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Signaling pathways in phagocytosis
BioEssays, 1999Phagocytosis is an uptake of large particles governed by the actin-based cytoskeleton. Binding of particles to specific cell surface receptors is the first step of phagocytosis. In higher Eucaryota, the receptors able to mediate phagocytosis are expressed almost exclusively in macrophages, neutrophils, and monocytes, conferring immunodefence properties
K, Kwiatkowska, A, Sobota
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Current Opinion in Biotechnology, 2019
The last decade has seen a rise in the development of methods and models to analyze cellular networks on all levels. The applications of this knowledge are, however, often confined to specifics of the network in concrete conditions and leveraging it is hampered by the lack of information about this context and its implications on the system.
Friedemann, Uschner, Edda, Klipp
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The last decade has seen a rise in the development of methods and models to analyze cellular networks on all levels. The applications of this knowledge are, however, often confined to specifics of the network in concrete conditions and leveraging it is hampered by the lack of information about this context and its implications on the system.
Friedemann, Uschner, Edda, Klipp
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Signaling pathways in glioblastoma
Critical Reviews in Oncology/HematologyCancer is one of the main public health problems worldwide. Among tumors of the Central Nervous System (CNS), glioblastoma (GBM) affects 49.1 % of malignant brain tumors, and despite standard treatment, patients diagnosed with GBM have a dismal prognosis, a high rate of recurrence after tumor resection and poor survival.
Isabella Gomes +2 more
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Angiogenic Signalling Pathways
2008Hypoxia is widely recognised as a key driving force for tumor angiogenesis by its induction of vascular endothelial growth factor (VEGF) and other direct-acting angiogenic factors. We describe the effect of hypoxia on gene expression and downstream angiogenic signalling; however, the angiogenic process is complex, and many other signalling pathways ...
Zubair, Ahmed, Roy, Bicknell
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Crossroads of Signaling Pathways
2013As studies on PC progression continue to uncover a growing number of crosstalks and co-occurrences of mutations and epigenetic alterations, new drugs are getting approved bringing significant changes in the treatment paradigm of these tumors.
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Basophil Stimulation and Signaling Pathways
2014Despite the growing use of flow cytometry to analyze the functional characteristics of basophils, the intracellular signaling cascades that control their ability to elaborate various pro-allergic and inflammatory mediators and cytokines remain comparatively obscure.
Edward F, Knol, Bernhard F, Gibbs
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p38MAPK Signaling Pathway in Osteoarthritis: Pathological and Therapeutic Aspects
Journal of Inflammation Research, 2022Zhenhan Deng
exaly