Results 81 to 90 of about 2,211,530 (330)

Gene expression patterns following unilateral traumatic brain injury reveals a local pro-inflammatory and remote anti-inflammatory response. [PDF]

open access: yes, 2013
BackgroundTraumatic brain injury (TBI) results in irreversible damage at the site of impact and initiates cellular and molecular processes that lead to secondary neural injury in the surrounding tissue.
Ford, Byron D   +5 more
core   +2 more sources

Neurophysiology and signaling pathways [PDF]

open access: yesMedicinski casopis, 2017
© 2017, Serbian Medical Society. All rights reserved. An important starting step in understanding the neurobiology of memory lies in identifying locations of physical and chemical changes that follow cognition. As Hebb indicated, and as shown on computer models, memory is a consequence of subtle alterations in synapses.
Matic, Ivana, Zivkovic, Vladimir
openaire   +3 more sources

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Extracellular vesicles (EVs) mediate intercellular communication in tumor immune microenvironments. However, their role in B‐cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

Signaling pathways in hair aging

open access: yesFrontiers in Cell and Developmental Biology, 2023
Hair follicle (HF) homeostasis is regulated by various signaling pathways. Disruption of such homeostasis leads to HF disorders, such as alopecia, pigment loss, and hair aging, which is causing severe health problems and aesthetic concerns.
Aishi Liang   +6 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Towards an enhanced understanding of osteoanabolic effects of PTH-induced microRNAs on osteoblasts using a bioinformatic approach

open access: yesFrontiers in Endocrinology
In this study, we used a bioinformatic approach to construct a miRNA-target gene interaction network potentially involved in the anabolic effect of parathyroid hormone analogue teriparatide [PTH (1–34)] on osteoblasts.
Lucija Ana Vrščaj   +3 more
doaj   +1 more source

Information transfer in signaling pathways : a study using coupled simulated and experimental data [PDF]

open access: yes, 2008
Background: The topology of signaling cascades has been studied in quite some detail. However, how information is processed exactly is still relatively unknown.
Pahle, Jürgen   +3 more
core   +5 more sources

Signaling pathways linking behavior to neurogenesis in healthy brain and disease [PDF]

open access: yes, 2020
Self-repair of the adult brain is limited – most diseases lack effective therapy. In order to better understand how a regenerative response can be achieved, studying mechanisms shaping the neurogenic niche, from environmental factors to intrinsic ...
Klempin, Friederike
core   +1 more source

Keap1/Nrf2 Signaling Pathway [PDF]

open access: yesAntioxidants, 2021
Nuclear factor, erythroid 2-like transcription factor 2 (Nrf2) and its cytoplasmic inhibitor, kelch-like ECH-associated protein 1 (Keap1), comprise a redox-responsive endogenous antioxidant defense module that orchestrates the expression of cytoprotective genes to maintain homeostasis [...]
openaire   +4 more sources

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

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