in Pharmacology, 2023
Influenza pneumonia has challenged public health and social development. One of the hallmarks of severe influenza pneumonia is overproduction of pro-inflammatory cytokines and chemokines, which result from the continuous activation of intracellular ...
Ling Zhang, Xiong Ye, Yuntao Liu, Zhongde Zhang, Xueshan Xia, Shuwei Dong   +5 more
doaj   +1 more source